Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Pritha Ray"'
Autor:
Pratham Phadte, Aniketh Bishnu, Pranay Dey, Manikandan M, Megha Mehrotra, Prerna Singh, Shritama Chakrabarty, Rounak Majumdar, Bharat Rekhi, Malay Patra, Abhijit De, Pritha Ray
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-23 (2024)
Abstract Background The mechanisms enabling dynamic shifts between drug-resistant and drug-sensitive states in cancer cells are still underexplored. This study investigated the role of targeted autophagic protein degradation in regulating ovarian can
Externí odkaz:
https://doaj.org/article/b30acfb5696144008e3ac1ccbfe7940d
Autor:
Aaiyas Mujawar, Pratham Phadte, Ksenia A. Palkina, Nadezhda M. Markina, Ameena Mohammad, Bhushan L. Thakur, Karen S. Sarkisyan, Anastasia V. Balakireva, Pritha Ray, Ilia Yamplosky, Abhijit De
Publikováno v:
Sensors, Vol 23, Iss 17, p 7313 (2023)
This study demonstrates the development of a humanized luciferase imaging reporter based on a recently discovered mushroom luciferase (Luz) from Neonothopanus nambi. In vitro and in vivo assessments showed that human-codon-optimized Luz (hLuz) has si
Externí odkaz:
https://doaj.org/article/9f77f19dccea4e8ea3508824dada6802
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-18 (2021)
Abstract Alterations in key kinases and signaling pathways can fine-tune autophagic flux to promote the development of chemoresistance. Despite empirical evidences of strong association between enhanced autophagic flux with acquired chemoresistance,
Externí odkaz:
https://doaj.org/article/2e3f64040fd34ab1a34a76159cc166c8
Publikováno v:
Indian Journal of Pathology and Microbiology, Vol 63, Iss 5, Pp 64-69 (2020)
In spite of the advent of many high throughput technologies, tumor tissue biomarkers are still the gold standard for diagnosis and prognosis of different malignancies including epithelial ovarian cancer (EOC). EOC is a heterogeneous disease comprised
Externí odkaz:
https://doaj.org/article/8e90e8ddd7f049098213cbd6eb8d1378
Publikováno v:
Bio-Protocol, Vol 12, Iss 3 (2022)
Chemoresistance, the ability of cancer cells to overcome therapeutic interventions, is an area of active research. Studies on intrinsic and acquired chemoresistance have partly succeeded in elucidating some of the molecular mechanisms in this elusive
Externí odkaz:
https://doaj.org/article/4e43f5ac96ec45fc9c8d16b924fb0ab6
Autor:
Sourav Chakraborty, Priti S. Shenoy, Megha Mehrotra, Pratham Phadte, Prerna Singh, Bharat Rekhi, Pritha Ray
Publikováno v:
Diagnostics, Vol 13, Iss 4, p 713 (2023)
Epithelial ovarian cancer (EOC) is the deadliest gynaecological malignancy and the eighth most prevalent cancer in women, with an abysmal mortality rate of two million worldwide. The existence of multiple overlapping symptoms with other gastrointesti
Externí odkaz:
https://doaj.org/article/a28b0b6ce07d45798def57f2893cc9e7
Publikováno v:
Translational Oncology, Vol 14, Iss 11, Pp 101193- (2021)
Therapy induced rewiring of signalling networks often lead to acquirement of platinum-resistance, thereby necessitating the use of non-platinum agents as second-line treatment particularly for epithelial ovarian cancer (EOC). A prior subject-specific
Externí odkaz:
https://doaj.org/article/42110d7c6096421da480424e65919db7
Autor:
Arijit Mal, Amirali B. Bukhari, Ram K. Singh, Aastha Kapoor, Amlan Barai, Ishan Deshpande, Tabassum Wadasadawala, Pritha Ray, Shamik Sen, Abhijit De
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Substantial number of breast cancer (BC) patients undergoing radiation therapy (RT) develop local recurrence over time. During RT therapy, cells can gradually acquire resistance implying adaptive radioresistance. Here we probe the mechanisms underlyi
Externí odkaz:
https://doaj.org/article/b9e10746b91b46fc954afb69f9e70bb7
Autor:
Bhushan Thakur, Pritha Ray
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-14 (2017)
Abstract Background Parallel to complex alteration in molecular and cellular events, enrichment of cancer stem cells (CSC) contributes significantly in deliberation and maintenance of cisplatin resistance. Cisplatin mediated CSC enrichment is well es
Externí odkaz:
https://doaj.org/article/9a09e4a816c34596b689d1fae3ad7a78
Autor:
Bhushan Thakur, Pritha Ray
Publikováno v:
Molecular Oncology, Vol 10, Iss 8, Pp 1283-1295 (2016)
Tumour suppressor p53, a master transcriptional regulator determines cell fate through preferential activation/repression of a myriad of genes during stress. Till date, activation and preferential binding of p53 on different promoters was reported to
Externí odkaz:
https://doaj.org/article/f277ef26cf614f3ab0e22546ea008d08