Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Priscilla W. Lee"'
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Vitamin D insufficiency during childhood has been linked to the development of multiple sclerosis (MS), typically an adult-onset inflammatory demyelinating disease of the central nervous system (CNS). Since vitamin D was known to have immunoregulator
Externí odkaz:
https://doaj.org/article/3b9bfd14854b4788b6a4cfd4c63e648d
Autor:
Priscilla W. Lee, Amanda Selhorst, Sara Gombash Lampe, Yue Liu, Yuhong Yang, Amy E. Lovett-Racke
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Low vitamin D during childhood is associated with an increased risk of developing multiple sclerosis (MS) as an adult. Given that vitamin D has anti-inflammatory properties, it has been postulated that the relationship between MS and low vitamin D is
Externí odkaz:
https://doaj.org/article/05d07390515342daaa5d8d3ff6dd1ffb
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Identifying molecules that are differentially expressed in encephalitogenic T cells is critical to the development of novel and specific therapies for multiple sclerosis (MS). In this study, IL-3 was identified as a molecule highly expressed in encep
Externí odkaz:
https://doaj.org/article/baf61627f3bc425881c70fd432aa1ec7
Publikováno v:
Frontiers in neurology. 13
Vitamin D insufficiency during childhood has been linked to the development of multiple sclerosis (MS), typically an adult-onset inflammatory demyelinating disease of the central nervous system (CNS). Since vitamin D was known to have immunoregulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d73e1c3c2fbf4fa752ec7af846c9307
https://pubmed.ncbi.nlm.nih.gov/35651353
https://pubmed.ncbi.nlm.nih.gov/35651353
Publikováno v:
European Journal of Immunology. 47:446-453
Transforming growth factor beta (TGF-β) is a pleiotropic cytokine that has been shown to influence the differentiation and function of T cells. The role that TGF-β plays in immune-mediated disease, such as multiple sclerosis (MS), has become a majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb7250d5ad5c84e30ed3c54fcac87ef
https://doi.org/10.1002/eji.201646716
https://doi.org/10.1002/eji.201646716
Autor:
Priscilla W. Lee, Yuhong Yang, Alan J. Smith, Amanda J. Selhorst, Amy E. Lovett-Racke, Michael K. Racke, Yue Liu
The factors that promote the differentiation of pathogenic T cells in autoimmune diseases are poorly defined. Use of genetically modified mice has provided insight into molecules necessary for the development of autoimmunity, but the sum of the data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a320ddaa81b735a8a754739984e5cfc
https://europepmc.org/articles/PMC5621925/
https://europepmc.org/articles/PMC5621925/
Autor:
Yue Liu, A. Minc, Amy E. Lovett-Racke, Priscilla W. Lee, E. Rieser, M. Larson, Yuhong Yang, Patrick K Nuro-Gyina, Wei Pei, R. C. Winger, Michael K. Racke
Publikováno v:
Clinical and Experimental Immunology. 179:108-118
Summary Multiple sclerosis (MS) is an immune-mediated chronic central nervous system (CNS) disease affecting more than 400 000 people in the United States. Myelin-reactive CD4 T cells play critical roles in the formation of acute inflammatory lesions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cda3c9f7ada4d85e824b2ff8530104e
https://doi.org/10.1111/cei.12441
https://doi.org/10.1111/cei.12441
Autor:
Naveen Kanthamneni, Zachary VanGundy, Kevin J. Peine, Tracey L. Papenfuss, D. Probst, Priscilla W. Lee, Eric M. Bachelder, Yuhong Yang, Mary Severin, Kristy M. Ainslie, Amy E. Lovett-Racke, Haiyan Peng, Mireia Guerau-de-Arellano
Publikováno v:
Molecular Pharmaceutics
Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system that can cause loss of motor function and is thought to result, in part, from chronic inflammation due to an antigen-specific T cell immune response. Curren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae28a4a52c019b09b547a613611046e0
https://doi.org/10.1021/mp4005172
https://doi.org/10.1021/mp4005172
Autor:
Amy E. Lovett-Racke, Saba I. Aqel, Wei Pei, Yue Liu, Patrick K Nuro-Gyina, Marissa C. Granitto, Jian Zhang, Elizabeth L Rieser, Michael K. Racke, Yuhong Yang, Priscilla W. Lee
Publikováno v:
Journal of Neuroinflammation
Background Multiple sclerosis (MS) is a chronic CNS autoimmune disease characterized by inflammation, demyelination, and neuronal degeneration, where myelin-specific CD4 T cells play critical roles in the formation of acute MS lesions and disease pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0349f85640dede061c9deb396967f3
https://doi.org/10.1186/s12974-016-0768-3
https://doi.org/10.1186/s12974-016-0768-3
Autor:
Priscilla W. Lee, Yue Liu, Yuhong Yang, Wei Pei, Amanda J. Selhorst, Mireia Guerau-de-Arellano, Mary Severin, Matthew Gormley, Amy E. Lovett-Racke, Michael K. Racke
Publikováno v:
Brain : a journal of neurology. 139(Pt 6)
Transforming growth factor beta (TGFβ) signalling is critical for regulatory T cell development and function, and regulatory T cell dysregulation is a common observation in autoimmune diseases, including multiple sclerosis. In a comprehensive miRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2c592a4c69babe133af35da1050adc
https://pubmed.ncbi.nlm.nih.gov/27190026
https://pubmed.ncbi.nlm.nih.gov/27190026