Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Priyanka Somanath"'
Autor:
Nitasha D. Menon, Megha S. Kumar, T. G. Satheesh Babu, Sucharita Bose, Gayathri Vijayakumar, Manasi Baswe, Meghna Chatterjee, Jovita Rowena D’Silva, Kavya Shetty, Jayalekshmi Haripriyan, Anil Kumar, Samitha Nair, Priyanka Somanath, Bipin G. Nair, Victor Nizet, Geetha B. Kumar
Publikováno v:
mSphere, Vol 6, Iss 1 (2021)
In India, multidrug resistance determinants are much more abundant in community-associated bacterial pathogens due to the improper treatment of domestic and industrial effluents. In particular, a high bacterial load of the opportunistic pathogen P. a
Externí odkaz:
https://doaj.org/article/9537f523ff7445a3be0a708c8e548838
Publikováno v:
Stem Cell Research, Vol 31, Iss , Pp 83-94 (2018)
Developmental pluripotency associated factor 4 (Dppa4) is a highly specific marker of pluripotent cells, and is also overexpressed in certain cancers, but its function in either of these contexts is poorly understood. In this study, we use ChIP-Seq t
Externí odkaz:
https://doaj.org/article/d3313808350645479487f3abe97b0825
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185627 (2017)
The transcriptional functions of the class I histone deacetylases (HDACs) HDAC1 and HDAC2 are mainly viewed as both repressive and redundant based on murine knockout studies, but they may have additional independent roles and their physiological func
Externí odkaz:
https://doaj.org/article/76b1b4c7568b4b6a97753795f53c3580
851-P: Oral Long-Acting Menin Inhibitor Normalizes Type 2 Diabetes Mellitus (T2DM) in Two Rat Models
Publikováno v:
Diabetes. 71
Menin is a scaffold protein that has been recognized for its role in T2DM as a key regulator of β-cell proliferation. Menin inhibition has previously been shown to improve glycemic control in diabetic mice. Herein, we report the first evidence that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7891f53ad8ab3bda3c5af89b54f3042
https://doi.org/10.2337/db22-851-p
https://doi.org/10.2337/db22-851-p
Autor:
PRIYANKA SOMANATH, SANCHITA MOURYA, WEIQUN LI, TENLEY C. ARCHER, BRIAN LAW, DANIEL LU, TRIPTA RUGHWANI, LEKHA KUMAR, TAISEI KINOSHITA, MINI BALAKRISHNAN, THOMAS BUTLER
Publikováno v:
Diabetes. 71
Menin is an epigenetic regulatory protein that plays a key role in beta-cell proliferation and function, as previously demonstrated though increased beta-cell mass generation in Men1 knockout mice (Ja et al., 2021;13 (5) :e13524) . Here, we demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1be65788ade4db34efc1c9a068633d45
https://doi.org/10.2337/db22-113-lb
https://doi.org/10.2337/db22-113-lb
Publikováno v:
Cancer Research. 83:473-473
Chronic lymphocytic Leukemia (CLL) is the most common type of adult leukemia characterized by clonal proliferation of malignant B-lymphocytes. Although standard-of-care agents are well tolerated in CLL, patients with certain genetic subsets of the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdc68dae9926f04336b92ead84ec0d2e
https://doi.org/10.1158/1538-7445.am2023-473
https://doi.org/10.1158/1538-7445.am2023-473
Autor:
Brian Law, Tripta Rughwani, Tenley C. Archer, Lekha Kumar, Daniel Lu, Priyanka Somanath, Yan Ma, Xiaodong Wang, David Sperandio, Steve Morris, Thorsten Kirschberg, Mini Balakrishnan, Thomas Butler
Publikováno v:
Blood. 140:6191-6192
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5289e3a5d2cf691cf379d3acb110ca0
https://doi.org/10.1182/blood-2022-170445
https://doi.org/10.1182/blood-2022-170445
Autor:
Daniel Lu, Priyanka Somanath, Brian Law, Lekha Kumar, James Palmer, Taisei Kinoshita, Mini Balakrishnan, Thomas Butler
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S94
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa3a9bea8be5c1ab6952e03dcd673d46
https://doi.org/10.1016/s2152-2650(22)00437-2
https://doi.org/10.1016/s2152-2650(22)00437-2
Autor:
Priyanka Somanath, Daniel Lu, Brian Law, James T. Palmer, Taisei Kinoshita, Mini Balakrishnan, Thomas Butler
Publikováno v:
Cancer Research. 82:2654-2654
Double/Triple Hit Lymphoma (DHL/THL) and Double Expressor Lymphoma (DEL) are high-grade B-cell lymphomas (HGBCL) that exhibit low responses to standard therapeutic regimens resulting in poor prognosis. DHL harbor translocations in MYC and BCL2 or BCL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1df06c0fe094264fc035149a73c9f9bc
https://doi.org/10.1158/1538-7445.am2022-2654
https://doi.org/10.1158/1538-7445.am2022-2654
Publikováno v:
Cancer Research. 82:2665-2665
Introduction: KRAS (Kirsten rat sarcoma virus) is the most frequently mutated isoform amongst RAS oncogenes in human solid tumors being present in a high percentage of colorectal cancers (CRC), non-small cell lung cancers (NSCLC), and pancreatic canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb04bd63e2f28c41b390f32f3df3d05a
https://doi.org/10.1158/1538-7445.am2022-2665
https://doi.org/10.1158/1538-7445.am2022-2665