Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Priscilla Segges"'
1
Akademický článek
Revisiting the Tissue Microenvironment of Infectious Mononucleosis: Identification of EBV Infection in T Cells and Deep Characterization of Immune Profiles
Autor: Mário Henrique M. Barros, Gabriela Vera-Lozada, Priscilla Segges, Rocio Hassan, Gerald Niedobitek
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
To aid understanding of primary EBV infection, we have performed an in depth analysis of EBV-infected cells and of local immune cells in tonsils from infectious mononucleosis (IM) patients. We show that EBV is present in approximately 50% of B-cells
Externí odkaz: https://doaj.org/article/44cf3fe5704b4dafa4138b81836d60b1
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2
Akademický článek
Interleukin 10 (IL10) proximal promoter polymorphisms beyond clinical response in classical Hodgkin lymphoma: Exploring the basis for the genetic control of the tumor microenvironment
Autor: Gabriela Vera-Lozada, Carolina Minnicelli, Priscilla Segges, Gustavo Stefanoff, Flavia Kristcevic, Joaquin Ezpeleta, Elizabeth Tapia, Gerald Niedobitek, Mário Henrique M. Barros, Rocio Hassan
Publikováno v: OncoImmunology, Vol 7, Iss 5 (2018)
Interleukin-10 (IL10) is an immune regulatory cytokine. Single nucleotide polymorphisms (SNPs) in IL10 promoter have been associated with prognosis in adult classical Hodgkin lymphoma (cHL). We analyzed IL10 SNPs −1082 and −592 in respect of ther
Externí odkaz: https://doaj.org/article/843e6e7b40c946a988e416fd87f7be58
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3
Akademický článek
Targeting Hodgkin and Reed–Sternberg Cells with an Inhibitor of Heat-Shock Protein 90: Molecular Pathways of Response and Potential Mechanisms of Resistance
Autor: Priscilla Segges, Stephany Corrêa, Bárbara Du Rocher, Gabriela Vera-Lozada, Flavia Krsticevic, Debora Arce, Cinthya Sternberg, Eliana Abdelhay, Rocio Hassan
Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 3, p 836 (2018)
Classical Hodgkin lymphoma (cHL) cells overexpress heat-shock protein 90 (HSP90), an important intracellular signaling hub regulating cell survival, which is emerging as a promising therapeutic target. Here, we report the antitumor effect of celastro
Externí odkaz: https://doaj.org/article/170a1595ffe94450915176066c13ed42
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4
Akademický článek
Macrophage polarization reflects T cell composition of tumor microenvironment in pediatric classical Hodgkin lymphoma and has impact on survival.
Autor: Mário H M Barros, Priscilla Segges, Gabriela Vera-Lozada, Rocio Hassan, Gerald Niedobitek
Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0124531 (2015)
Macrophages have been implicated in the pathogenesis of classical Hodgkin lymphoma (cHL) and have been suggested to have a negative impact on outcome. Most studies addressing the role of macrophages in cHL have relied on identification of macrophages
Externí odkaz: https://doaj.org/article/fe5882a79a13405b82e0d7614fcfa1c7
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6
Pathway-focused gene expression profiles and immunohistochemistry detection identify contrasting association of caspase 3 (CASP3) expression with prognosis in pediatric classical Hodgkin lymphoma
Autor: Claudio Gustavo Stefanoff, Gerald Niedobitek, Priscilla Segges, Gabriela Vera-Lozada, Mário Henrique M. Barros, Rocio Hassan
Publikováno v: Hematological Oncology. 36:663-670
The search for clinically relevant molecular markers in classical Hodgkin lymphoma (cHL) is hampered by the histopathological complexity of the disease, resulting from the admixture of a small number of neoplastic Hodgkin and Reed-Sternberg (H-RS) ce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5679418d9f111a85d1df787af8548d12
https://doi.org/10.1002/hon.2523
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8
Targeting hodgkin and reed–sternberg cells with an inhibitor of heat-shock protein 90: Molecular pathways of response and potential mechanisms of resistance
Autor: Rocio Hassan, Gabriela Vera-Lozada, Débora Pamela Arce, Stephany Corrêa, Flavia Krsticevic, Priscilla Segges, Bárbara Du Rocher, Eliana Abdelhay, Cinthya Sternberg
Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 3, p 836 (2018)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 19; Issue 3; Pages: 836
Classical Hodgkin lymphoma (cHL) cells overexpress heat-shock protein 90 (HSP90), an important intracellular signaling hub regulating cell survival, which is emerging as a promising therapeutic target. Here, we report the antitumor effect of celastro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe8ea7ff47bdfe9b2114f2ce4f86d62d
http://www.mdpi.com/1422-0067/19/3/836
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9
Genetic Markers Used for Risk Stratification in Multiple Myeloma
Autor: Priscilla Segges, Esteban Braggio
Publikováno v: Genetics Research International
Genetics Research International, Vol 2011 (2011)
While no specific genetic markers are required in the diagnosis of multiple myeloma (MM), multiple genetic abnormalities and gene signatures are used in disease prognostication and risk stratification. This is particularly important for the adequate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f00d1c6526ef1072665c69753512c4
https://doi.org/10.4061/2011/798089
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10
Interleukin 10(IL10) proximal promoter polymorphisms beyond clinical response in classical Hodgkin lymphoma: Exploring the basis for the genetic control of the tumor microenvironment
Autor: Joaquín Ezpeleta, Carolina Minnicelli, Elizabeth Tapia, Gustavo Stefanoff, Flavia Kristcevic, Rocio Hassan, Gerald Niedobitek, Mário Henrique M. Barros, Priscilla Segges, Gabriela Vera-Lozada
Publikováno v: OncoImmunology, Vol 7, Iss 5 (2018)
Oncoimmunology
Interleukin-10 (IL10) is an immune regulatory cytokine. Single nucleotide polymorphisms (SNPs) in IL10 promoter have been associated with prognosis in adult classical Hodgkin lymphoma (cHL). We analyzed IL10 SNPs −1082 and −592 in respect of ther
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ff52ce56434656bb710ee567411123
https://doi.org/10.1080/2162402x.2017.1389821
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