Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Prithi S. Bhathal"'
Autor:
Brendan J. Jenkins, Daniel J. Gough, Prithi S. Bhathal, Thaleia Livis, Alice J. West, Alison C. West, Liang Yu, Mohamed I. Saad, Daniel J. Garama, Jesse J. Balic
Deregulated activation of the latent oncogenic transcription factor STAT3 in many human epithelial malignancies, including gastric cancer, has invariably been associated with its canonical tyrosine phosphorylation and enhanced transcriptional activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f45c44b56603ba8788cdd102c63de96
https://doi.org/10.1158/0008-5472.c.6511035
https://doi.org/10.1158/0008-5472.c.6511035
Autor:
Brendan J. Jenkins, Daniel J. Gough, Prithi S. Bhathal, Thaleia Livis, Alice J. West, Alison C. West, Liang Yu, Mohamed I. Saad, Daniel J. Garama, Jesse J. Balic
File containing essential supplementary figures (7) and tables (3) comprising pre-clinical mouse model and clinical data supporting the role of constitutive pS-STAT3 in gastric cancer. This file also contains additional supplementary methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ad85e798a18234015c0d12c08ac240
https://doi.org/10.1158/0008-5472.22421796.v1
https://doi.org/10.1158/0008-5472.22421796.v1
Autor:
Andrew Hall, Prithi S. Bhathal, Alberto Quaglia, Tu Vinh Luong, Corina Cotoi, Jennifer Watkins
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
The histological distinction between acute and chronic liver injury is a challenging aspect of liver histopathology. It is traditionally based on the interpretation of morphological changes to the extracellular matrix (ECM) at sites of hepatocyte los
Autor:
Tim G St Pierre, Michael J House, Sander J Bangma, Wenjie Pang, Andrew Bathgate, Eng K Gan, Oyekoya T Ayonrinde, Prithi S Bhathal, Andrew Clouston, John K Olynyk, Leon A Adams
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160789 (2016)
Validation of non-invasive methods of liver fat quantification requires a reference standard. However, using standard histopathology assessment of liver biopsies is problematical because of poor repeatability. We aimed to assess a stereological metho
Externí odkaz:
https://doaj.org/article/0c7c74ec362440f7af1973d4c9856c78
Autor:
Virginie Deswaerte, Jesse J. Balic, William Sievert, Alison C. West, Anouk Dev, Kimberley D'Costa, Daniel J. Gough, Mohamed I. Saad, Prithi S. Bhathal, Brendan J. Jenkins, Ruby E. Dawson, Louise McLeod, Alice J. West, Richard L. Ferrero
Publikováno v:
The American Journal of Pathology. 190:1256-1270
Gastric cancer is associated with chronic inflammation (gastritis) triggered by persistent Helicobacter pylori (H. pylori) infection. Elevated tyrosine phosphorylation of the latent transcription factor STAT3 is a feature of gastric cancer, including
Autor:
Jesse J. Balic, Daniel J. Garama, Liang Yu, Prithi S. Bhathal, Alison C. West, Thaleia Livis, Brendan J. Jenkins, Mohamed I. Saad, Alice J. West, Daniel J. Gough
Publikováno v:
Cancer Research. 79:5272-5287
Deregulated activation of the latent oncogenic transcription factor STAT3 in many human epithelial malignancies, including gastric cancer, has invariably been associated with its canonical tyrosine phosphorylation and enhanced transcriptional activit
Autor:
Ansgar W, Lohse, Marcial, Sebode, Prithi S, Bhathal, Andrew D, Clouston, Hans P, Dienes, Dhanpat, Jain, Annette S H, Gouw, Maha, Guindi, Sanjay, Kakar, David E, Kleiner, Till, Krech, Carolin, Lackner, Thomas, Longerich, Romil, Saxena, Luigi, Terracciano, Kay, Washington, Sören, Weidemann, Stefan G, Hübscher, Dina, Tiniakos
Publikováno v:
Liver international : official journal of the International Association for the Study of the LiverREFERENCES. 42(5)
Diagnostic histological criteria for autoimmune hepatitis (AIH) have not been clearly established. Previously published criteria focused mainly on chronic AIH, in which inflammatory changes mainly occur in portal/periportal regions and may not be app
Autor:
Jayati Chakrabarti, Prithi S. Bhathal, Liang Yu, Ruby E. Dawson, Virginie Deswaerte, Masanobu Oshima, Dennis M. Klinman, Brendan J. Jenkins, Linden J. Gearing, Mohamed I. Saad, Jesse J. Balic, Hiroko Oshima, Ke Tang, Patrick Tan, Yonghui Wu, Alice J. West, Yana Zavros, Alison C. West, Beena Kumar
Publikováno v:
Gut. 71(8)
ObjectiveThe absent in melanoma 2 (AIM2) cytosolic pattern recognition receptor and DNA sensor promotes the pathogenesis of autoimmune and chronic inflammatory diseases via caspase-1-containing inflammasome complexes. However, the role of AIM2 in can
Autor:
Michael J House, Eng K Gan, Leon A Adams, Oyekoya T Ayonrinde, Sander J Bangma, Prithi S Bhathal, John K Olynyk, Tim G St Pierre
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59287 (2013)
ObjectivesHepatic steatosis is associated with an increased risk of developing serious liver disease and other clinical sequelae of the metabolic syndrome. However, visual estimates of steatosis from histological sections of biopsy samples are subjec
Externí odkaz:
https://doaj.org/article/9dec11ea90504bc8b8f9ae14ecefa295
Autor:
Marjorie M. Walker, Jonathan Ferrand, Le Son Tran, San Sui Lim, Hassan Mohammad Chaudhry, Gregory T. Moore, Michelle Chonwerawong, Anouk Dev, Mario Milco D'Elios, Prithi S. Bhathal, Dana J. Philpott, Brendan J. Jenkins, Thomas A. Kufer, Chloe Higgins, Richard L. Ferrero, William Sievert
Background & Aims Helicobacter pylori induces strong inflammatory responses that are directed at clearing the infection, but if not controlled, these responses can be harmful to the host. We investigated the immune-regulatory effects of the innate im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc1bf3248d1dfdb41f8b2af4b01528a
http://hdl.handle.net/2158/1245173
http://hdl.handle.net/2158/1245173