Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Priyanka Purkayastha"'
Resistance to multiple drugs is one of the significant barriers in the treatment of tuberculosis (TB). Knowledge of mechanisms of resistance is important to design effective treatment strategies. While mutations in genes coding for drug targets are t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79c44f9bcfbd8bf845058daf91327d6b
https://doi.org/10.1101/2022.12.18.519879
https://doi.org/10.1101/2022.12.18.519879
Publikováno v:
Molecular Informatics. 34:665-678
An atypical protein kinase C, PKMzeta has become an attractive target for various neurological disorders including long term potentiation, cognition, neuropathic pain and cancer. Drug discovery efforts have been hindered due to the non-availability o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ce75f3cbcdccc332cdd9d3548c97ec
https://doi.org/10.1002/minf.201500003
https://doi.org/10.1002/minf.201500003
Three-finger toxin (short and long neurotoxins) belongs to a super-family of non-enzymatic proteins found in all families of snakes. They have common three-dimensional structures of three beta-stranded loops extending from a central core containing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6ca39b4b3b9e9d2f2769ef97ff9542
Autor:
Srikar Varanasi, Perumal Yogeeswari, Priyanka Purkayastha, Dharmarajan Sriram, Aruna Malapathi
Publikováno v:
Advances in Intelligent Systems and Computing ISBN: 9788132227298
Kinase phosphorylates specific substrates by transferring phosphate from ATP. These are important targets for the treatment of various neurological disorders, drug addiction and cancer. To organize the kinases diversity and to compare distantly relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ddda0aa2ef0037bc6e203fcd7f41a75
https://doi.org/10.1007/978-81-322-2731-1_5
https://doi.org/10.1007/978-81-322-2731-1_5
Autor:
Aruna Malapati, Priyanka Purkayastha, Akhila Rallapalli, Perumal Yogeeswari, N. L. Bhanu Murthy, Dharmarajan Sriram
Publikováno v:
Computational Intelligence in Medical Informatics ISBN: 9789812872593
Classification of kinases will provide comparison of related human kinases and insights into kinases functions and evolution. Several algorithms exist for classification and most of them failed to classify when the dimension of feature set large. Sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03a1c454c438c19afe95f96e8c885ae9
https://doi.org/10.1007/978-981-287-260-9_8
https://doi.org/10.1007/978-981-287-260-9_8
Publikováno v:
Current medicinal chemistry. 22(15)
Balance between excitatory glutamate and inhibitory GABA neurotransmitter is essential and critical for proper development and functioning of brain. GABAergic (gamma aminobutyric acid) and glutamatergic interneurons maintain excitability, integrity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86887d76fbe9b9276553260c3109240e
https://pubmed.ncbi.nlm.nih.gov/25666800
https://pubmed.ncbi.nlm.nih.gov/25666800