Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Priscilla K Cooper"'
Autor:
Sander Barnhoorn, Lieneke M Uittenboogaard, Dick Jaarsma, Wilbert P Vermeij, Maria Tresini, Michael Weymaere, Hervé Menoni, Renata M C Brandt, Monique C de Waard, Sander M Botter, Altaf H Sarker, Nicolaas G J Jaspers, Gijsbertus T J van der Horst, Priscilla K Cooper, Jan H J Hoeijmakers, Ingrid van der Pluijm
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004686 (2014)
As part of the Nucleotide Excision Repair (NER) process, the endonuclease XPG is involved in repair of helix-distorting DNA lesions, but the protein has also been implicated in several other DNA repair systems, complicating genotype-phenotype relatio
Externí odkaz:
https://doaj.org/article/2627a48029944382a7b41ce43b35c0ba
Autor:
Eric Campeau, Victoria E Ruhl, Francis Rodier, Corey L Smith, Brittany L Rahmberg, Jill O Fuss, Judith Campisi, Paul Yaswen, Priscilla K Cooper, Paul D Kaufman
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6529 (2009)
The ability to express or deplete proteins in living cells is crucial for the study of biological processes. Viral vectors are often useful to deliver DNA constructs to cells that are difficult to transfect by other methods. Lentiviruses have the add
Externí odkaz:
https://doaj.org/article/4f722a938c074f44af58f8c1f007f6a7
Autor:
Jill O Fuss, Priscilla K Cooper
Publikováno v:
PLoS Biology, Vol 4, Iss 6, p e203 (2006)
Externí odkaz:
https://doaj.org/article/7a3be525009d434aba2116570ec87354
Autor:
Alexandra C. Willcox, Jack D. Griffith, Shuai Jiang, Altaf H. Sarker, Priscilla K. Cooper, Albino Bacolla, Clifford Ng, Mai Zong Her, John A. Tainer, Daniel J. Rosenberg, Aye C. Thwin, Andrew S. Arvai, Miaw Sheue Tsai, Michal Hammel, Kelly S. Trego, Alan G. Raetz, Brian Shih, Susan E. Tsutakawa, David S. Shin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance DNA repair is essential to life and to avoidance of genome instability and cancer. Xeroderma pigmentosum group G (XPG) protein acts in multiple DNA repair pathways, both as an active enzyme and as a scaffold for coordinating with other r
Publikováno v:
Prog Biophys Mol Biol
Cell survival largely depends on the faithful maintenance of genetic material since genomic DNA is constantly exposed to genotoxicants from both endogenous and exogenous sources. The evolutionarily conserved base excision repair (BER) pathway is crit
Autor:
Antoine M. Snijders, Weiguo Zhang, Suzaynn F. Schick, Kelly S. Trego, Altaf H. Sarker, Jian-Hua Mao, Priscilla K. Cooper, Bo Hang, Peyton Jacob
Publikováno v:
Environ Mol Mutagen
Thirdhand cigarette smoke (THS) is a newly described toxin that lingers in the indoor environment long after cigarettes have been extinguished. Emerging results from both cellular and animal model studies suggest that THS is a potential human health
Autor:
Jan H.J. Hoeijmakers, Priscilla K. Cooper, Brian Shih, Ann C. Parplys, Miaw Sheue Tsai, Torsten Groesser, Kelly S. Trego, Janice M. Pluth, Ayesu Hlaing, Michael R. Nelson, Weixing Zhao, Patrick Sung, Claudia Wiese, Albert R. Davalos, Björn Rydberg, Judith Campisi
Publikováno v:
Trego, K S, Groesser, T, Davalos, A R, Parplys, A C, Zhao, W, Nelson, M R, Hlaing, A, Shih, B, Rydberg, B, Pluth, J M, Tsai, M-S, Hoeijmakers, J H J, Sung, P, Wiese, C, Campisi, J & Cooper, P K 2016, ' Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability ', Molecular Cell, vol. 61, pp. 535–546 . https://doi.org/10.1016/j.molcel.2015.12.026
Molecular cell, vol 61, iss 4
Trego, KS; Groesser, T; Davalos, AR; Parplys, AC; Zhao, W; Nelson, MR; et al.(2016). Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability. Molecular Cell, 61(4), 535-546. doi: 10.1016/j.molcel.2015.12.026. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/2618t9h0
Molecular Cell, 61(4), 535-546. Cell Press
Molecular cell, vol 61, iss 4
Trego, KS; Groesser, T; Davalos, AR; Parplys, AC; Zhao, W; Nelson, MR; et al.(2016). Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability. Molecular Cell, 61(4), 535-546. doi: 10.1016/j.molcel.2015.12.026. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/2618t9h0
Molecular Cell, 61(4), 535-546. Cell Press
© 2016 Elsevier Inc. XPG is a structure-specific endonuclease required for nucleotide excision repair, and incision-defective XPG mutations cause the skin cancer-prone syndrome xeroderma pigmentosum. Truncating mutations instead cause the neurodevel
Autor:
Priscilla K. Cooper, Erica Werner, Zhentian Li, William S. Dynan, Anita H. Corbett, Jason A. Shah, Kelly S. Trego, Sara W. Leung, Suresh S. Ramalingam, Altaf H. Sarker, Kristin L. Limpose, Paul W. Doetsch
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 46, iss 9
Limpose, KL; Trego, KS; Li, Z; Leung, SW; Sarker, AH; Shah, JA; et al.(2018). Overexpression of the base excision repair NTHL1 glycosylase causes genomic instability and early cellular hallmarks of cancer.. Nucleic acids research, 46(9), 4515-4532. doi: 10.1093/nar/gky162. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/8dj522x9
Nucleic acids research, vol 46, iss 9
Limpose, KL; Trego, KS; Li, Z; Leung, SW; Sarker, AH; Shah, JA; et al.(2018). Overexpression of the base excision repair NTHL1 glycosylase causes genomic instability and early cellular hallmarks of cancer.. Nucleic acids research, 46(9), 4515-4532. doi: 10.1093/nar/gky162. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/8dj522x9
Base excision repair (BER), which is initiated by DNA N-glycosylase proteins, is the frontline for repairing potentially mutagenic DNA base damage. The NTHL1 glycosylase, which excises DNA base damage caused by reactive oxygen species, is thought to
Autor:
Susan E. Tsutakawa, Peter Thompson, Altaf H. Sarker, Christopher G. Tomlinson, L. David Finger, Scott Classen, Andrew S. Arvai, Jane A. Grasby, Brian R. Chapados, John A. Tainer, Priscilla K. Cooper, Binghui Shen, Grant Guenther
Publikováno v:
Cell. 145:198-211
SummaryFlap endonuclease (FEN1), essential for DNA replication and repair, removes RNA and DNA 5′ flaps. FEN1 5′ nuclease superfamily members acting in nucleotide excision repair (XPG), mismatch repair (EXO1), and homologous recombination (GEN1)
Autor:
Janice M. Pluth, Priscilla K. Cooper, Björn Rydberg, Vikky Yamazaki, Brian Cooper, Cordula U. Kirchgessner
Publikováno v:
DNA Repair. 7:108-118
NBS1-deficient cells exhibit pronounced radiosensitivity and defects in chromosome integrity after ionizing radiation (IR) exposure, yet show only a minor defect in DNA double-strand break (DSB) rejoining, leaving an as yet unresolved enigma as to th