Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Priyanka Gokulnath"'
Publikováno v:
Genes and Diseases, Vol 11, Iss 5, Pp 101045- (2024)
RNA N6-methyladenosine (m6A) methylation is the most abundant and conserved RNA modification in eukaryotes. It participates in the regulation of RNA metabolism and various pathophysiological processes. Non-coding RNAs (ncRNAs) are defined as small or
Externí odkaz:
https://doaj.org/article/74fa9cb5139342228741cd28f3d12e05
Publikováno v:
Sports Medicine - Open, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract Exercise has well-recognized beneficial effects on the whole body. Previous studies suggest that exercise could promote tissue regeneration and repair in various organs. In this review, we have summarized the major effects of exercise on tis
Externí odkaz:
https://doaj.org/article/4da35b87e84e46f2b2a94e602f1ac1b8
Autor:
Qi Liu, Weilin Yuan, Yuwei Yan, Bing Jin, Mengke You, Tianqi Liu, Mingchun Gao, Jin Li, Priyanka Gokulnath, Gururaja Vulugundam, Guoping Li, Bin Xu, Junjie Xiao
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 527-540 (2023)
Muscle atrophy is debilitating and can be induced by several stressors. Unfortunately, there are no effective pharmacological treatment until now. MicroRNA (miR)-29b is an important target that we identified to be commonly involved in multiple types
Externí odkaz:
https://doaj.org/article/a39ffc5d6fae4664a83b62f8080937ce
Autor:
Spyros A. Papiris, Lykourgos Kolilekas, Natalia Rivera, Michail Spanos, Guoping Li, Priyanka Gokulnath, Emeli Chatterjee, Alexandros Georgakopoulos, Maria Kallieri, Andriana I. Papaioannou, Thomas Raptakis, Vasiliki Apollonatou, Elvira-Markela Antonogiannaki, Elias Gialafos, Sofia Chatziioannou, Johan Grunewald, Effrosyni D. Manali
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Sarcoidosis is an inflammatory granulomatous disease of unknown etiology involving any organ or tissue along with any combination of active sites, even the most silent ones clinically. The unpredictable nature of the sites involved in sarcoidosis dic
Externí odkaz:
https://doaj.org/article/57adaa43b8a24d66be8353571ce9e89c
Delivery of engineered extracellular vesicles with miR-29b editing system for muscle atrophy therapy
Autor:
Rui Chen, Weilin Yuan, Yongjun Zheng, Xiaolan Zhu, Bing Jin, Tingting Yang, Yuwei Yan, Wanru Xu, Hongjian Chen, Juan Gao, Guoping Li, Priyanka Gokulnath, Gururaja Vulugundam, Jin Li, Junjie Xiao
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Muscle atrophy is a frequently observed complication, characterized by the loss of muscle mass and strength, which diminishes the quality of life and survival. No effective therapy except exercise is currently available. In our previous stud
Externí odkaz:
https://doaj.org/article/91fac70d2c9b4158a31794fac49526ff
Autor:
Juan Gao, Jiaxin Song, Yuwei Yan, Priyanka Gokulnath, Gururaja Vulugundam, Guoping Li, Qingyi Zhan, Fei Jiang, Yanjuan Lin, Junjie Xiao
Publikováno v:
Reviews in Cardiovascular Medicine, Vol 24, Iss 9, p 251 (2023)
Exercise training (ET) is an important non-drug adjuvant therapy against many human diseases, including cardiovascular diseases. The appropriate ET intensity induces beneficial adaptions and improves physiological function and cardiopulmonary fitness
Externí odkaz:
https://doaj.org/article/813d46dd9697419587bb239b0257cbdd
Autor:
Michail Spanos, Sigal Shachar, Thadryan Sweeney, H. Immo Lehmann, Priyanka Gokulnath, Guoping Li, George B. Sigal, Rajini Nagaraj, Pradeepthi Bathala, Farhan Rana, Ravi V. Shah, David A. Routenberg, Saumya Das
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104833- (2022)
Summary: Patients with SARS-CoV-2 infection (COVID-19) risk developing long-term neurologic symptoms after infection. Here, we identify biomarkers associated with neurologic sequelae one year after hospitalization for SARS-CoV-2 infection. SARS-CoV-2
Externí odkaz:
https://doaj.org/article/038a4058d8e64404a52471da81c08966
Relevance of Ferroptosis to Cardiotoxicity Caused by Anthracyclines: Mechanisms to Target Treatments
Autor:
Guoxia Zhang, Chao Yuan, Xin Su, Jianzhen Zhang, Priyanka Gokulnath, Gururaja Vulugundam, Guoping Li, Xinyu Yang, Na An, Can Liu, Wanli Sun, Hengwen Chen, Min Wu, Shipeng Sun, Yanwei Xing
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Anthracyclines (ANTs) are a class of anticancer drugs widely used in oncology. However, the clinical application of ANTs is limited by their cardiotoxicity. The mechanisms underlying ANTs-induced cardiotoxicity (AIC) are complicated and involve oxida
Externí odkaz:
https://doaj.org/article/c4be74bc9d47432782d6426e2892d157
Autor:
Guoping Li, Aidan C. Manning, Alex Bagi, Xinyu Yang, Priyanka Gokulnath, Michail Spanos, Jonathan Howard, Patricia P. Chan, Thadryan Sweeney, Robert Kitchen, Haobo Li, Brice D. Laurent, Sary F. Aranki, Maria I. Kontaridis, Louise C. Laurent, Kendall Van Keuren‐Jensen, Jochen Muehlschlegel, Todd M. Lowe, Saumya Das
Publikováno v:
Advanced Science, Vol 9, Iss 17, Pp n/a-n/a (2022)
Abstract The cellular response to stress is an important determinant of disease pathogenesis. Uncovering the molecular fingerprints of distinct stress responses may identify novel biomarkers and key signaling pathways for different diseases. Emerging
Externí odkaz:
https://doaj.org/article/1c604b8983c147c197c8d6c4daa9b57a
Publikováno v:
EBioMedicine, Vol 76, Iss , Pp 103813- (2022)
Summary: Human pluripotent stem cell (hPSC) technology has offered nearly infinite opportunities to model all kinds of human diseases in vitro. Cardiomyocytes derived from hPSCs have proved to be efficient tools for cardiac disease modeling, drug scr
Externí odkaz:
https://doaj.org/article/cf52124ee19b4207970bf1125c53b00e