Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Priya Venkatakrishnan"'
Autor:
Linda J. Roman, Madeline G. Roman, Srikanth R. Polusani, Bettie Sue Siler Masters, Priya Venkatakrishnan, Satya Prakash Panda, Borries Demeler, Dean L. Kellogg
Publikováno v:
Archives of Biochemistry and Biophysics. 533:88-94
Nitric oxide synthases (NOSs) synthesize nitric oxide (NO), a signaling molecule, from l-arginine, utilizing electrons from NADPH. NOSs are flavo-hemo proteins, with two flavin molecules (FAD and FMN) and one heme per monomer, which require the bindi
Publikováno v:
Journal of Biological Chemistry. 284:19843-19855
Data, both for and against the presence of a mitochondrial nitric-oxide synthase (NOS) isoform, is in the refereed literature. However, irrefutable evidence has not been forthcoming. In light of this controversy, we designed studies to investigate th
Proteomic characterization of lipid raft proteins in amyotrophic lateral sclerosis mouse spinal cord
Autor:
Renee Kilty, Anna-Lena Ström, Haining Zhu, Eric J. Smart, Jianjun Zhai, William V. Everson, Priya Venkatakrishnan, James White
Publikováno v:
FEBS Journal. 276:3308-3323
Familial amyotrophic lateral sclerosis (ALS) has been linked to mutations in the copper/zinc superoxide dismutase (SOD1) gene. The mutant SOD1 protein exhibits a toxic gain-of-function that adversely affects the function of neurons. However, the mech
Publikováno v:
Phytotherapy Research. 23:1663-1672
Studies were conducted with extracts of several varieties of tobacco in search of neuronal nitric oxide synthase (nNOS) inhibitors which may be of value in the treatment of stroke. Current therapies do not directly exploit modulation of nNOS activity
Autor:
Linda J. Roman, Changjian Feng, Li Chen, Andrei V. Astashkin, Satya Prakash Panda, Bettie Sue Siler Masters, Wenbing Li, Priya Venkatakrishnan
Neuronal nitric oxide synthase μ (nNOSμ) contains 34 additional residues in an autoregulatory element compared to nNOSα. Cytochrome c and flavin reductions in the absence of calmodulin (CaM) were faster in nNOSμ than nNOSα, while rates in the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8c3278c702bc637c42b62e77e2d7d1
https://europepmc.org/articles/PMC3897158/
https://europepmc.org/articles/PMC3897158/
Autor:
Linda J. Roman, Martin L. Adamo, Neha Garg, Bettie Sue Siler Masters, Madeline G. Roman, Kathryn Hinchee-Rodriguez, Priya Venkatakrishnan
Publikováno v:
Biochemical and biophysical research communications. 435(3)
Type 2 Diabetes (T2DM) is the seventh leading cause of death in the United States, and is quickly becoming a global pandemic. T2DM results from reduced insulin sensitivity coupled with a relative failure of insulin secretion. Reduced insulin sensitiv
A muscle‐specific isoform of neuronal nitric oxide synthase is phosphorylated in response to insulin
Autor:
Priya Venkatakrishnan, Neha Garg, Bettie Sue Siler Masters, Kathryn Hinchee-Rodriguez, Martin L. Adamo, Linda J. Roman, Madeline G. Roman
Publikováno v:
The FASEB Journal. 27
Publikováno v:
The FASEB Journal. 26
Publikováno v:
The FASEB Journal. 24
Publikováno v:
Biochemical and biophysical research communications. 394(3)
Previously, in tightly controlled studies, using three independent, yet complementary techniques, we refuted the claim that a mitochondrial nitric oxide synthase (mtNOS) isoform exists within pure, rat liver mitochondria (MT). Of those techniques, th