Zobrazeno 1 - 10
of 3 244
pro vyhledávání: '"Prnp"'
Autor:
Julia Sala-Jarque, Vanessa Gil, Pol Andrés-Benito, Inés Martínez-Soria, Pol Picón-Pagès, Félix Hernández, Jesús Ávila, José Luis Lanciego, Mario Nuvolone, Adriano Aguzzi, Rosalina Gavín, Isidro Ferrer, José Antonio del Río
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The cellular prion protein (PrPC) plays many roles in the developing and adult brain. In addition, PrPC binds to several amyloids in oligomeric and prefibrillar forms and may act as a putative receptor of abnormal misfolded protein species.
Externí odkaz:
https://doaj.org/article/2f78e00735454e27858d150cc64c59b9
Autor:
Johann Laubier, Anne Van De Wiele, Aurélie Barboiron, Denis Laloë, Christine Saint-Andrieux, Johan Castille, Emma Meloni, Sonja Ernst, Maryline Pellerin, Sandrine Floriot, Nathalie Daniel-Carlier, Bruno Passet, Joël Merlet, Hélène Verheyden, Vincent Béringue, Olivier Andréoletti, Fiona Houston, Jean-Luc Vilotte, Vincent Bourret, Katayoun Moazami-Goudarzi
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-14 (2024)
Abstract The recent emergence of chronic wasting disease (CWD) in Europe has become a new public health risk for monitoring of wild and farmed cervids. This disease, due to prions, has proliferated in North America in a contagious manner. In several
Externí odkaz:
https://doaj.org/article/d6f18d27740f45e5b27dd81a0318ad5e
Publikováno v:
Неврология, нейропсихиатрия, психосоматика, Vol 16, Iss 4, Pp 68-75 (2024)
This article presents a clinical case of Gerstmann–Sträussler–Scheinker syndrome (GSS) – a progressive inherited prion disease with an extremely rare phenotype that changed dynamically during the course of the disease and eventually led to the
Externí odkaz:
https://doaj.org/article/b4cd9b80f3394588a08c657c27d40836
Autor:
Carlotta Ferrari, Chiara Punturiero, Raffaella Milanesi, Andrea Delledonne, Alessandro Bagnato, Maria G. Strillacci
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-10 (2024)
Abstract Scrapie is a transmissible spongiform encephalopathy affecting sheep and goats. The prion protein-encoding gene (PRNP) plays a crucial role in determining susceptibility and resistance to scrapie. At the European level, surveillance of scrap
Externí odkaz:
https://doaj.org/article/5ae2d58e88c248f2b0dfce9e73242289
Autor:
Sonja Ernst, Agata Piestrzyńska-Kajtoch, Jörn Gethmann, Małgorzata Natonek-Wiśniewska, Balal Sadeghi, Miroslaw P. Polak, Markus Keller, Dolores Gavier-Widén, Katayoun Moazami-Goudarzi, Fiona Houston, Martin H. Groschup, Christine Fast
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-17 (2024)
Abstract The structure of cellular prion proteins encoded by the prion protein gene (PRNP) impacts susceptibility to transmissible spongiform encephalopathies, including chronic wasting disease (CWD) in deer. The recent emergence of CWD in Northern E
Externí odkaz:
https://doaj.org/article/e948b18743cb4d5abc36dd15412c251c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
BackgroundPrion protein gene (PRNP) is widely expressed in a variety of tissues. Although the roles of PRNP in several cancers have been investigated, no pan-cancer analysis has revealed its relationship with tumorigenesis and immunity.MethodsCompreh
Externí odkaz:
https://doaj.org/article/741c370ddd1d4527a565fe3c3a8978ad
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
KANNO is a new human blood group that was recently discovered. The KANNO antigen shares the PRNP gene with the prion protein and the prion protein E219K polymorphism determines the presence or absence of the KANNO antigen and the development of anti-
Externí odkaz:
https://doaj.org/article/cd2f800fee0a44c2994719947aa74400
Autor:
Emily A. Wright, Madison B. Reddock, Emma K. Roberts, Yoseph W. Legesse, Gad Perry, Robert D. Bradley
Publikováno v:
PeerJ, Vol 12, p e17552 (2024)
Transmissible spongiform encephalopathies (TSEs) are a fatal neurogenerative disease that include Creutzfeldt–Jakob disease in humans, scrapie in sheep and goats, bovine spongiform encephalopathy (BSE), and several others as well as the recently de
Externí odkaz:
https://doaj.org/article/9bf4ad34456a43a99b98f40155a74a4b
Autor:
Paolina Crocco, Francesco De Rango, Francesco Bruno, Antonio Malvaso, Raffaele Maletta, Amalia C. Bruni, Giuseppe Passarino, Giuseppina Rose, Serena Dato
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e31624- (2024)
The Forkhead box P2 (FOXP2) is an evolutionary conserved transcription factor involved in the maintenance of neuronal networks, implicated in language disorders. Some evidence suggests a possible link between FOXP2 genetic variability and frontotempo
Externí odkaz:
https://doaj.org/article/e972a711805442169ef3c2c55539b42d
Autor:
Rizwana Rasheed, Jamil Ahmad, Tanveer Hussain, Abdul Wajid, Sara Nudhani, Muneeb M. Musthafa, Faiz MMT Marikar
Publikováno v:
Ukrainian Journal of Veterinary and Agricultural Sciences, Vol 6, Iss 3, Pp 3-7 (2023)
Prion diseases are a type of neurodegenerative disorder caused by the transmission of specific pathogens containing prion proteins. Due to the unique structural characteristics of Prion proteins (PrP), which differ from other types of proteins, the e
Externí odkaz:
https://doaj.org/article/b47f37e5a2f64c2a95ccaffd0b604f08