Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Priska, Auf der Maur"'
Autor:
Marcel P. Trefny, Nicole Kirchhammer, Priska Auf der Maur, Marina Natoli, Dominic Schmid, Markus Germann, Laura Fernandez Rodriguez, Petra Herzig, Jonas Lötscher, Maryam Akrami, Jane C. Stinchcombe, Michal A. Stanczak, Andreas Zingg, Melanie Buchi, Julien Roux, Romina Marone, Leyla Don, Didier Lardinois, Mark Wiese, Lukas T. Jeker, Mohamed Bentires-Alj, Jérémie Rossy, Daniela S. Thommen, Gillian M. Griffiths, Heinz Läubli, Christoph Hess, Alfred Zippelius
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
The efficacy of T-cell-based cancer immunotherapies can be compromised by T cell exhaustion. Here the authors develop a human ex vivo exhaustion model and, based on a CRISPR-Cas9 screen, identify SNX9 as a regulator of T cell exhaustion, showing that
Externí odkaz:
https://doaj.org/article/fdf4b11832574e5fbfe57578d57e0309
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 6, Pp 1-17 (2022)
Abstract Breast cancer is the most frequent cancer among women, and metastases in distant organs are the leading cause of the cancer‐related deaths. While survival of early‐stage breast cancer patients has increased dramatically, the 5‐year sur
Externí odkaz:
https://doaj.org/article/9a71ac6f12ae43ba8630c0c4a704f717
Autor:
Federica Zilli, Pedro Marques Ramos, Priska Auf der Maur, Charly Jehanno, Atul Sethi, Marie‐May Coissieux, Tobias Eichlisberger, Loïc Sauteur, Adelin Rouchon, Laura Bonapace, Joana Pinto Couto, Roland Rad, Michael Rugaard Jensen, Andrea Banfi, Michael B Stadler, Mohamed Bentires‐Alj
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 4, Pp 1-19 (2021)
Abstract Metastasis is the main cause of deaths related to solid cancers. Active transcriptional programmes are known to regulate the metastatic cascade but the molecular determinants of metastatic colonization remain elusive. Using an inducible pigg
Externí odkaz:
https://doaj.org/article/42ad8c50455f42c9bfe8d2e92e8ddc15
Autor:
Milica Vulin, Charly Jehanno, Atul Sethi, Ana Luísa Correia, Milan M. S. Obradović, Joana Pinto Couto, Marie-May Coissieux, Maren Diepenbruck, Bogdan-Tiberius Preca, Katrin Volkmann, Priska Auf der Maur, Alexander Schmidt, Simone Münst, Loïc Sauteur, Michal Kloc, Marta Palafox, Adrian Britschgi, Vincent Unterreiner, Olaf Galuba, Isabelle Claerr, Sandra Lopez-Romero, Giorgio G. Galli, Daniel Baeschlin, Ryoko Okamoto, Savas D. Soysal, Robert Mechera, Walter P. Weber, Thomas Radimerski, Mohamed Bentires-Alj
Publikováno v:
Oncogene. 41:4459-4473
Plasticity delineates cancer subtypes with more or less favourable outcomes. In breast cancer, the subtype triple-negative lacks expression of major differentiation markers, e.g., estrogen receptor α (ERα), and its high cellular plasticity results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63aa2dd9501f2424f301e979d8bdcf8
https://doi.org/10.1038/s41388-022-02429-0
https://doi.org/10.1038/s41388-022-02429-0
Autor:
Priska Auf der Maur, Heinz Laubli, Alfred Zippelius, Nicole Kirchhammer, Marcel Philipp Trefny
Publikováno v:
Science translational medicine. 14(670)
Immune checkpoint blockade (ICB) has revolutionized cancer treatment. However, resistance to ICB occurs frequently due to tumor-intrinsic alterations or extrinsic factors in the tumor microenvironment. This Viewpoint aims to give an update on recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d27fad58090382ebb1dac80289f470
https://pubmed.ncbi.nlm.nih.gov/36350989
https://pubmed.ncbi.nlm.nih.gov/36350989
Publikováno v:
EMBO Molecular Medicine. 14
Breast cancer is the most frequent cancer among women, and metastases in distant organs are the leading cause of the cancer-related deaths. While survival of early-stage breast cancer patients has increased dramatically, the 5-year survival rate of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff0105dae98fcf05facae6c50088ace
https://doi.org/10.15252/emmm.202114283
https://doi.org/10.15252/emmm.202114283
Autor:
Romain J. Amante, Priska Auf der Maur, Veronica Richina, Atul Sethi, Vytautas Iesmantavicius, Debora Bonenfant, Nicola Aceto, Mohamed Bentires-Alj
Publikováno v:
Journal of Mammary Gland Biology and Neoplasia, 27 (2)
Treatment of metastasis remains a clinical challenge and the majority of breast cancer-related deaths are the result of drug-resistant metastases. The protein tyrosine phosphatase SHP2 encoded by the proto-oncogene PTPN11 promotes breast cancer progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807097728b1a30858a8b656140e41f97
Autor:
Ryoko Okamoto, Luigi Terracciano, Mohamed Bentires-Alj, Marcel P. Trefny, Marcus Vetter, Alfred Zippelius, Joao C. Guimaraes, Walter P. Weber, Katrin Volkmann, Christian Kurzeder, Duvini De Silva, Ana Luísa Correia, Alexander Schmidt, Kirsten D. Mertz, Sandro Bruno, Priska Auf der Maur
The persistence of undetectable disseminated tumour cells (DTCs) after primary tumour resection poses a major challenge to effective cancer treatment1–3. These enduring dormant DTCs are seeds of future metastases, and the mechanisms that switch the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5605845bcb14053a69e34fe5b09cd7
https://edoc.unibas.ch/90861/
https://edoc.unibas.ch/90861/
Autor:
Ana Luísa, Correia, Joao C, Guimaraes, Priska, Auf der Maur, Duvini, De Silva, Marcel P, Trefny, Ryoko, Okamoto, Sandro, Bruno, Alexander, Schmidt, Kirsten, Mertz, Katrin, Volkmann, Luigi, Terracciano, Alfred, Zippelius, Marcus, Vetter, Christian, Kurzeder, Walter Paul, Weber, Mohamed, Bentires-Alj
Publikováno v:
Nature. 594(7864)
The persistence of undetectable disseminated tumour cells (DTCs) after primary tumour resection poses a major challenge to effective cancer treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::98de8ce2e1a2a75b9a13a2478f4e5663
https://pubmed.ncbi.nlm.nih.gov/35469002
https://pubmed.ncbi.nlm.nih.gov/35469002
Autor:
Alexander Schmidt, Joao C. Guimaraes, Christian Kurzeder, Marcus Vetter, Mohamed Bentires-Alj, Alfred Zippelius, Duvini De Silva, Kirsten D. Mertz, Ana Luísa Correia, Walter P. Weber, Marcel P. Trefny, Sandro Bruno, Luigi Terracciano, Katrin Volkmann, Ryoko Okamoto, Priska Auf der Maur
Publikováno v:
Nature. 600:E7-E7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88ecafd49f617f4aa02bb098b80a3645
https://doi.org/10.1038/s41586-021-04104-y
https://doi.org/10.1038/s41586-021-04104-y