Výsledky vyhledávání - "Pritchard Dm"

The Nrf2 inhibitor brusatol is a potent antitumour agent in an orthotopic mouse model of colorectal cancer

Autor: Evans, JP, Winiarski, BK, Sutton, PA, Jones, RP, Ressel, L, Duckworth, CA, Pritchard, DM, Lin, ZX, Vicky, FL, Tweedle, EM, Costello, E, Goldring, CE, Copple, IM, Park, BK, Palmer, DH, Kitteringham, NR

Publikováno v: Oncotarget

© Evans et al. Nrf2 is a transcription factor that regulates cellular stress response and irinotecan-metabolising pathways. Its aberrant activity has been reported in a number of cancers, although relatively few studies have explored a role for Nrf2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::c5a0f3d5005d2d5f8d85b80301049a22
http://livrepository.liverpool.ac.uk/3024449/1/25497-1005819-3-PB.pdf

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Netazepide, a gastrin/CCK2 receptor antagonist, can eradicate gastric neuroendocrine tumours in patients with autoimmune chronic atrophic gastritis

Autor: Boyce, M, Moore, AR, Sagatun, L, Parsons, BN, Varro, A, Campbell, F, Fossmark, R, Waldum, HL, Pritchard, DM

Publikováno v: British journal of clinical pharmacology

Netazepide, a gastrin/CCK2 receptor antagonist, once daily for 12 weeks reduced the number of tumours and size of the largest one in 16 patients with autoimmune chronic atrophic gastritis (CAG), achlorhydria, hypergastrinaemia and multiple gastric ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::743f431c6ed579461db112dbd5862ff4

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Hexane Extracts of Calophyllum brasiliense Inhibit the Development of Gastric Preneoplasia in Helicobacter felis Infected INS-Gas Mice

Autor: Lemos, LMS, Miyajima, F, Castilho, GRC, Martins, DTO, Pritchard, DM, Burkitt, MD

Publikováno v: Frontiers in Pharmacology

Objectives: Indigenous Latin American populations have used extracts from Calophyllum brasiliense, a native hardwood, to treat gastrointestinal symptoms for generations. The hexane extract of Calophyllum brasiliense stem bark (HECb) protects against

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::78b2af2dba6b50680ccb2fd5bed09e64

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Circulating galectins -2, -4 and -8 in cancer patients make important contributions to the increased circulation of several cytokines and chemokines that promote angiogenesis and metastasis

Autor: Carrie A. Duckworth, Chen Chen, Jonathan M. Rhodes, Fu B, Pritchard Dm, Lu-Gang Yu

Publikováno v: British Journal of Cancer

Background: Circulating concentrations of the cytokines interleukin-6 (IL-6), granulocyte colony-stimulating factor (G-CSF) and chemokines monocyte chemotatic protein 1 (MCP-1)/CCL2 and growth-regulator oncogene α (GROα)/chemokine C-X-C motif ligan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5741963edd464b6f81f7139052c09052
http://europepmc.org/articles/PMC3915140

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Netazepide, a gastrin/cholecystokinin‐2 receptor antagonist, can eradicate gastric neuroendocrine tumours in patients with autoimmune chronic atrophic gastritis

Autor: Boyce, M, Moore, AR, Sagatun, L, Parsons, BN, Varro, A, Campbell, F, Fossmark, R, Waldum, HL, Pritchard, DM

Publikováno v: British Journal of Clinical Pharmacology

Aims Netazepide, a gastrin/cholecystokinin 2 receptor antagonist, once daily for 12 weeks reduced the number of tumours and size of the largest one in 16 patients with autoimmune chronic atrophic gastritis (CAG), achlorhydria, hypergastrinaemia and m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8926bc7bc8ffab5f49b7f248b72358bb
https://europepmc.org/articles/PMC5306499/

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