Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Pritam K. Sengupta"'
Autor:
Pritam K. Sengupta, Volkhard Lindner, Gangli Liu, Hsiao-Ying Yang, Maria A. Kukuruzinska, Meghan P. Bouchie, Xaralabos Varelas, Basem T Jamal
Publikováno v:
Journal of Biological Chemistry. 288:20217-20227
Oral squamous cell carcinoma (OSCC) is one of the most pernicious malignancies, but the mechanisms underlying its development and progression are poorly understood. One of the key pathways implicated in OSCC is the canonical Wnt/β-catenin signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81dea9307f86c8264776e61ca5c8980
https://doi.org/10.1074/jbc.m113.473785
https://doi.org/10.1074/jbc.m113.473785
Autor:
Meghan P. Bouchie, Mihai Nita-Lazar, Maria A. Kukuruzinska, Zhen-nan Gao, Bakr Amin, Pritam K. Sengupta, Basem T Jamal, Sharuch Jalisi
Publikováno v:
Oral Oncology. 48:523-529
Oral cancer is one of the most aggressive epithelial malignancies, whose incidence is on the rise. Previous studies have shown that in a subset of human oral squamous cell carcinoma (OSCC) tumor specimens, overexpression of the DPAGT1 gene, encoding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7670a23fb81d4e51c374f36ae5793cd1
https://doi.org/10.1016/j.oraloncology.2012.01.010
https://doi.org/10.1016/j.oraloncology.2012.01.010
Publikováno v:
Journal of Biological Chemistry. 281:9260-9270
Our studies indicate that the regulatory factor for X-box (RFX) family proteins repress collagen α2(I) gene (COL1A2) expression (Xu, Y., Wang, L., Buttice, G., Sengupta, P. K., and Smith, B. D. (2003) J. Biol. Chem. 278, 49134–49144; Xu, Y., Wang,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f612c4ec6d5ec157fac666921fe6755f
https://doi.org/10.1074/jbc.m511724200
https://doi.org/10.1074/jbc.m511724200
Publikováno v:
Journal of Biological Chemistry. 280:21004-21014
Collagen type I is composed of three polypeptide chains transcribed from two separate genes (COL1A1 and COL1A2) with different promoters requiring coordinate regulation. Our recent publications, centering on COL1A2 regulation, demonstrate that methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5fb626be44184e66dfa8021a622f7f
https://doi.org/10.1074/jbc.m413191200
https://doi.org/10.1074/jbc.m413191200
Publikováno v:
Journal of Biological Chemistry. 277:24926-24937
The transcription start site of the collagen alpha2(1) gene (COL1A2) has a sequence-specific binding site for a DNA methylation-responsive binding protein called regulatory factor for X-box 1 (RFX1) (Sengupta, P. K., Erhlich, M., and Smith, B. D. (19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc079e73af8b4123216332be4c212e8
https://doi.org/10.1074/jbc.m111712200
https://doi.org/10.1074/jbc.m111712200
Publikováno v:
Journal of Biological Chemistry. 274:36649-36655
DNA methylation inhibits transcription driven by the collagen alpha2(I) promoter and the 5' end of the gene in transient transfection and in vitro transcription assays. DNA-binding proteins in a unique family of ubiquitously expressed proteins, methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636b2682cc1fb43e7a3cd4ed70048718
https://doi.org/10.1074/jbc.274.51.36649
https://doi.org/10.1074/jbc.274.51.36649
Autor:
Pritam K. Sengupta, Barbara D. Smith
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1443:75-89
Our previous studies demonstrated that the collagen alpha2(I) gene is hypermethylated in the promoter/first exon region after chemical transformation and the alpha2(I) promoter/first exon is sensitive to methylation in transfection studies. In this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9ae1d2e068ed91c451d46b70422b98
https://doi.org/10.1016/s0167-4781(98)00188-2
https://doi.org/10.1016/s0167-4781(98)00188-2
Publikováno v:
American Journal of Hematology. 46:169-172
We have studied the effect of site-specific cytosine methylation on the binding of nuclear proteins to the γ-globin promoter region from −71 to −34. This sequence was recently shown to contain a stage selector element responsible for increased t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebef55bad624a6d116177c771e4db6b1
https://doi.org/10.1002/ajh.2830460302
https://doi.org/10.1002/ajh.2830460302
Publikováno v:
Blood. 83:1420-1427
Developmental regulation of globin gene expression may be controlled by developmental stage-specific nuclear proteins that influence interactions between the locus control region and local regulatory sequences near individual globin genes. We previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::742d0b8ff25f73399244ef0501a53379
https://doi.org/10.1182/blood.v83.5.1420.1420
https://doi.org/10.1182/blood.v83.5.1420.1420
Protein N-glycosylation and the Wnt/β-catenin signaling pathways play critical roles in development and cancer. Although N-glycosylation has been shown to influence Wnt signaling through its effects on Wnt ligands, it is unclear whether the Wnt/β-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900c0d8106c308dd4216b3cb9f72d60a
https://europepmc.org/articles/PMC2951190/
https://europepmc.org/articles/PMC2951190/
