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of 860
pro vyhledávání: '"Prodynorphin"'
Autor:
Xing Wu, Zihao Zhang, Yijie Li, Yudian Zhao, Yangguang Ren, Yixiang Tian, Meng Hou, Yulong Guo, Qi Li, Weihua Tian, Ruirui Jiang, Yanhua Zhang, Yujie Gong, Hong Li, Guoxi Li, Xiaojun Liu, Xiangtao Kang, Donghua Li, Yadong Tian
Publikováno v:
Poultry Science, Vol 103, Iss 7, Pp 103820- (2024)
ABSTRACT: The “KNDy neurons” located in the hypothalamic arcuate nucleus (ARC) of mammals are known to co-express kisspeptin, neurokinin B (NKB), and dynorphin (DYN), and have been identified as key mediators of the feedback regulation of steroid
Externí odkaz:
https://doaj.org/article/c600ee34a05f42818913234cab784feb
Publikováno v:
Frontiers in Neural Circuits, Vol 18 (2024)
Olfactory dysfunctions decrease daily quality of life (QOL) in part by reducing the pleasure of eating. Olfaction plays an essential role in flavor sensation and palatability. The decreased QOL due to olfactory dysfunction is speculated to result fro
Externí odkaz:
https://doaj.org/article/386d2df33f0049d1988214758c047fa6
Autor:
Zhou, Shudi
Indiana University-Purdue University Indianapolis (IUPUI)
Currently, changes to endogenous opioid circuits in various pain modalities, including surgical and neuropathic pain, remain unclear. Dynorphin, which is released by prodynorphin-expressi
Currently, changes to endogenous opioid circuits in various pain modalities, including surgical and neuropathic pain, remain unclear. Dynorphin, which is released by prodynorphin-expressi
Externí odkaz:
https://hdl.handle.net/1805/30794
Publikováno v:
Neurobiology of Pain, Vol 13, Iss , Pp 100121- (2023)
The medial prefrontal cortex (mPFC) consists of a heterogeneous population of neurons that respond to painful stimuli, and our understanding of how different pain models alter these specific mPFC cell types remains incomplete. A distinct subpopulatio
Externí odkaz:
https://doaj.org/article/cb772e4657884eb0aaac609915ce5282
Publikováno v:
Frontiers in Neural Circuits, Vol 16 (2022)
The olfactory tubercle (OT) is a striatal region that receives olfactory inputs. mRNAs of prodynorphin (Pdyn) and preproenkephalin (Penk), precursors of dynorphins and enkephalins, respectively, are strongly expressed in the striatum. Both produce op
Externí odkaz:
https://doaj.org/article/c0e38f9fb97946fa992f5b90e8bfca2d
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Background Microglia-mediated neuroinflammation is associated with epilepsy. Switching microglial polarization from the pro-inflammatory M1 phenotype to the anti-inflammatory M2 phenotype represents a novel therapeutic strategy for mitigatin
Externí odkaz:
https://doaj.org/article/a399415d79bc4943b02f6e35798f4f2b
Autor:
Shinya Kasai, Daisuke Nishizawa, Junko Hasegawa, Ken-ichi Fukuda, Tatsuya Ichinohe, Makoto Nagashima, Masakazu Hayashida, Kazutaka Ikeda
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Short tandem repeats (STRs) and variable number of tandem repeats (VNTRs) that have been identified at approximately 0.7 and 0.5 million loci in the human genome, respectively, are highly multi-allelic variations rather than single-nucleotide polymor
Externí odkaz:
https://doaj.org/article/f2538b7189e04327b3b63d60d54d664a
Akademický článek
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Publikováno v:
BMC Psychiatry, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Prodynorphin (PDYN) gene polymorphisms have been linked with opioid dependence (OD) with conflicting outcomes, the aim of this study is to synthesize the existing evidence of the association between PDYN polymorphisms and OD susce
Externí odkaz:
https://doaj.org/article/3c8b46677f514391949f171dc41fcfd4
Publikováno v:
Neuropsychiatric Disease and Treatment, Vol Volume 14, Pp 1025-1034 (2018)
Vadim Yuferov,* Eduardo R Butelman,* Mary Jeanne Kreek Laboratory of the Biology of Addictive Diseases, The Rockefeller University, New York, NY, USA *These authors contributed equally to this work Background: Cannabis use disorders (CUDs) cause subs
Externí odkaz:
https://doaj.org/article/42dd4694a66a4dffb0e735f7f82b500b