Výsledky vyhledávání - "Priyanka Sonker"

Novel pyrimido-pyridazine derivatives: design, synthesis, anticancer evaluation and in silico studies

Autor: Priyanka Sonker, Mamata Singh, Manisha Nidhar, Vishal Prasad Sharma, Priyanka Yadav, Rashmi Singh, Biplob Koch, Ashish Kumar Tewari

Publikováno v: Future Medicinal Chemistry. 14:1693-1704

Aim: A novel pyrimido-pyridazine derivative for developing anticancer agents was synthesized via Ullmann arylation using an efficient Cu(OAc)2 catalyst. Materials & methods: Compounds were investigated for their anticancer potential, against human br

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f9dc867242b281654ff0e0ce1a2d8c2
https://doi.org/10.4155/fmc-2022-0199

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Lead modification via computational studies: Synthesis of pyrazole‐containing β‐amino carbonyls for the treatment of type 2 diabetes

Autor: Manisha Nidhar, Vipin Kumar, Archisman Mahapatra, Priya Gupta, Priyanka Yadav, Priyanka Sonker, Akhilesh Kumar, Shweta Mishra, Rahul Kumar Singh, Ashish Kumar Tewari

Publikováno v: Chemical Biology & Drug Design. 101:638-649

This article describes studies on the design, synthesis, and biological evaluation of pyrazole-containing β-amino carbonyl compounds (5a-5q) as DPP-4 inhibitors and anti-diabetic agents. In contrast, mannich reactions went smoothly with bismuth nitr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ed2bdf2f960659720866afe78ba008
https://doi.org/10.1111/cbdd.14157

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Design, synthesis and in-silico & in vitro enzymatic inhibition assays of pyrazole-chalcone derivatives as dual inhibitors of α-amylase & DPP-4 enzyme

Autor: Manisha Nidhar, Priyanka Sonker, Vishal Prasad Sharma, Sanjay Kumar, Ashish Kumar Tewari

Publikováno v: Chemical Papers. 76:1707-1720

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::42b3105c9137ce5cd9318af6b795c110
https://doi.org/10.1007/s11696-021-01985-1

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Iodine Catalyzed One Pot Synthesis of 4-Iodo-3-Phenylbenzo[B][ 1,6]Naphthyridine from Alkynylquinoline-3-Carbaldehydes, Via Imino Iodization of Alkynes

Autor: Rashmi Singh, Vishal Prasad Sharma, Priyanka Sonker, Priyanka Yadav, Radhey Mohan Singh, Ashish Kumar Tewari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c04db0f31196a7663ec60826ccf6018
https://doi.org/10.2139/ssrn.4388511

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Novel pyrimido-pyridazine derivatives: design, synthesis, anticancer evaluation and

Autor: Priyanka, Sonker, Mamata, Singh, Manisha, Nidhar, Vishal Prasad, Sharma, Priyanka, Yadav, Rashmi, Singh, Biplob, Koch, Ashish Kumar, Tewari

Publikováno v: Future medicinal chemistry.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4eb70c8505966eed7a624cf86a69c84e
https://pubmed.ncbi.nlm.nih.gov/36533662

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Sodium sulphide promoted synthesis of fused quinoline at room temperature

Autor: Vishal Prasad Sharma, Ashish Kumar Tewari, Radhey M. Singh, Rashmi Singh, Priyanka Sonker, Priyanka Yadav

Publikováno v: Organic & Biomolecular Chemistry. 19:8108-8112

A novel, simple and eco-friendly strategy for the synthesis of thiopyrano[4,3-b]quinolin-1-ones and pyrrolo[3,4-b]quinolin-1-ones from 2-alkynylquinoline-3-carbonitriles and sodium sulphide (Na2S·9H2O) under catalyst-free conditions at room temperat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de07741a75f18a53a439a1468c8f94a4
https://doi.org/10.1039/d1ob01085a

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Click inspired novel pyrazole-triazole-persulfonimidepyrazole-triazole-aryl derivatives; Design, synthesis, DPP-4 inhibitor with potential anti-diabetic agents

Autor: Manisha Nidhar, Shaziya Khanam, Priyanka Sonker, Priya Gupta, Archisman Mahapatra, Swaraj Patil, Brijesh Kumar Yadav, Rahul Kumar Singh, Ashish Kumar Tewari

Publikováno v: Bioorganic chemistry. 120

This work presented the first report on designing, synthesizing of novel pyrazole-triazole-persulfonimide (7a-i) and pyrazole-triazole-aryl derivatives (8a-j) via click reaction using CuI catalyst and evaluated for their anti-diabetic activity and DP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aeb158a2dc8db596cc60949d0d1503d
https://pubmed.ncbi.nlm.nih.gov/35051706

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Design, synthesis, and molecular modeling of heterodimer and inhibitors of α-amylase as hypoglycemic agents

Autor: Ved Prakash Singh, Manisha Nidhar, Pratima Yadav, Ranjeet Kumar, Priyanka Sonker, Ashish Kumar Tewari

Publikováno v: Molecular diversity.

A series of rosiglitazone-based heterodimers were designed and synthesized, and their α-amylase and antioxidant activity was evaluated. The binding mode of the compounds at the active site of PPARγ and α-amylase enzyme was explored using MolDock d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85554c02289a2e221c9511f9e10b18af
https://pubmed.ncbi.nlm.nih.gov/35357619

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Preparation, structure and dimerization of molecular tweezer: Cyanuric acid core based flexible symmetric linked pthalimide moiety as a heteroaromatic system

Autor: Priyanka Sonker, Ashish Kumar Tewari, Vishal Prasad Sharma, Archana Gaurav

Publikováno v: Journal of Molecular Structure. 1250:131743

Here, we synthesize tripodal tweezer molecule which have cyanuric acid in the center, propylene as a linker and pthalimide hetrocycle as terminal for conformational applications. The propylene linker promote intramolecular and intermolecular interact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f66ec1a1b54e4e787a6c9af4f58d881e
https://doi.org/10.1016/j.molstruc.2021.131743

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