Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Priya Dondapati"'
Autor:
Thiagarajan Venkatesan, Ali Alaseem, Aiyavu Chinnaiyan, Sivanesan Dhandayuthapani, Thanigaivelan Kanagasabai, Khalid Alhazzani, Priya Dondapati, Saad Alobid, Umamaheswari Natarajan, Ruben Schwartz, Appu Rathinavelu
Publikováno v:
Cells, Vol 7, Iss 5, p 41 (2018)
The Murine Double Minute 2 (MDM2) amplification or overexpression has been found in many tumors with high metastatic and angiogenic ability. Our experiments were designed to explore the impact of MDM2 overexpression, specifically on the levels of ang
Externí odkaz:
https://doaj.org/article/b32d1e9cf99540b493245b2f3bda1b17
Autor:
Rashmi Pathak, Macall Leslie, Priya Dondapati, Rachel Davis, Kenichi Tanaka, Elizabeth Jett, Inna Chervoneva, Takemi Tanaka
Publikováno v:
Breast Cancer.
Background Substantial evidence indicates that delay of first treatment after diagnosis is associated with poorer survival outcomes in breast cancer. Accordingly, the Commission on Cancer introduced a quality measure for receipt of therapeutic surger
Autor:
Cruz McCarty, Misung Yi, Senna Sous, Macall Leslie, Ezza Tariq, Priya Dondapati, Hiroyasu Kameyama, Shreya Nuguri, Natalie Hills, Marielle Wilkerson, Rachel Davis, Sidra Mesiya, Hallgeir Rui, Inna Chervoneva, Roy Zhang, Takemi Tanaka
Publikováno v:
Pathobiology : journal of immunopathology, molecular and cellular biology.
Introduction: Needle biopsy is essential for definitive diagnosis of breast malignancy. Significant histologic changes due to tissue damage have been reported in solid tumors. This study investigated the association between time from needle biopsy an
Autor:
Ali Alaseem, Arkene Levy, Saad Alobid, Keerthi Thallapureddy, Appu Rathinavelu, Priya Dondapati, Khalid Alhazzani, Paramajot Kaur, Khadijah Cheema
Publikováno v:
Current Cancer Drug Targets. 19:179-188
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase, which is an essential player in regulating cell migration, invasion, adhesion, proliferation, and survival. Its overexpression and activation have been identified in sixty-eight percent o
Autor:
Appu Rathinavelu, Ali Alaseem, Anupam Bishayee, Saad Alobid, Priya Dondapati, Khalid Alhazzani
Publikováno v:
Seminars in cancer biology. 56
Matrix metalloproteinases (MMPs) are members of zinc-dependent endopeptidases implicated in a variety of physiological and pathological processes. Over the decades, MMPs have been studied for their role in cancer progression, migration, and metastasi
Publikováno v:
Cancer Research. 79:1887-1887
Epithelial-Mesenchymal Transition (EMT) is a key step in the induction of metastasis, which is critical for the conversion of early-stage prostate tumors into metastatic malignancies. Therefore, identifying the signaling pathways promoting EMT is cru
Autor:
Thanigaivelan Kanagasabai, Appu Rathinavelu, Umamaheswari Natarajan, Khalid Alhazzani, Aiyavu Chinnaiyan, Priya Dondapati, Ali Alaseem, Thiagarajan Venkatesan, Ruben Schwartz, Saad Alobid, Sivanesan Dhandayuthapani
Publikováno v:
Cells
Cells; Volume 7; Issue 5; Pages: 41
Cells, Vol 7, Iss 5, p 41 (2018)
Cells; Volume 7; Issue 5; Pages: 41
Cells, Vol 7, Iss 5, p 41 (2018)
The Murine Double Minute 2 (MDM2) amplification or overexpression has been found in many tumors with high metastatic and angiogenic ability. Our experiments were designed to explore the impact of MDM2 overexpression, specifically on the levels of ang
Autor:
Thanigaivelan Kanagasabai, Appu Rathinavelu, Thiagarajan Venkatesan, Khalid Alhazzani, Saad Alobid, Priya Dondapati, Ali Alaseem
Publikováno v:
Cancer Research. 77:2013-2013
The matrix metalloprotenases (MMPs) are a family of zinc-dependent endopeptidase and have proteolysis activity which found to impact several physiological and pathophysiological conditions including cancer. In cancer, over 20 types of MMPs promote in
Autor:
Thiagarajan Venkatesan, Appu Rathinavelu, Sivanesan Dhandayuthapani, Karna Mangrola, Ali Alaseem, Jason Maragh, Khadija Cheema, Priya Dondapati
Publikováno v:
Cancer Research. 77:4449-4449
MDM2 amplification, which is often seen in different cancer types, indicates that its plays an important role in tumorigenesis and also in cancer metastasis. Amplification of the MDM2 gene correlates with poor prognosis, aggressive growth, and reoccu
Autor:
Ali Alaseem, Thiagarajan Venkatesan, Saad Alobid, Priya Dondapati, Khalid Alhazzani, Appu Rathinavelu
Publikováno v:
Cancer Research. 76:1839-1839
MDM2 gene is a cellular proto-oncogene amplified in 25-40% of all human cancers and regulates cell proliferation, senescence, and apoptosis through targeting p53. It is widely speculated that MDM2 protein is not only responsible for tumorigenesis via