Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Pritha Verma"'
Autor:
Yan-Qiao Chen, Jennifer X. Qiao, Pritha Verma, Jin-Quan Yu, Raghavan B. Sunoj, Sukriti Singh, Zhen Wang, Yongwei Wu, Wei Hao
Publikováno v:
Journal of the American Chemical Society. 142:9966-9974
The first example of free amine γ-C(sp3)-H fluorination is realized using 2-hydroxynicotinaldehyde as the transient directing group. A wide range of cyclohexyl and linear aliphatic amines could be fluorinated selectively at the γ-methyl and methyle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbb73944e057dfdddb2c9701a288c9fd
https://doi.org/10.1021/jacs.9b13537
https://doi.org/10.1021/jacs.9b13537
Publikováno v:
Journal of the American Chemical Society. 142:5117-5125
Saturated azacycles are commonly encountered in bioactive compounds and approved therapeutic agents. The development of methods for functionalization of the α-methylene C-H bonds of these highly privileged building blocks is of great importance, esp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f340471b227b6348ef48e3aeae7d83c9
https://doi.org/10.1021/jacs.9b12320
https://doi.org/10.1021/jacs.9b12320
Autor:
Pritha Verma, Erika L. Lucas, Jin-Quan Yu, Tyler G. Saint-Denis, Nikita Chekshin, Nelson Y. S. Lam, Guangrong Meng
Publikováno v:
J Am Chem Soc
The ability to differentiate between highly similar C-H bonds in a given molecule remains a fundamental challenge in organic chemistry. In particular, the lack of sufficient steric and electronic differences between C-H bonds located distal to functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8d882558dde1617e97d3892740e6bd
https://europepmc.org/articles/PMC7485751/
https://europepmc.org/articles/PMC7485751/
Autor:
Yan-Qiao, Chen, Sukriti, Singh, Yongwei, Wu, Zhen, Wang, Wei, Hao, Pritha, Verma, Jennifer X, Qiao, Raghavan B, Sunoj, Jin-Quan, Yu
Publikováno v:
J Am Chem Soc
The first example of free amine γ-C(sp(3))–H fluorination is realized using 2-hydroxynicotinaldehyde as the transient directing group. A wide range of cyclohexyl and linear aliphatic amines could be fluorinated selectively at the γ-methyl and met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48cab3dbb6da8f462a152194df6c203d
https://pubmed.ncbi.nlm.nih.gov/32363869
https://pubmed.ncbi.nlm.nih.gov/32363869
Publikováno v:
J Am Chem Soc
Saturated azacycles are commonly encountered in bioactive compounds and approved therapeutic agents. The development of methods for functionalization of the α-methylene C‒H bonds of these highly privileged building blocks is of great importance, e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ebf2504a5214ca63986bd76eff2a9be4
https://pubmed.ncbi.nlm.nih.gov/32098471
https://pubmed.ncbi.nlm.nih.gov/32098471
Autor:
Shiwei Tao, Marcus E. Farmer, Michael A. Poss, Jennifer X. Qiao, Kap-Sun Yeung, Jin-Quan Yu, Guoqin Xia, Peng Wang, Jun Shi, Peter T. W. Cheng, Pritha Verma
Publikováno v:
Nature. 551:489-493
The directed activation of carbon-hydrogen bonds (C-H) is important in the development of synthetically useful reactions, owing to the proximity-induced reactivity and selectivity that is enabled by coordinating functional groups. Palladium-catalysed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b531d7cb38e622b7d59cb3ceb826c28
https://doi.org/10.1038/nature24632
https://doi.org/10.1038/nature24632
Autor:
Henry F. Schaefer, Bangaru Bhaskararao, C. Athira, Pritha Verma, Megha Anand, Sukriti Singh, Santanu Malakar, Raghavan B. Sunoj, Prafull Prakash
Publikováno v:
Chemical Science
We disclose an intriguing and a potentially general role for one of the most commonly used silver salt additives whose molecular understanding continues to remain rather vague in the contemporary practice of palladium catalysis.
In the contempor
In the contempor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b22ded7d1e6fa5d748b31fb6f4f404
https://pubmed.ncbi.nlm.nih.gov/32110372
https://pubmed.ncbi.nlm.nih.gov/32110372
Autor:
Xiangyang Chen, Jin-Quan Yu, Katherine L. Bay, Pritha Verma, Yi Lu, Hang Shi, Kendall N. Houk, Keita Tanaka, Jiang Weng
Publikováno v:
Nature chemistry
Site-selective functionalization of C–H bonds will ultimately afford chemists transformative tools for editing and constructing complex molecular architectures. Towards this goal, developing strategies to activate C–H bonds that are distal from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf46bbba63f60140f603d6468281f71
https://pubmed.ncbi.nlm.nih.gov/32123338
https://pubmed.ncbi.nlm.nih.gov/32123338
Autor:
Keita Tanaka, Pritha Verma, Kendall N. Houk, Katherine L. Bay, Jin-Quan Yu, Xiangyang Chen, Jiang Weng, Hang Shi, Lu Yi
Site-selective functionalizations of C–H bonds will ultimately afford chemists transformative tools for editing and constructing complex molecular architectures1-4. Towards this goal, developing strategies to activate C–H bonds that are distal fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ffcfb2e700f859824be3bc9d4e55a0f
https://doi.org/10.26434/chemrxiv.8156561
https://doi.org/10.26434/chemrxiv.8156561
Publikováno v:
Nature chemistry
Saturated aza-heterocycles are highly privileged building blocks that are commonly encountered in bioactive compounds and approved therapeutic agents. These N-heterocycles are also incorporated as chiral auxiliaries and ligands in asymmetric synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5858f520349e1169153e2654c68bfad9
http://europepmc.org/articles/PMC5347480
http://europepmc.org/articles/PMC5347480