Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Priyangi A. Malaviarachchi"'
Autor:
Roger D. Pechous, Priyangi A. Malaviarachchi, Zhuo Xing, Avrium Douglas, Samantha D. Crane, Hayley M. Theriot, Zijing Zhang, Alireza Ghaffarieh, Lu Huang, Y. Eugene Yu, Xuming Zhang
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 543 (2024)
Recent epidemiological studies suggest that individuals with Down syndrome are more susceptible to SARS-CoV-2 infection and have higher rates of hospitalization and mortality than the general population. However, the main drivers behind these dispara
Externí odkaz:
https://doaj.org/article/5e629ecf568c44d89c6c8f79af9ad60d
Autor:
Roger D. Pechous, Priyangi A. Malaviarachchi, Srijon K. Banerjee, Stephanie D. Byrum, Duah H. Alkam, Alireza Ghaffarieh, Richard C. Kurten, Joshua L. Kennedy, Xuming Zhang
Publikováno v:
bioRxiv
COVID-19 has claimed millions of lives since the emergence of SARS-CoV-2, and lung disease appears the primary cause of the death in COVID-19 patients. However, the underlying mechanisms of COVID-19 pathogenesis remain elusive, and there is no existi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb8566650ec76f0792d8376ffd55468
https://europepmc.org/articles/PMC10153187/
https://europepmc.org/articles/PMC10153187/
Publikováno v:
Infect Immun
CD4 T cell-dependent IFNγ production and antibody are the two best known effectors for protective immunity against Chlamydia female reproductive tract (FRT) infection. Nevertheless, mice lacking either IFNγ or B cells can clear the vast majority of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce3907a83c44f16236baba58077f3d8
https://doi.org/10.1128/iai.00328-22
https://doi.org/10.1128/iai.00328-22
CD4 T cell-dependent IFNγ production and antibody are the two best known effectors for protective immunity againstChlamydiafemale reproductive tract (FRT) infection. Nevertheless, mice lacking either IFNγ or B cells are capable of clearing vast maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19ea7606089e2a2722bc119d63eba1a5
https://doi.org/10.1101/2022.08.04.502902
https://doi.org/10.1101/2022.08.04.502902
Protective immunity to the obligate intracellular bacterium Chlamydia is thought to rely on CD4 T cell-dependent IFNγ production. Nevertheless, whether IFNγ is produced by other cellular source during Chlamydia infection and how CD4 T cell-dependen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4692edde227f9f437077575c186eac93
https://doi.org/10.1101/2020.08.26.269480
https://doi.org/10.1101/2020.08.26.269480
Publikováno v:
Eur J Immunol
The obligate intracellular bacterium Chlamydia trachomatis causes the most prevalent bacterial sexually transmitted infection worldwide. CD4 T cells play a central role in the protective immunity against Chlamydia female reproductive tract (FRT) infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29117788a250d21c91844ed89a82a0d2
https://pubmed.ncbi.nlm.nih.gov/32026472
https://pubmed.ncbi.nlm.nih.gov/32026472
Autor:
Jingliao Zhang, Yan Yan, Nicholas J. Baltz, Peter D. Emanuel, Y. Lucy Liu, Priyangi A. Malaviarachchi, Zhifu Xiang
Publikováno v:
Cellular signalling. 50
Constitutively activated MAPK and AKT signaling pathways are often found in solid tumors and leukemias. PTEN is one of the tumor suppressors that are frequently found deficient in patients with late-stage cancers or leukemias. In this study we demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faab8c17074b42fe9fb3efc4809e9848
https://pubmed.ncbi.nlm.nih.gov/29964149
https://pubmed.ncbi.nlm.nih.gov/29964149
Publikováno v:
Human Genetics
PTEN is one of the most frequently mutated tumor suppressor genes in human cancers. Mutations occur in either heritable or sporadic fashion. Sequencing of cDNA from patients and normal individuals often reveals splicing variants (SVs) of PTEN, some o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d7e81ade54a3c2943bee58e0fb24fd9
https://doi.org/10.1007/s00439-010-0886-4
https://doi.org/10.1007/s00439-010-0886-4
Autor:
Jumei Shi, Priyangi A. Malaviarachchi, John D. Shaughnessy, Brian Storrie, Arend Mulder, Bart Barlogie, Tarun K. Garg, Frits van Rhee, Susann Szmania, Rachel E. Kellum, Guido Tricot
Publikováno v:
Blood. 111:1309-1317
Human leukocyte antigen class I molecules expressed by tumor cells play a central role in the regulation of natural killer (NK) cell–mediated immune responses. The proteasome inhibitor bortezomib has demonstrated significant activity in multiple my
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfc1ae0ebcd9f95271a7719d6b8f106
https://doi.org/10.1182/blood-2007-03-078535
https://doi.org/10.1182/blood-2007-03-078535