Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Proglumetacin"'
Autor:
Francis Ginsberg, Daniel Lefebvre
Publikováno v:
Current Therapeutic Research. 56:1237-1246
In an uncontrolled, open-label, multicenter study, 711 outpatients with either cervical pain (n = 200) or low-back pain (n = 511) received 450 mg/d of proglumetacin, a pro-drug of indomethacin. After 7 days of treatment, a highly significant reductio
Autor:
Marc Martens
Publikováno v:
Current Therapeutic Research. 56:639-648
The efficacy and safety of oral proglumetacin versus naproxen sodium were assessed in a double-blind, randomized, parallel-group prospective study of 41 patients with ankle sprains. The treatment lasted 2 weeks (with an additional week of treatment i
Publikováno v:
Current Therapeutic Research. 55:1372-1381
In an uncontrolled, open trial, 182 outpatients suffering from either overuse syndromes (n = 68) or minor traumas (n = 114) resulting from soccer practice received proglumetacin, a prodrug of indomethacin, for 10 days, at a dose of 600 mg/d from day
Publikováno v:
Current Therapeutic Research. 55:309-318
In an uncontrolled open trial, 317 outpatients suffering from soft-tissue rheumatisms (ie, 148 patients with painful shoulder, 92 with tendinitis, 42 with epicondylitis, and 35 with minor traumas) received 450 mg/day of proglumetacin, a prodrug of in
Publikováno v:
Current Therapeutic Research. 53:630-634
In a randomized, parallel-group study, 44 young adults with acute ankle sprains were treated with proglumetacin or diclofenac. The patients were examined daily for pain, swelling, and impaired mobility during the 7-day treatment period. The needed du
Publikováno v:
Ensho. 13:477-482
As it has been known that non-steroidal anti-inflammatory drugs have damaging effect on gastric mucosa which may be related to superoxide production by neutrophils as indicated in recent reports, we evaluated the effect of indomethacin prodrugs (acem
Autor:
Toru Endo, Hiroyuki Uemura, Koji Kusakari, Hideki Matsui, Yutaka Mizushima, Akira Yanagawa, Takemasa Nakagawa, Tadashi Fukumura
Publikováno v:
Ensho. 11:479-487
A controlled double blind study was performed for 29 healthy volunteers in order to assess the damaging action on the gastroduodenal mucosa induced by an inactive form of NSAIDs (as prodrug) in comparison with diclofenac Na (D) .Subjects received eit
Publikováno v:
Speaker abstracts 2001.
Background Ectopic ossifications (EO) following total hip replacement are possible and known post-operative complications, developing in about 60% of patients during the first 4–12 weeks after implantation. There is no treatment but surgery, theref
Autor:
J. Esprito Santo, M Viana Queiroz, J. Melo Gomes, J.A. Pereira da Silva, J. C. Teixeira Da Costa
Publikováno v:
Current Medical Research and Opinion. 8:524-530
Forty out-patients with acute 'flare' of chronic rheumatoid arthritis were treated orally with either 150 mg proglumetacin or 250 mg naproxen twice daily over 3 weeks, according to a randomized, double-blind design. Before and after 1 and 3 weeks of
Publikováno v:
Scandinavian Journal of Rheumatology. 17:318-324
The cyclooxygenase pathway promotes formation of an endoperoxide that is the precursor of prostaglandins (PG), thromboxanes (Tx) and prostacyclins (PGI2), all of which have important biologic activities. In this study, we examined the ability of huma