Zobrazeno 1 - 10
of 481
pro vyhledávání: '"Prochownik P"'
Autor:
Paweł Prochownik, Klaudia Bielecka, Tadeusz Przewłocki, Zuzanna Sachajko, Urszula Gancarczyk, Piotr Wilkołek, Michał Tworek, Piotr Podolec, Larysa Bielecka, Monika Komar
Publikováno v:
Advances in Interventional Cardiology, Vol 20, Iss 3, Pp 338-344 (2024)
Externí odkaz:
https://doaj.org/article/a8421768003343489171aafe3d39f036
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Tumor cells reprogram their metabolism to produce specialized metabolites that both fuel their own growth and license tumor immune evasion. However, the relationships between these functions remain poorly understood. Here, we report CRISPR s
Externí odkaz:
https://doaj.org/article/398b801bce3444af957970672364bf04
Publikováno v:
Advanced Science, Vol 11, Iss 43, Pp n/a-n/a (2024)
Abstract Certain metabolites in the tumor microenvironment (TME) can alter innate immunity. Here, it is shown how phosphomevalonate kinase (PMVK) allows hepatocellular carcinoma (HCC) cells to overcome the anti‐tumor immunity mediated by CD8+ T cel
Externí odkaz:
https://doaj.org/article/ecea4a33efd04ca28e1c8287cd68d383
Autor:
Huabo Wang, Taylor Stevens, Jie Lu, Alexander Roberts, Clinton Van't Land, Radhika Muzumdar, Zhenwei Gong, Jerry Vockley, Edward V. Prochownik
Publikováno v:
Advanced Science, Vol 11, Iss 34, Pp n/a-n/a (2024)
Abstract The “Mlx” and “Myc” transcription factor networks cross‐communicate and share many common gene targets. Myc's activity depends upon its heterodimerization with Max, whereas the Mlx Network requires that the Max‐like factor Mlx as
Externí odkaz:
https://doaj.org/article/21d46c4a8a1c4ee19059c58c19da19c0
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 5, Pp 1122-1127 (2023)
Many human cancers carry missense mutations in or deletions of the tumor protein 53 (TP53) tumor suppressor gene. TP53’s product, p53 regulates many biological processes, including cell metabolism. Cholesterol is a key lipid needed for the maintena
Externí odkaz:
https://doaj.org/article/aa8930e9170b474d89666830e6a450e5
Autor:
Kelly R. Moore, Sarah A. Stotz, Martha Ann Terry, Ellen W. Seely, Kelly Gonzales, Gale Marshall, Kristen J. Nadeau, Aletha Akers, Yesenia Garcia-Reyes, Denise Charron-Prochownik, For the Stopping GDM Study Group
Publikováno v:
BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background American Indians and Alaska Natives (AI/AN) are disproportionately affected by adolescent obesity, adolescent pregnancy and gestational diabetes mellitus (GDM). GDM is associated with increased risk for perinatal death, obesity, a
Externí odkaz:
https://doaj.org/article/728921d6e7054a9498dbdb8db7442e5b
Akademický článek
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Publikováno v:
Plants, Vol 13, Iss 11, p 1515 (2024)
Sprouts’ consumption has become popular due to their wide availability, easy cultivation process, and proven biological activity. Moreover, stress factors, such as limited access to light or disturbed gravity during growth, may contribute to the in
Externí odkaz:
https://doaj.org/article/9952a0bccfbb4d2495fa81edf72bfd68
Autor:
Jianhong Zhao, Xiaojun Zhou, Baoxiang Chen, Mingzhu Lu, Genxin Wang, Nagarajan Elumalai, Chenhui Tian, Jinmiao Zhang, Yanliang Liu, Zhiqiang Chen, Xinyi Zhou, Mingzhi Wu, Mengjiao Li, Edward V. Prochownik, Ali Tavassoli, Congqing Jiang, Youjun Li
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-15 (2023)
Abstract The metabolic pathways through which p53 functions as a potent tumor suppressor are incompletely understood. Here we report that, by associating with the Vitamin D receptor (VDR), p53 induces numerous genes encoding enzymes for peroxisomal f
Externí odkaz:
https://doaj.org/article/e6dcfc904fcf4acebbe5587ed3ec5f0d
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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