Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Priscilla T. Y. Law"'
Autor:
Chuqing Zhang, Yunjing Luo, Rugang Zhong, Priscilla T. Y. Law, Siaw Shi Boon, Zigui Chen, Chi-Hang Wong, Paul K. S. Chan
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Human papillomavirus (HPV) is an etiological agent of cervical cancer. Yet co-factors are believed to be involved in HPV-mediated carcinogenesis. Polycyclic aromatic hydrocarbons (PAHs) are considered as one of these co-factors. E
Externí odkaz:
https://doaj.org/article/e15305ef846c4bf68ba7440faa5f5559
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Type 2 diabetes (T2D) is associated with increased risk of cancers. In this connection, we previously demonstrated the promoting effect of diabetes on HPV-associated carcinogenesis using a xenograft model in db/db diabetic mice. The underlyi
Externí odkaz:
https://doaj.org/article/215cb506569d4afd9eb21f6ffa6b63db
Data from Re-Expression of Transcription Factor ATF5 in Hepatocellular Carcinoma Induces G2-M Arrest
Autor:
Nathalie Wong, Paul B-S. Lai, Priscilla T-Y. Law, Kathy Y-Y. Chan, Wai-Ki Ip, Jennifer W-M. Gho
Transcription factors represent an important class of genes that play key roles in controlling cellular proliferation, cell cycle modulation, and attractive targets for cancer therapy. Here, we report on the novel finding of common ATF5 down-regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5107fb2a9d44b4c4687241cf14eb47b6
https://doi.org/10.1158/0008-5472.c.6496536.v1
https://doi.org/10.1158/0008-5472.c.6496536.v1
Autor:
Siaw Shi Boon, Tsz On Lai, Priscilla T. Y. Law, Lawrence Banks, Zigui Chen, Paul K.S. Chan, Miranda Thomas
Publikováno v:
Journal of General Virology. 100:484-496
Human papillomavirus (HPV) infection contributes to virtually all cases of cervical cancer, the fourth most common cancer affecting women worldwide. The oncogenicity of HPV is mainly attributable to the E6 and E7 oncoproteins. HPV-52 is the seventh m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102d3a896fa21156d3b49142522c11c6
https://doi.org/10.1099/jgv.0.001222
https://doi.org/10.1099/jgv.0.001222
Autor:
Miranda Thomas, Lawrence Banks, Apple C.M. Yeung, Jin Yan Lim, Siaw Shi Boon, Zigui Chen, Priscilla T. Y. Law, Chichao Xia, Paul K.S. Chan
Publikováno v:
Journal of Virology
Epidemiological studies have revealed that a wild-type variant of HPV58 carrying an E7 variation, T20I/G63S (V1), is associated with a higher risk of cervical cancer. We previously reported that this increased oncogenicity could be the result of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634dcd23df7f36f006e9696528cf5d3f
https://pubmed.ncbi.nlm.nih.gov/31996427
https://pubmed.ncbi.nlm.nih.gov/31996427
Autor:
Grace Py Cheung, Chenghua Hu, Raymond Wm Lung, Miranda Thomas, David Pim, Paul K.S. Chan, Priscilla T. Y. Law, Siaw Shi Boon, Wendy C. S. Ho, Lawrence Banks, Zigui Chen, Paola Massimi
Publikováno v:
Journal of Cellular and Molecular Medicine
Human papillomavirus 58 (HPV58) ranks the second or third in East Asian cervical cancers. Current studies on HPV58 are scarce and focus on the prototype. Previously, we identified the three most common circulating HPV58 E7 strains contained amino aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc548d5cfe14b7d900ad87e7ae58e87e
https://pubmed.ncbi.nlm.nih.gov/30575267
https://pubmed.ncbi.nlm.nih.gov/30575267
Autor:
Matthew T. V. Chan, Lin Zhang, Priscilla T. Y. Law, William K.K. Wu, Yuchen Zhang, Jun Yu, Shan Zhao, Sunny H. Wong
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
MicroRNAs are frequently dysregulated in human neoplasms, including gastrointestinal cancers. Nevertheless, the global influence of microRNA dysregulation on cellular signaling is still unknown. Here we sought to elucidate cellular signaling dysregul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e024b921379fb1c0d0eb23429510842d
https://doi.org/10.1038/s41598-018-21573-w
https://doi.org/10.1038/s41598-018-21573-w
Autor:
Priscilla T. Y. Law, Martin C.W. Chan, Rob DeSalle, Paul K.S. Chan, Zigui Chen, Robert D. Burk, Siaw Shi Boon, Wendy C. S. Ho
Publikováno v:
Journal of Virology
Human papillomavirus 58 (HPV58) is found in 10 to 18% of cervical cancers in East Asia but is rather uncommon elsewhere. The distribution and oncogenic potential of HPV58 variants appear to be heterogeneous, since the E7 T20I/G63S variant is more pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c23ef4dbb9570a3750fa9017a0b13f2
https://doi.org/10.1128/jvi.01285-17
https://doi.org/10.1128/jvi.01285-17
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports
Type 2 diabetes (T2D) is associated with increased risk of cancers. In this connection, we previously demonstrated the promoting effect of diabetes on HPV-associated carcinogenesis using a xenograft model in db/db diabetic mice. The underlying mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5151c4377271a50116056633b803b05
Deep sequencing of small RNA transcriptome reveals novel non-coding RNAs in hepatocellular carcinoma
Autor:
Hao Qin, Anthony W.H. Chan, Keng Po Lai, Arthur K.K. Ching, Mian He, Priscilla T. Y. Law, Raymond W.M. Lung, Nathalie Wong, Ting-Fung Chan, Ngai Na Co
Publikováno v:
Journal of Hepatology. 58:1165-1173
Background & Aims Small non-coding RNAs (ncRNA) are increasingly recognized to play important roles in tumorigenesis. With the advent of deep sequencing, efforts have been put forth to profile the miRNome in a number of human malignancies. However, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fed5cf1b9bb48e1e33651b6159e0aa8
https://doi.org/10.1016/j.jhep.2013.01.032
https://doi.org/10.1016/j.jhep.2013.01.032