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pro vyhledávání: '"Priyanga Appasamy"'
Autor:
Jeetendra Kumar Nag, Sorina Grisaru-Granovsky, Shunit Armon, Tatyana Rudina, Priyanga Appasamy, Rachel Bar-Shavit
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 246 (2024)
Studying primordial events in cancer is pivotal for identifying predictive molecular indicators and for targeted intervention. While the involvement of G-protein-coupled receptors (GPCRs) in cancer is growing, GPCR-based therapies are yet rare. Here,
Externí odkaz:
https://doaj.org/article/24158ce71a4e4b71883c28206189c095
Autor:
Jeetendra Kumar Nag, Hodaya Malka, Shoshana Sedley, Priyanga Appasamy, Tatyana Rudina, Tgst Levi, Amnon Hoffman, Chaim Gilon, Beatrice Uziely, Rachel Bar-Shavit
Publikováno v:
Molecular Cancer Therapeutics. 21:1415-1429
While the role of G-protein–coupled receptors (GPCR) in cancer is acknowledged, their underlying signaling pathways are understudied. Protease-activated receptors (PAR), a subgroup of GPCRs, form a family of four members (PAR1–4) centrally involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3fcaa5744d55ebaea04c3a61fe4302a
https://doi.org/10.1158/1535-7163.mct-21-0946
https://doi.org/10.1158/1535-7163.mct-21-0946
Supplementary Figure from PH-Binding Motif in PAR4 Oncogene: From Molecular Mechanism to Drug Design
Autor:
Rachel Bar-Shavit, Beatrice Uziely, Chaim Gilon, Amnon Hoffman, Tgst Levi, Tatyana Rudina, Priyanga Appasamy, Shoshana Sedley, Hodaya Malka, Jeetendra Kumar Nag
Supplementary Figure from PH-Binding Motif in PAR4 Oncogene: From Molecular Mechanism to Drug Design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0453d20132cce1787e1084d5606b5234
https://doi.org/10.1158/1535-7163.22523497
https://doi.org/10.1158/1535-7163.22523497
Autor:
Rachel Bar-Shavit, Beatrice Uziely, Chaim Gilon, Amnon Hoffman, Tgst Levi, Tatyana Rudina, Priyanga Appasamy, Shoshana Sedley, Hodaya Malka, Jeetendra Kumar Nag
Supplementary Table from PH-Binding Motif in PAR4 Oncogene: From Molecular Mechanism to Drug Design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a76f2d36747c9732a6e06237440834b
https://doi.org/10.1158/1535-7163.22523494
https://doi.org/10.1158/1535-7163.22523494
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8985, p 8985 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The essential role of G-protein coupled receptors (GPCRs) in tumor growth is recognized, yet a GPCR based drug in cancer is rare. Understanding the molecular path of a tumor driver gene may lead to the design and development of an effective drug. For
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4869a170a857e8db3d42175341e3fe
https://www.mdpi.com/1422-0067/22/16/8985
https://www.mdpi.com/1422-0067/22/16/8985
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