Cheminformatics and artificial intelligence for accelerating agrochemical discovery

Autor: Yannick Djoumbou-Feunang, Jeremy Wilmot, John Kinney, Pritam Chanda, Pulan Yu, Avery Sader, Max Sharifi, Scott Smith, Junjun Ou, Jie Hu, Elizabeth Shipp, Dirk Tomandl, Siva P. Kumpatla

Publikováno v: Frontiers in Chemistry, Vol 11 (2023)

The global cost-benefit analysis of pesticide use during the last 30 years has been characterized by a significant increase during the period from 1990 to 2007 followed by a decline. This observation can be attributed to several factors including, bu

Externí odkaz: https://doaj.org/article/33532c831ec64697b2df997d64040383

Information Theory in Computational Biology: Where We Stand Today

Autor: Pritam Chanda, Eduardo Costa, Jie Hu, Shravan Sukumar, John Van Hemert, Rasna Walia

Publikováno v: Entropy, Vol 22, Iss 6, p 627 (2020)

“A Mathematical Theory of Communication” was published in 1948 by Claude Shannon to address the problems in the field of data compression and communication over (noisy) communication channels. Since then, the concepts and ideas developed in Shann

Externí odkaz: https://doaj.org/article/a059fcf1c50a4a30806e5bf379722d94

Gene-based tests of association.

Autor: Hailiang Huang, Pritam Chanda, Alvaro Alonso, Joel S Bader, Dan E Arking

Publikováno v: PLoS Genetics, Vol 7, Iss 7, p e1002177 (2011)

Genome-wide association studies (GWAS) are now used routinely to identify SNPs associated with complex human phenotypes. In several cases, multiple variants within a gene contribute independently to disease risk. Here we introduce a novel Gene-Wide S

Externí odkaz: https://doaj.org/article/54690885618f4c6b97de466b5a371a4b

DeepSort: deep convolutional networks for sorting haploid maize seeds

Autor: John W. Raymond, Balaji Veeramani, Pritam Chanda

Publikováno v: BMC Bioinformatics
BMC Bioinformatics, Vol 19, Iss S9, Pp 1-9 (2018)

Background Maize is a leading crop in the modern agricultural industry that accounts for more than 40% grain production worldwide. THe double haploid technique that uses fewer breeding generations for generating a maize line has accelerated the pace

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c0605b48144a8c034215baf3565d881
http://europepmc.org/articles/PMC6101072

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Autor: Rob M. van Dam, Francis S. Collins, Konstantin Strauch, Raimund Erbel, Rafn Benediktsson, Philippe Froguel, Kyle J. Gaulton, Peter Donnelly, Torben Hansen, Longda Jiang, Lennart C. Karssen, Rona J. Strawbridge, David J. Hunter, Leena Kinnunen, Thomas Meitinger, Michael Stumvoll, Stéphane Cauchi, Ching-Ti Liu, Olga McLeod, Oluf Pedersen, Michael Boehnke, Denis Rybin, Karl Gertow, Tõnu Esko, Bernhard O. Boehm, Sonali Pechlivanis, Bo Isomaa, Anne U. Jackson, Clement Ma, Yingchang Lu, Nicola D. Kerrison, Ruth J. F. Loos, Caroline S. Fox, Chiara Scapoli, Jian'an Luan, Martina Müller-Nurasyid, Domenico Palli, Anke Tönjes, Natalie R. van Zuydam, Neil Robertson, Barbara Thorand, Natalia Pervjakova, Andrew R. Wood, Karin Leander, Unnur Thorsteinsdottir, Sara M. Willems, Karen L. Mohlke, Robert A. Scott, Markus M. Nöthen, Ulf de Faire, Qi Sun, Eric Boerwinkle, Roman Wennauer, Douglas M. Ruderfer, Marika Kaakinen, Nigel W. Rayner, Jaakko Tuomilehto, Nisa M. Maruthur, Richard N. Bergman, Janina S. Ried, Himanshu Chheda, Josée Dupuis, Juan Tajes-Fernandes, Steve E. Humphries, Reedik Mägi, Gonçalo R. Abecasis, B F Voight, David Couper, Cornelia M. van Duijn, Samuli Ripatti, Yeji Lee, Heikki A. Koistinen, Christian Dina, Andres Metspalu, Lu Qi, James S. Pankow, Han Chen, Damiano Baldassarre, Mattias Frånberg, Gerald Steinbach, Inga Prokopenko, Matthias Blüher, Jose C. Florez, Julia Meyer, Niels Grarup, Anders Hamsten, Valeriya Lyssenko, James B. Meigs, Pritam Chanda, Leif Groop, Sarah Edkins, Anubha Mahajan, Gunnar Sigurðsson, Marilyn C. Cornelis, Christian Gieger, Nancy L. Pedersen, Andrew T. Hattersley, Paul W. Franks, Nicholas J. Wareham, Stefan Gustafsson, Katharine R. Owen, Peter Kovacs, Andrew D. Johnson, Lori L. Bonnycastle, Tiinamaija Tuomi, Aurelio Barricarte Gurrea, Tune H. Pers, Eric J.G. Sijbrands, Phoenix Kwan, Emmi Tikkanen, Elisabeth M. van Leeuwen, Stéphane Lobbens, Claudia Langenberg, E. Eury, Thomas W. Mühleisen, Lewin Eisele, Veikko Salomaa, Satu Mӓnnistö, Christian Fuchsberger, Evelin Mihailov, David Altshuler, Timothy M. Frayling, Peter Almgren, Harald Grallert, Hans A. Kestler, Beverley Balkau, Erik Ingelsson, Colin N. A. Palmer, Yvonne T. van der Schouw, Michael Roden, Thomas Sparsø, Karl-Heinz Jöckel, Johan G. Eriksson, Inês Barroso, John D. Eicher, Bengt Sennblad, Bruna Gigante, Andrew D. Morris, Panagiotis Deloukas, Man Li, Allan Linneberg, Astradur B. Hreidarsson, Lars Lannfelt, Elena Tremoli, Liming Liang, Omri Gottesman, Letizia Marullo, Peter S. Chines, Kari Stefansson, Mark I. McCarthy, Andrew P. Morris, Erwin P. Bottinger, Augustine Kong, Torben Jørgensen, Tanya M. Teslovich, Frank B. Hu, Dorothée Thuillier, Peter Kraft, Heiner Boeing, Laura J. Scott, Gudmar Thorleifsson, Lars Lind, John R. B. Perry, Heather M. Stringham, Susanne Moebus, Valgerdur Steinthorsdottir, Cecilia M. Lindgren, Guillaume Charpentier, Eleftheria Zeggini, Leena Peltonen, Loic Yengo, Norman Klopp, Teresa Ferreira, Christian Theil Have, Marit E. Jørgensen

Publikováno v: Scott, R A, Scott, L J, Mägi, R, Marullo, L, Gaulton, K J, Kaakinen, M, Pervjakova, N, Pers, T H, Johnson, A D, Eicher, J D, Jackson, A U, Ferreira, T, Lee, Y, Ma, C, Steinthorsdottir, V, Thorleifsson, G, Qi, L, Van Zuydam, N R, Mahajan, A, Chen, H, Almgren, P, Voight, B F, Grallert, H, Müller-Nurasyid, M, Ried, J S, Rayner, N W, Robertson, N R, Karssen, L C, van Leeuwen, E M, Willems, S M, Fuchsberger, C, Kwan, P, Teslovich, T M, Chanda, P, Li, M, Lu, Y, Dina, C, Thuillier, D, Yengo, L, Jiang, L, Sparso, T, Kestler, H A, Chheda, H, Eisele, L, Gustafsson, S, Frånberg, M, Strawbridge, R J, Benediktsson, R, Hreidarsson, A B, Jørgensen, T & DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium 2017, ' An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans ', Diabetes, vol. 66, no. 11, pp. 2888-2902 . https://doi.org/10.2337/db16-1253
Diabetes 66, 2888-2902 (2017)
Diabetes, 66(11), 2888-2902. American Diabetes Association Inc.
Scott, R A, Scott, L J, Mägi, R, Marullo, L, Gaulton, K J, Kaakinen, M, Pervjakova, N, Pers, T H, Johnson, A D, Eicher, J D, Jackson, A U, Ferreira, T, Lee, Y, Ma, C, Steinthorsdottir, V, Thorleifsson, G, Qi, L, Van Zuydam, N R, Mahajan, A, Chen, H, Almgren, P, Voight, B F, Grallert, H, Müller-nurasyid, M, Ried, J S, Rayner, W N, Robertson, N, Karssen, L C, Van Leeuwen, E M, Willems, S M, Fuchsberger, C, Kwan, P, Teslovich, T M, Chanda, P, Li, M, Lu, Y, Dina, C, Thuillier, D, Yengo, L, Jiang, L, Sparso, T, Kestler, H A, Chheda, H, Eisele, L, Gustafsson, S, Frånberg, M, Strawbridge, R J, Benediktsson, R, Hreidarsson, A B, Kong, A, Sigurðsson, G, Kerrison, N D, Luan, J, Liang, L, Meitinger, T, Roden, M, Thorand, B, Esko, T, Mihailov, E, Fox, C, Liu, C, Rybin, D, Isomaa, B, Lyssenko, V, Tuomi, T, Couper, D J, Pankow, J S, Grarup, N, Have, C T, Jørgensen, M E, Jørgensen, T, Linneberg, A, Cornelis, M C, Van Dam, R M, Hunter, D J, Kraft, P, Sun, Q, Edkins, S, Owen, K R, Perry, J R, Wood, A R, Zeggini, E, Tajes-fernandes, J, Abecasis, G R, Bonnycastle, L L, Chines, P S, Stringham, H M, Koistinen, H A, Kinnunen, L, Sennblad, B, Mühleisen, T W, Nöthen, M M, Pechlivanis, S, Baldassarre, D, Gertow, K, Humphries, S E, Tremoli, E, Klopp, N, Meyer, J, Steinbach, G, Wennauer, R, Eriksson, J G, Mӓnnistö, S, Peltonen, L, Tikkanen, E, Charpentier, G, Eury, E, Lobbens, S, Gigante, B, Leander, K, Mcleod, O, Bottinger, E P, Gottesman, O, Ruderfer, D, Blüher, M, Kovacs, P, Tonjes, A, Maruthur, N M, Scapoli, C, Erbel, R, Jöckel, K, Moebus, S, De Faire, U, Hamsten, A, Stumvoll, M, Deloukas, P, Donnelly, P J, Frayling, T M, Hattersley, A T, Ripatti, S, Salomaa, V, Pedersen, N L, Boehm, B O, Bergman, R N, Collins, F S, Mohlke, K L, Tuomilehto, J, Hansen, T, Pedersen, O, Barroso, I, Lannfelt, L, Ingelsson, E, Lind, L, Lindgren, C M, Cauchi, S, Froguel, P, Loos, R J, Balkau, B, Boeing, H, Franks, P W, Gurrea, A B, Palli, D, Van Der Schouw, Y T, Altshuler, D, Groop, L C, Langenberg, C, Wareham, N J, Sijbrands, E, Van Duijn, C M, Florez, J C, Meigs, J B, Boerwinkle, E, Gieger, C, Strauch, K, Metspalu, A, Morris, A D, Palmer, C N, Hu, F B, Thorsteinsdottir, U, Stefansson, K, Dupuis, J, Morris, A P, Boehnke, M, Mccarthy, M I & Prokopenko, I 2017, ' An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans ', Diabetes, pp. db161253 . https://doi.org/10.2337/db16-1253
Scott, R A, Scott, L J, Mägi, R, Marullo, L, Gaulton, K J, Kaakinen, M, Pervjakova, N, Pers, T H, Johnson, A D, Eicher, J D, Jackson, A U, Ferreira, T, Lee, Y, Ma, C, Steinthorsdottir, V, Thorleifsson, G, Qi, L, Van Zuydam, N R, Mahajan, A, Chen, H, Almgren, P, Voight, B F, Grallert, H, Müller-Nurasyid, M, Ried, J S, Rayner, N W, Robertson, N, Karssen, L C, van Leeuwen, E M, Willems, S M, Fuchsberger, C, Kwan, P, Teslovich, T M, Chanda, P, Li, M, Lu, Y, Dina, C, Thuillier, D, Yengo, L, Jiang, L, Sparso, T, Kestler, H A, Chheda, H, Eisele, L, Gustafsson, S, Frånberg, M, Strawbridge, R J, Benediktsson, R, Jørgensen, M E, Hansen, T & DIAGRAM Consortium 2017, ' An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans ', Diabetes, vol. 66, no. 11, pp. 2888-2902 . https://doi.org/10.2337/db16-1253
Diabetes
Diabetes, 66(11), 2888. American Diabetes Association Inc.
DIABETES

To characterize type 2 diabetes (T2D)-associated variation across the allele frequency spectrum, we conducted a meta-analysis of genome-wide association data from 26,676 T2D case and 132,532 control subjects of European ancestry after imputation usin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d43a331d53d3a1bc806c1e9fb787f732
https://vbn.aau.dk/da/publications/bc27dd82-ce45-4e74-a934-5ef0ac509e8e