Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Profile Study"'
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
BackgroundSince the end of 2019, Corona Virus Disease 2019, also known as COVID-19, has broken out in various countries. However, the change of China's COVID-19 prevention and control policy and the sharp increase in the number of infected people are
Externí odkaz:
https://doaj.org/article/931e132c9f8943df9c95be703080325e
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1325 (2023)
Since the discovery of cisplatin, the search for metal-based compounds with therapeutic potential has been a challenge for the scientific community. In this landscape, thiosemicarbazones and their metal derivatives represent a good starting point for
Externí odkaz:
https://doaj.org/article/7b14e537149b43bdac93025902010fdd
Akademický článek
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Autor:
Huynh-Le, Minh-Phuong, Karunamuni, Roshan, Fan, Chun Chieh, Asona, Lui, Thompson, Wesley K, Martinez, Maria Elena, Eeles, Rosalind A, Kote-Jarai, Zsofia, Muir, Kenneth R, Lophatananon, Artitaya, Schleutker, Johanna, Pashayan, Nora, Batra, Jyotsna, Grönberg, Henrik, Neal, David E, Nordestgaard, Børge G, Tangen, Catherine M, MacInnis, Robert J, Wolk, Alicja, Albanes, Demetrius, Haiman, Christopher A, Travis, Ruth C, Blot, William J, Stanford, Janet L, Mucci, Lorelei A, West, Catharine ML, Nielsen, Sune F, Kibel, Adam S, Cussenot, Olivier, Berndt, Sonja I, Koutros, Stella, Sørensen, Karina Dalsgaard, Cybulski, Cezary, Grindedal, Eli Marie, Menegaux, Florence, Park, Jong Y, Ingles, Sue A, Maier, Christiane, Hamilton, Robert J, Rosenstein, Barry S, Lu, Yong-Jie, Watya, Stephen, Vega, Ana, Kogevinas, Manolis, Wiklund, Fredrik, Penney, Kathryn L, Huff, Chad D, Teixeira, Manuel R, Multigner, Luc, Leach, Robin J, Brenner, Hermann, John, Esther M, Kaneva, Radka, Logothetis, Christopher J, Neuhausen, Susan L, De Ruyck, Kim, Ost, Piet, Razack, Azad, Newcomb, Lisa F, Fowke, Jay H, Gamulin, Marija, Abraham, Aswin, Claessens, Frank, Castelao, Jose Esteban, Townsend, Paul A, Crawford, Dana C, Petrovics, Gyorgy, Van Schaik, Ron HN, Parent, Marie-Élise, Hu, Jennifer J, Zheng, Wei, UKGPCS Collaborators, APCB (Australian Prostate Cancer BioResource), NC-LA PCaP Investigators, IMPACT Study Steering Committee And Collaborators, Canary PASS Investigators, Profile Study Steering Committee, PRACTICAL Consortium, Mills, Ian G, Andreassen, Ole A, Dale, Anders M, Seibert, Tyler M
Publikováno v:
Prostate cancer and prostatic diseases, vol 25, iss 4
Funder: University of California (#C21CR2060), the Prostate Cancer Foundation
Funder: Research Council of Norway (#223273), KG Jebsen Stiftelsen, and South East Norway Health Authority
BACKGROUND: Prostate cancer risk stratification using s
Funder: Research Council of Norway (#223273), KG Jebsen Stiftelsen, and South East Norway Health Authority
BACKGROUND: Prostate cancer risk stratification using s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e45ca1a6a58ee0a8bd673a6a4c4fef
https://escholarship.org/uc/item/00p470cn
https://escholarship.org/uc/item/00p470cn
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Toby M. Maher
Publikováno v:
European Respiratory Review, Vol 22, Iss 128, Pp 148-152 (2013)
Despite major advances in the understanding of the pathogenesis of idiopathic pulmonary fibrosis (IPF), diagnosis and management of the condition continue to pose significant challenges. Clinical management of IPF remains unsatisfactory due to limite
Externí odkaz:
https://doaj.org/article/2021b6b740ed4f8f9f2d86d7eb2a5739
Autor:
Karunamuni, Roshan A, Huynh-Le, Minh-Phuong, Fan, Chun C, Thompson, Wesley, Eeles, Rosalind A, Kote-Jarai, Zsofia, Muir, Kenneth, Lophatananon, Artitaya, UKGPCS collaborators, Schleutker, Johanna, Pashayan, Nora, Batra, Jyotsna, APCB BioResource (Australian Prostate Cancer BioResource), Grönberg, Henrik, Walsh, Eleanor I, Turner, Emma L, Lane, Athene, Martin, Richard M, Neal, David E, Donovan, Jenny L, Hamdy, Freddie C, Nordestgaard, Børge G, Tangen, Catherine M, MacInnis, Robert J, Wolk, Alicja, Albanes, Demetrius, Haiman, Christopher A, Travis, Ruth C, Stanford, Janet L, Mucci, Lorelei A, West, Catharine ML, Nielsen, Sune F, Kibel, Adam S, Wiklund, Fredrik, Cussenot, Olivier, Berndt, Sonja I, Koutros, Stella, Sørensen, Karina Dalsgaard, Cybulski, Cezary, Grindedal, Eli Marie, Park, Jong Y, Ingles, Sue A, Maier, Christiane, Hamilton, Robert J, Rosenstein, Barry S, Vega, Ana, IMPACT Study Steering Committee and Collaborators, Kogevinas, Manolis, Penney, Kathryn L, Teixeira, Manuel R, Brenner, Hermann, John, Esther M, Kaneva, Radka, Logothetis, Christopher J, Neuhausen, Susan L, Razack, Azad, Newcomb, Lisa F, Canary PASS Investigators, Gamulin, Marija, Usmani, Nawaid, Claessens, Frank, Gago-Dominguez, Manuela, Townsend, Paul A, Roobol, Monique J, Zheng, Wei, Profile Study Steering Committee, Mills, Ian G, Andreassen, Ole A, Dale, Anders M, Seibert, Tyler M, PRACTICAL Consortium
Publikováno v:
Prostate cancer and prostatic diseases, vol 24, iss 2
BackgroundPolygenic hazard scores (PHS) can identify individuals with increased risk of prostate cancer. We estimated the benefit of additional SNPs on performance of a previously validated PHS (PHS46).Materials and method180 SNPs, shown to be previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4e963e330b57cf89dda5bd1bde2ea1f3
https://escholarship.org/uc/item/8mn2q2cr
https://escholarship.org/uc/item/8mn2q2cr
Autor:
Florence Menegaux, William J. Blot, Henrik Grönberg, Luc Multigner, Sune F. Nielsen, Stella Koutros, Frank Claessens, Manuela Gago-Dominguez, Kathryn L. Penney, Tyler M. Seibert, Cezary Cybulski, Jennifer J. Hu, Hermann Brenner, Radka Kaneva, Sue A. Ingles, Catherine M. Tangen, Ian G. Mills, Janet L. Stanford, Karina Dalsgaard Sørensen, Ruth C. Travis, Marie-Élise Parent, Monique J. Roobol, Nora Pashayan, Jyotsna Batra, Maria Elena Martinez, Anders M. Dale, Wei Zheng, Kay-Tee Khaw, Chad D. Huff, Chun Chieh Fan, Paul A. Townsend, Kim De Ruyck, Yong-Jie Lu, Eli Marie Grindedal, Hardev Pandha, Sonja I. Berndt, Susan L. Neuhausen, Alicja Wolk, Apcb, Wesley K. Thompson, Maureen Sanderson, Demetrius Albanes, Stephen N. Thibodeau, Christiane Maier, Kenneth Muir, Robin J. Leach, Børge G. Nordestgaard, Ole A. Andreassen, Fredrik Wiklund, Graham G. Giles, Zsofia Kote-Jarai, Catharine M L West, Minh-Phuong Huynh-Le, Manolis Kogevinas, Manuel R. Teixeira, Jong Y. Park, Johanna Schleutker, Marija Gamulin, Freddie C. Hamdy, William S. Bush, Barry S. Rosenstein, Stephen Watya, Roshan Karunamuni, Richard M. Martin, Nc-La PCaP Investigators, Ana Vega, Adam S. Kibel, Lisa A. Cannon-Albright, Azad Hassan Abdul Razack, Esther M. John, Christopher J. Logothetis, Jay H. Fowke, Nawaid Usmani, David E. Neal, Canary Pass Investigators, Rosalind A. Eeles, Robert J. Hamilton, Lisa F. Newcomb, Jenny L Donovan, Olivier Cussenot, Lorelei A. Mucci
Publikováno v:
Nature communications, vol 12, iss 1
APCB (Australian Prostate Cancer BioResource), NC-LA PCaP Investigators, The IMPACT Study Steering Committee and Collaborators, Canary PASS Investigators, The Profile Study Steering Committee, The Practical Consortium & UKGPCS Collaborators 2021, ' Polygenic hazard score is associated with prostate cancer in multi-ethnic populations ', Nature Communications, vol. 12, no. 1, 1236 . https://doi.org/10.1038/s41467-021-21287-0
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Huynh-Le, M-P, Fan, C C, Karunamuni, R, Thompson, W K, Martinez, M E, Eeles, R A, Kote-Jarai, Z, Muir, K, Schleutker, J, Pashayan, N, Batra, J, Grönberg, H, Neal, D E, Donovan, J L, Hamdy, F C, Martin, R M, Nielsen, S F, Nordestgaard, B G, Wiklund, F, Tangen, C M, Giles, G G, Wolk, A, Albanes, D, Travis, R C, Blot, W J, Zheng, W, Sanderson, M, Stanford, J L, Mucci, L A, West, C M L, Kibel, A S, Cussenot, O, Berndt, S I, Koutros, S, Sørensen, K D, Cybulski, C, Grindedal, E M, Menegaux, F, Khaw, K-T, Park, J Y, Ingles, S A, Maier, C, Hamilton, R J, Thibodeau, S N, Rosenstein, B S, Lu, Y-J, Watya, S, Vega, A, Kogevinas, M, Penney, K L & UKGPCS collaborators 2021, ' Polygenic hazard score is associated with prostate cancer in multi-ethnic populations ', Nature Communications, vol. 12, no. 1, 1236 . https://doi.org/10.1038/s41467-021-21287-0
UKGPCS Collaborators 2021, ' Polygenic hazard score is associated with prostate cancer in multi-ethnic populations ', Nature Communications, vol. 12, no. 1, 1236 . https://doi.org/10.1038/s41467-021-21287-0
Huynh-Le, M-P, Fan, C C, Karunamuni, R, Thompson, W K, Martinez, M E, Eeles, R A, Kote-Jarai, Z, Muir, K, Schleutker, J, Pashayan, N, Batra, J, Grönberg, H, Neal, D E, Donovan, J L, Hamdy, F C, Martin, R M, Nielsen, S F, Nordestgaard, B G, Wiklund, F, Tangen, C M, Giles, G G, Wolk, A, Albanes, D, Travis, R C, Blot, W J, Zheng, W, Sanderson, M, Stanford, J L, Mucci, L A, West, C M L, Kibel, A S, Cussenot, O, Berndt, S I, Koutros, S, Sørensen, K D, Cybulski, C, Grindedal, E M, Menegaux, F, Khaw, K-T, Park, J Y, Ingles, S A, Maier, C, Hamilton, R J, Thibodeau, S N, Rosenstein, B S, Lu, Y-J, Watya, S, Vega, A, Kogevinas, M, Penney, K L, Huff, C, Teixeira, M R, Multigner, L, Leach, R J, Cannon-Albright, L, Brenner, H, John, E M, Kaneva, R, Logothetis, C J, Neuhausen, S L, De Ruyck, K, Pandha, H, Razack, A, Newcomb, L F, Fowke, J H, Gamulin, M, Usmani, N, Claessens, F, Gago-Dominguez, M, Townsend, P A, Bush, W S, Roobol, M J, Parent, M-É, Hu, J J, Mills, I G, Andreassen, O A, Dale, A M, Seibert, T M, collaborators, UKGPCS, BioResource), APCB A P C, Investigators, NC-LA PC, Collaborators, T IMPACT S S C A, Investigators, C PASS, Committee, T P S S & Consortium, T PRACTICAL 2021, ' Polygenic hazard score is associated with prostate cancer in multi-ethnic populations ', Nature Communications, vol. 12, 1236 . https://doi.org/10.1038/s41467-021-21287-0
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.1236. ⟨10.1038/s41467-021-21287-0⟩
Nature Communications, 2021, 12 (1), pp.1236. ⟨10.1038/s41467-021-21287-0⟩
Nature Communications, 12(1):1236. Nature Publishing Group
Huynh-Le, M-P, Donovan, J L, Martin, R M, Seibert, T M & al., E 2021, ' Polygenic hazard score is associated with prostate cancer in multi-ethnic populations ', Nature Communications, vol. 12, no. 1, 1236, pp. 1236 (2021) . https://doi.org/10.1038/s41467-021-21287-0
APCB (Australian Prostate Cancer BioResource), NC-LA PCaP Investigators, The IMPACT Study Steering Committee and Collaborators, Canary PASS Investigators, The Profile Study Steering Committee, The Practical Consortium & UKGPCS Collaborators 2021, ' Polygenic hazard score is associated with prostate cancer in multi-ethnic populations ', Nature Communications, vol. 12, no. 1, 1236 . https://doi.org/10.1038/s41467-021-21287-0
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Huynh-Le, M-P, Fan, C C, Karunamuni, R, Thompson, W K, Martinez, M E, Eeles, R A, Kote-Jarai, Z, Muir, K, Schleutker, J, Pashayan, N, Batra, J, Grönberg, H, Neal, D E, Donovan, J L, Hamdy, F C, Martin, R M, Nielsen, S F, Nordestgaard, B G, Wiklund, F, Tangen, C M, Giles, G G, Wolk, A, Albanes, D, Travis, R C, Blot, W J, Zheng, W, Sanderson, M, Stanford, J L, Mucci, L A, West, C M L, Kibel, A S, Cussenot, O, Berndt, S I, Koutros, S, Sørensen, K D, Cybulski, C, Grindedal, E M, Menegaux, F, Khaw, K-T, Park, J Y, Ingles, S A, Maier, C, Hamilton, R J, Thibodeau, S N, Rosenstein, B S, Lu, Y-J, Watya, S, Vega, A, Kogevinas, M, Penney, K L & UKGPCS collaborators 2021, ' Polygenic hazard score is associated with prostate cancer in multi-ethnic populations ', Nature Communications, vol. 12, no. 1, 1236 . https://doi.org/10.1038/s41467-021-21287-0
UKGPCS Collaborators 2021, ' Polygenic hazard score is associated with prostate cancer in multi-ethnic populations ', Nature Communications, vol. 12, no. 1, 1236 . https://doi.org/10.1038/s41467-021-21287-0
Huynh-Le, M-P, Fan, C C, Karunamuni, R, Thompson, W K, Martinez, M E, Eeles, R A, Kote-Jarai, Z, Muir, K, Schleutker, J, Pashayan, N, Batra, J, Grönberg, H, Neal, D E, Donovan, J L, Hamdy, F C, Martin, R M, Nielsen, S F, Nordestgaard, B G, Wiklund, F, Tangen, C M, Giles, G G, Wolk, A, Albanes, D, Travis, R C, Blot, W J, Zheng, W, Sanderson, M, Stanford, J L, Mucci, L A, West, C M L, Kibel, A S, Cussenot, O, Berndt, S I, Koutros, S, Sørensen, K D, Cybulski, C, Grindedal, E M, Menegaux, F, Khaw, K-T, Park, J Y, Ingles, S A, Maier, C, Hamilton, R J, Thibodeau, S N, Rosenstein, B S, Lu, Y-J, Watya, S, Vega, A, Kogevinas, M, Penney, K L, Huff, C, Teixeira, M R, Multigner, L, Leach, R J, Cannon-Albright, L, Brenner, H, John, E M, Kaneva, R, Logothetis, C J, Neuhausen, S L, De Ruyck, K, Pandha, H, Razack, A, Newcomb, L F, Fowke, J H, Gamulin, M, Usmani, N, Claessens, F, Gago-Dominguez, M, Townsend, P A, Bush, W S, Roobol, M J, Parent, M-É, Hu, J J, Mills, I G, Andreassen, O A, Dale, A M, Seibert, T M, collaborators, UKGPCS, BioResource), APCB A P C, Investigators, NC-LA PC, Collaborators, T IMPACT S S C A, Investigators, C PASS, Committee, T P S S & Consortium, T PRACTICAL 2021, ' Polygenic hazard score is associated with prostate cancer in multi-ethnic populations ', Nature Communications, vol. 12, 1236 . https://doi.org/10.1038/s41467-021-21287-0
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.1236. ⟨10.1038/s41467-021-21287-0⟩
Nature Communications, 2021, 12 (1), pp.1236. ⟨10.1038/s41467-021-21287-0⟩
Nature Communications, 12(1):1236. Nature Publishing Group
Huynh-Le, M-P, Donovan, J L, Martin, R M, Seibert, T M & al., E 2021, ' Polygenic hazard score is associated with prostate cancer in multi-ethnic populations ', Nature Communications, vol. 12, no. 1, 1236, pp. 1236 (2021) . https://doi.org/10.1038/s41467-021-21287-0
Genetic models for cancer have been evaluated using almost exclusively European data, which could exacerbate health disparities. A polygenic hazard score (PHS1) is associated with age at prostate cancer diagnosis and improves screening accuracy in Eu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2599822b66c464be56baaf75fc349c7
https://escholarship.org/uc/item/6g41x9nq
https://escholarship.org/uc/item/6g41x9nq
Publikováno v:
مجلة كلية الطب, Vol 47, Iss 1 (2005)
Background: The accumulation of the lipid in the vascular smooth muscle cell within the arterial intima is a key process of the pathogenesis of atherosclerosis. Atherosclerosis is a degenerative disease of blood vessels leading to stroke. Materials &
Externí odkaz:
https://doaj.org/article/c94e2b3782d245edaf727a188f3f5f60