Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Priyanka Suryadevara"'
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 14, Iss 2, Pp ED07-ED09 (2020)
Waldenström’s Macroglobulinemia (WM) is a chronic B-cell lymphoproliferative disorder with bone marrow infiltration with small lymphocytes, lymphoplasmacytoid cells and plasma cells and presence of IgM paraprotein in the serum. We report here a ca
Externí odkaz:
https://doaj.org/article/afb928c5ebe74ec99a17a8419c8cb104
Autor:
Vijay Soni, Sandeep Upadhayay, Priyanka Suryadevara, Ganesh Samla, Archana Singh, Perumal Yogeeswari, Dharmarajan Sriram, Vinay Kumar Nandicoori
Publikováno v:
PLoS Pathogens, Vol 11, Iss 10, p e1005235 (2015)
M. tuberculosis N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmUMtb) is a bi-functional enzyme engaged in the synthesis of two metabolic intermediates N-acetylglucosamine-1-phosphate (GlcNAc-1-P) and UDP-GlcNAc, catalyzed by the C- and N-term
Externí odkaz:
https://doaj.org/article/315b575a80a3435189ae1e616c3d39ba
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 14, Iss 2, Pp ED07-ED09 (2020)
Waldenström’s Macroglobulinemia (WM) is a chronic B-cell lymphoproliferative disorder with bone marrow infiltration with small lymphocytes, lymphoplasmacytoid cells and plasma cells and presence of IgM paraprotein in the serum. We report here a ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b99404ae2c53fd468756f67d28b6db
https://doi.org/10.7860/jcdr/2020/42892.13521
https://doi.org/10.7860/jcdr/2020/42892.13521
Autor:
Perumal Yogeeswari, Vinay Kumar Nandicoori, Dharmarajan Sriram, Parthiban Brindha Devi, Vijay Soni, Priyanka Suryadevara
Publikováno v:
Current Topics in Medicinal Chemistry. 16:978-995
The highly persistent nature of Mycobacterium tuberculosis can be attributed to its lipophilic cell wall which acts as a major barrier in the process of drug discovery against tuberculosis. Glutamine synthetase plays a major role in nitrogen metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782787c6018dd3ca10f1f7b7e48cd30f
https://doi.org/10.2174/1568026615666150825142726
https://doi.org/10.2174/1568026615666150825142726
Autor:
Renuka Janupally, Vijay Soni, Hasitha Shilpa Anantaraju, Dharmarajan Sriram, Priyanka Suryadevara, Jogula Sridhar, Jonnalagadda Padma Sridevi, Perumal Yogeeswari
Publikováno v:
European Journal of Pharmaceutical Sciences. 72:81-92
Mycobacterium tuberculosis (Mtb) topoisomerase I (Topo I), involved in the relaxation of negatively supercoiled DNA, plays an important role in the viability of pathogen Mtb. Being one of the most significant enzymes; it also takes part in crucial bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85375baa8481f7c3b5518d8f4b62b15
https://doi.org/10.1016/j.ejps.2015.02.017
https://doi.org/10.1016/j.ejps.2015.02.017
Autor:
Pushkar Kulkarni, Perumal Yogeeswari, Parthiban Brindha Devi, Variam Ullas Jeankumar, Renuka Janupally, Bhramam Medepi, Dharmarajan Sriram, Priyanka Suryadevara
Publikováno v:
Chemical Biology & Drug Design. 86:918-925
DNA topoisomerases are well-validated targets in micro-organisms. DNA gyraseB is one of the most important enzymes among them as per their clinical importance. In earlier study, a novel lead 4-((4-(furan-2-carboxamido)phenyl)amino)-4-oxobutanoic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553799da287316b8ff69b98750f00883
https://doi.org/10.1111/cbdd.12529
https://doi.org/10.1111/cbdd.12529
Autor:
Vijay Soni, Dharmarajan Sriram, Raghavender Medishetti, Perumal Yogeeswari, Morla Shravan, Priyanka Suryadevara, Pushkar Kulkarni, Venkat Koushik Pulla, Jonnalagadda Padma Sridevi, Variam Ullas Jeankumar, Janupally Renuka
Publikováno v:
International Journal of Antimicrobial Agents. 43:269-278
DNA gyrase of Mycobacterium tuberculosis (MTB) is a type II topoisomerase that ensures the regulation of DNA topology and has been genetically demonstrated to be a bactericidal drug target. We present the discovery and optimisation of a novel series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f52bebc8c6ae4cfe978cf0bac3720c
https://doi.org/10.1016/j.ijantimicag.2013.12.006
https://doi.org/10.1016/j.ijantimicag.2013.12.006
Autor:
Renuka Janupally, Variam Ullas Jeankumar, Vijay Soni, Priyanka Suryadevara, Pushkar Kulkarni, Karyakulam Andrews Bobesh, Venkat Koushik Pulla, Parthiban Brindha Devi, Dharmarajan Sriram, Keerthana Sharma Chennubhotla, Perumal Yogeeswari
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:1661-1663
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::674a17d7ccf6b225f25014c47944d650
https://doi.org/10.1016/j.bmc.2015.02.024
https://doi.org/10.1016/j.bmc.2015.02.024
Autor:
Jonnalagadda Padma Sridevi, Perumal Yogeeswari, Dharmarajan Sriram, Priyanka Suryadevara, Brahmam Medapi, Janupally Renuka
Publikováno v:
European journal of medicinal chemistry. 103
Mycobacterial DNA gyrase B subunit has been identified to be one of the potentially underexploited drug targets in the field of antitubercular drug discovery. In the present study, we employed structural optimization of the reported GyrB inhibitor re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e15ec75f2d9eb8067f4f58cb74fe96
https://pubmed.ncbi.nlm.nih.gov/26318054
https://pubmed.ncbi.nlm.nih.gov/26318054
Autor:
Luiz Augusto Basso, Kenia Pissinate, Dharmarajan Sriram, Perumal Yogeeswari, Diógenes Santiago Santos, Diana C. Rostirolla, Pablo Machado, Priyanka Suryadevara, Laura Miranda Pinheiro
Publikováno v:
Journal of the Brazilian Chemical Society.
Using an orthologue-based design approach, we synthesized and assayed a series of thiazolyl-1H-benzo[d]imidazole derivatives as inhibitors of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase (MtIMPDH). From these experiments, a benzo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ced56f82defd7151807275420ee7765
https://doi.org/10.5935/0103-5053.20150104
https://doi.org/10.5935/0103-5053.20150104