Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Priya S. Chockalingam"'
Autor:
Guodong Zhang, Michael Cwik, Jonathan A. Bernstein, Yongquan Lai, Priya S. Chockalingam, Neil Inhaber, Jiang Wu, Zhiwei Zhou
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 195
Hereditary angioedema (HAE) is a rare genetic disease caused by deficiency or dysfunction of C1 esterase inhibitor (C1-INH). Plasma C1-INH activity and concentrations of C1-INH and complement components 1q and 4 (C1q, C4) are critical to the HAE diag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd64204b1f710cbabeb4964d7b8caa19
https://pubmed.ncbi.nlm.nih.gov/33388640
https://pubmed.ncbi.nlm.nih.gov/33388640
Autor:
Priya S. Chockalingam, Neil Inhaber, Jonathan A. Bernstein, Yongquan Lai, Jiang Wu, Guodong Zhang, Zhiwei Zhou
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 504
Background Hereditary angioedema (HAE) is a rare genetic disease caused by deficiency or dysfunction of C1 esterase inhibitor (C1-INH). Timely and accurate diagnosis is an ongoing challenge. Measurement of plasma C1-INH activity is currently the crit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb10e8af7341452401b77ebcdc1630a
https://pubmed.ncbi.nlm.nih.gov/32059947
https://pubmed.ncbi.nlm.nih.gov/32059947
Autor:
Priya S. Chockalingam, Stephen Fait, Hans Boehringer, Zhiwei Zhou, Roy B. Chung, Brijesh K. Garg
Publikováno v:
International Immunopharmacology. 83:106526
Hereditary Angioedema (HAE) is a rare, autosomal dominant disease caused by mutations in SERPING1 gene leading to dysfunction/deficiency of C1-esterase inhibitor (C1-INH) protein and subsequent dysregulation of the contact system and bradykinin overp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98b00b5b8e0b186bab2edc497445e3e3
https://doi.org/10.1016/j.intimp.2020.106526
https://doi.org/10.1016/j.intimp.2020.106526
Publikováno v:
International Immunopharmacology. 81:106348
Hereditary angioedema (HAE) types I and II are characterized by functional C1 inhibitor (fC1-INH) deficiency which results in bradykinin overproduction. Sensitive, specific and robust methods to quantitate fC1-INH in human samples are required for di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43735d303f976bcd357c4964c4421053
https://doi.org/10.1016/j.intimp.2020.106348
https://doi.org/10.1016/j.intimp.2020.106348
Autor:
Shawn P. O'Neil, Gabriela Campanholle, Eva E. Nagiec, Bruce L. Homer, Lih-Ling Lin, Hendrik Neubert, Karrie A. Brenneman, Ju Wang, Margaret Fleming, Steven Evans, Riyez Karim, Yutian Zhan, Priya S. Chockalingam, Nicholas Pullen, M Nusrat Sharif, Jameel Syed
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155368 (2016)
PLoS ONE
PLoS ONE
The cytokine TWEAK and its cognate receptor Fn14 are members of the TNF/TNFR superfamily and are upregulated in tissue injury to mediate local tissue responses including inflammation and tissue remodeling. We found that in various models of kidney di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c93f29ba883c9222ec9827c569a3677d
http://europepmc.org/articles/PMC4865213?pdf=render
http://europepmc.org/articles/PMC4865213?pdf=render
Autor:
Yonghan Hu, Jennifer R. Thomason, Steve Tam, Priya S. Chockalingam, Erica Reifenberg, Manus Ipek, Jason Shaoyun Xiang, Huan-Qiu Li, Richard Sheldon, Li Xing, Elisabeth A. Morris, Joshua James Sabatini, Katy E. Georgiadis, Satenig Guler
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:6800-6803
Design, synthesis and structure–activity relationship of a series of biphenylsulfonamido-3-methylbutanoic acid based aggrecanase-1 inhibitors are described. In addition to robust aggrecanase-1 inhibition, these compounds also exhibit potent MMP-13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f06996759f6d930ba801380ed1352ce5
https://doi.org/10.1016/j.bmcl.2011.09.036
https://doi.org/10.1016/j.bmcl.2011.09.036
Autor:
Mary Kay Harper, Gina C. Mangalindan, Tim S. Bugni, Min He, Emily L. Whitson, Gisela P. Concepcion, Frank V. Ritacco, John N. A. Hooper, Priya S. Chockalingam, Chris M. Ireland
Publikováno v:
Journal of Natural Products
Three new sterol sulfates, spheciosterol sulfates A-C (1-3), and the known sterol sulfate topsentiasterol sulfate E (4) have been isolated from the sponge Spheciospongia sp., collected in the Philippines. Structures were assigned on the basis of exte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397a72daefbf3d909e451d4bc38203d2
http://europepmc.org/articles/PMC2593898
http://europepmc.org/articles/PMC2593898
Autor:
S.S. Glasson, Richard Sheldon, Tracey Blanchet, Manas K. Majumdar, Priya S. Chockalingam, Elisabeth A. Morris, Cristin C. Keohan, Ramesh A. Bhat
Publikováno v:
Journal of Cellular Physiology. 215:68-76
Articular cartilage chondrocytes help in the maintenance of tissue homeostasis and function of the articular joint. Study of primary chondrocytes in culture provides information closely related to in vivo functions of these cells. Limitations in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7007698f12001f4cc7058e4e7d8f3b23
https://doi.org/10.1002/jcp.21282
https://doi.org/10.1002/jcp.21282
Autor:
Paul J. Yaworsky, Richard Sheldon, Usha Varadarajan, Eric Fortier, Manas K. Majumdar, Edward R. Lavallie, Priya S. Chockalingam, Elisabeth A. Morris
Publikováno v:
Arthritis & Rheumatism. 56:4074-4083
Objective Protein kinase Czeta (PKCzeta), an atypical PKC, has been found to be transcriptionally up-regulated in human osteoarthritic (OA) articular cartilage. This study was undertaken to examine the role of PKCzeta in interleukin-1beta (IL-1beta)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009e53ab42277b61fabc04cf13164fb7
https://doi.org/10.1002/art.23043
https://doi.org/10.1002/art.23043
Autor:
Tracey Blanchet, Elisabeth A. Morris, Richard Sheldon, Priya S. Chockalingam, S.S. Glasson, Manas K. Majumdar, Ramesh A. Bhat, Cristin C. Keohan
Publikováno v:
Journal of Cellular Physiology. 209:551-559
Chondrocytes are unique to cartilage and the study of these cells in vitro is important for advancing our understanding of the role of these cells in normal homeostasis and disease including osteoarthritis (OA). As there are limitations to the cultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e59256e5a8a90493f8476c0ae5c3d5
https://doi.org/10.1002/jcp.20775
https://doi.org/10.1002/jcp.20775