Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Priyatham Gorjala"'
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257984 (2021)
Prostate cancer is the second leading cause of cancer related death in American men. Several therapies have been developed to treat advanced prostate cancer, but these therapies often have severe side effects. To improve the outcome with fewer side e
Externí odkaz:
https://doaj.org/article/189da2492d3d4aeea0a10690886dd5d5
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background Neoplastic cells proliferate rapidly and obtain requisite building blocks by reprogramming metabolic pathways that favor growth. Previously, we observed that prostate cancer cells uptake and store lipids in the form of lipid dropl
Externí odkaz:
https://doaj.org/article/77485f3226b84c4c9cc7e440c4281e0c
Publikováno v:
Cancers, Vol 12, Iss 4, p 989 (2020)
Androgen receptor signaling is crucial for prostate cancer growth and is positively regulated in part by intratumoral CYP3A5. As African American (AA) men often carry the wild type CYP3A5 and express high levels of CYP3A5 protein, we blocked the wild
Externí odkaz:
https://doaj.org/article/4f1dcc950d3a42ec971c2c6859f12384
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132105 (2015)
Profiling cellular proteome is critical to understanding signal integration during cell fate determination. In this study, the capability of capillary isoelectric focusing (cIEF) immunoassays to detect post-translational modifications (PTM) of protei
Externí odkaz:
https://doaj.org/article/31b4867d89ea4fe4a35a0449345dac31
Prostate cancer is the second leading cause of cancer related death in American men. Several therapies have been developed to treat advanced prostate cancer, but these therapies often have severe side effects. To improve the outcome with fewer side e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d35abb3ef4514ddf8303691073201f0
https://doi.org/10.1101/2021.05.06.442999
https://doi.org/10.1101/2021.05.06.442999
Autor:
Madhavi Bathina, Stanley Hooker, Ranjana Mitra, Leanne Woods-Burnham, K. Sean Kimbro, Rick A. Kittles, Stacy M. Lloyd, Larisa Nonn, Priyatham Gorjala
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Background: Given the scarcity of cell lines from underrepresented populations, it is imperative that genetic ancestry for these cell lines is characterized. Consequences of cell line mischaracterization include squandered resources and publication r
Publikováno v:
Cell Proliferation. 49:698-709
Objectives Beryllium salts (here, beryllium sulphate) can produce a cytostatic effect in some cell types. The basis for this effect may include increased expression of proliferation inhibitors, reduced expression of proliferation promoters, or both.
Publikováno v:
Cancer Research. 80:2467-2467
Background: Previously we have demonstrated that CYP3A5 stimulates prostate cancer cell growth by promoting AR activation and downstream signaling. We further investigated the mechanism of CYP3A5's interaction with the AR-HSP90 complex known to regul
Publikováno v:
Cancer Research. 80:3475-3475
Background: Previous research has revealed that the androgen receptor (AR), which upon activation goes to the nucleus, is the driving force of prostate cancer growth. Once activated, AR promotes transcription of genes responsible for promoting cancer
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 29:B017-B017
Introduction: African-American men (AA) often present with aggressive castration-resistant prostate cancer (CRPC), due to highly active androgen receptor (AR). AR is a ligand-activated transcription factor that promotes expression of genes responsibl