Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Priyanka Madireddi"'
Autor:
Jean-Pierre J. Issa, Donald L. Gill, Stephen B. Baylin, Ying Cui, Jaroslav Jelinek, Andrew J. Andrews, Ryan A. Henry, Magid Abou-Gharbia, Wayne E. Childers, Woonbok Chung, Saira Ahmed, Vazganush Gharibyan, Elisha J. Dettman, Sarah Dumont, Gabriel G. Malouf, Judith Garriga, Priyanka Madireddi, Annie Beaudry, Youjun Wang, Justin T. Lee, Noël J.-M. Raynal
Table S2. Drug screening results after treatment at 50 µM for 24h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e20fe297d747c2ae370fcf3f0554856
https://doi.org/10.1158/0008-5472.22410422.v1
https://doi.org/10.1158/0008-5472.22410422.v1
Autor:
Jean-Pierre J. Issa, Donald L. Gill, Stephen B. Baylin, Ying Cui, Jaroslav Jelinek, Andrew J. Andrews, Ryan A. Henry, Magid Abou-Gharbia, Wayne E. Childers, Woonbok Chung, Saira Ahmed, Vazganush Gharibyan, Elisha J. Dettman, Sarah Dumont, Gabriel G. Malouf, Judith Garriga, Priyanka Madireddi, Annie Beaudry, Youjun Wang, Justin T. Lee, Noël J.-M. Raynal
Table S1. Drug screening results after treatment at 10 µM for 72h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ab28b8016b839f6638ea48212d6766
https://doi.org/10.1158/0008-5472.22410425.v1
https://doi.org/10.1158/0008-5472.22410425.v1
Autor:
Jean-Pierre J. Issa, Donald L. Gill, Stephen B. Baylin, Ying Cui, Jaroslav Jelinek, Andrew J. Andrews, Ryan A. Henry, Magid Abou-Gharbia, Wayne E. Childers, Woonbok Chung, Saira Ahmed, Vazganush Gharibyan, Elisha J. Dettman, Sarah Dumont, Gabriel G. Malouf, Judith Garriga, Priyanka Madireddi, Annie Beaudry, Youjun Wang, Justin T. Lee, Noël J.-M. Raynal
Targeting epigenetic pathways is a promising approach for cancer therapy. Here, we report on the unexpected finding that targeting calcium signaling can reverse epigenetic silencing of tumor suppressor genes (TSG). In a screen for drugs that reactiva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0f817e19e755cef513de38bde1007a
https://doi.org/10.1158/0008-5472.c.6507992
https://doi.org/10.1158/0008-5472.c.6507992
Autor:
Jean-Pierre J. Issa, Donald L. Gill, Stephen B. Baylin, Ying Cui, Jaroslav Jelinek, Andrew J. Andrews, Ryan A. Henry, Magid Abou-Gharbia, Wayne E. Childers, Woonbok Chung, Saira Ahmed, Vazganush Gharibyan, Elisha J. Dettman, Sarah Dumont, Gabriel G. Malouf, Judith Garriga, Priyanka Madireddi, Annie Beaudry, Youjun Wang, Justin T. Lee, Noël J.-M. Raynal
Supplementary Materials and Methods and Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f02f937c2b2831a03d2e683780dc77d
https://doi.org/10.1158/0008-5472.22410434.v1
https://doi.org/10.1158/0008-5472.22410434.v1
Autor:
Jean-Pierre J. Issa, Donald L. Gill, Stephen B. Baylin, Ying Cui, Jaroslav Jelinek, Andrew J. Andrews, Ryan A. Henry, Magid Abou-Gharbia, Wayne E. Childers, Woonbok Chung, Saira Ahmed, Vazganush Gharibyan, Elisha J. Dettman, Sarah Dumont, Gabriel G. Malouf, Judith Garriga, Priyanka Madireddi, Annie Beaudry, Youjun Wang, Justin T. Lee, Noël J.-M. Raynal
Supplementary Figure S1. Drug screening based on the measurement of GFP fluorescence by flow cytometry. Supplementary Figure S2. Dose response curves of GFP reactivation after cardiac glycosides treatment. Supplementary Figure S3. Tumor suppressor ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e9062d4853e469ccfe0d9e8a1fd3350
https://doi.org/10.1158/0008-5472.22410428
https://doi.org/10.1158/0008-5472.22410428
Autor:
Charly R. Good, Andrew Kelly, Jozef Madzo, Jean Pierre J. Issa, Patricia Kropf, Priyanka Madireddi, Jaroslav Jelinek
Publikováno v:
Leukemia
Acute myeloid leukemia (AML) often harbors mutations in epigenetic regulators, and also has frequent DNA hypermethylation, including the presence of CpG island methylator phenotypes (CIMPs). Although global hypomethylation is well known in cancer, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e406302f22dd4376a5c76741af9c5a4b
https://doi.org/10.1038/s41375-018-0084-2
https://doi.org/10.1038/s41375-018-0084-2
Autor:
Priyanka Madireddi, Silvia Maifrede, Andrew Magimaidas, Dan A. Liebermann, Barbara Hoffman, Kaushiki Mukherjee
Publikováno v:
Oncotarget
The GADD45 family of proteins functions as stress sensors in response to various physiological and environmental stressors. Here we show that primary mouse embryo fibroblasts (MEFs) from Gadd45b null mice proliferate slowly, accumulate increased leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff803ebc071375a9433873cb63aa7bfd
https://doi.org/10.18632/oncotarget.8854
https://doi.org/10.18632/oncotarget.8854
Publikováno v:
Stem cell investigation. 3
Mammalian Sirtuin protein family consists of SIRT1-SIRT7. Sirtuins are NAD+-dependent histone deacetylases (HDACs) known to regulate metabolic homeostasis, chromatin structure and DNA repair thereby regulating genomic stability. They were first disco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73335f72b3380ba90f7204f04cc83acb
https://pubmed.ncbi.nlm.nih.gov/27058938
https://pubmed.ncbi.nlm.nih.gov/27058938
Autor:
Annie Beaudry, Wayne E. Childers, Woonbok Chung, Judith Garriga, Saira Ahmed, Stephen B. Baylin, Youjun Wang, Priyanka Madireddi, Andrew J. Andrews, Justin T. Lee, Gabriel G. Malouf, Elisha J. Dettman, Donald L. Gill, Magid Abou-Gharbia, Ying Cui, Jean Pierre J. Issa, Vazganush Gharibyan, Noël J.-M. Raynal, Ryan A. Henry, Sarah N. Dumont, Jaroslav Jelinek
Targeting epigenetic pathways is a promising approach for cancer therapy. Here, we report on the unexpected finding that targeting calcium signaling can reverse epigenetic silencing of tumor suppressor genes (TSG). In a screen for drugs that reactiva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e6a5a034aa2a49ddaf2707d9d5b826
https://europepmc.org/articles/PMC4794357/
https://europepmc.org/articles/PMC4794357/
Autor:
Karthik Mallilankaraman, J. Kevin Foskett, Krishna M. Irrinki, György Hajnóczky, Muniswamy Madesh, Jordi Molgó, Tünde Golenár, Harish C. Chandramoorthy, Patrick J. Doonan, Russell A. Miller, Brett A. Kaufman, Jun Yang, Jill E. Kolesar, Marioly Müller, György Csordás, Priyanka Madireddi, César Cárdenas
Publikováno v:
Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2015, 17 (7), pp.953. ⟨10.1038/ncb3202⟩
Nature Cell Biology, Nature Publishing Group, 2015, 17 (7), pp.953. ⟨10.1038/ncb3202⟩
Ca(2+) flux across the mitochondrial inner membrane regulates bioenergetics, cytoplasmic Ca(2+) signals and activation of cell death pathways. Mitochondrial Ca(2+) uptake occurs at regions of close apposition with intracellular Ca(2+) release sites,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88ba6c10026f546fb4d974ae58d4704
https://hal.archives-ouvertes.fr/hal-01178820
https://hal.archives-ouvertes.fr/hal-01178820