Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Priscilla Jaichander"'
Autor:
Karen M. Chapman, Gerardo A. Medrano, Priscilla Jaichander, Jaideep Chaudhary, Alexandra E. Waits, Marcelo A. Nobrega, James M. Hotaling, Carole Ober, F. Kent Hamra
Publikováno v:
Cell Reports, Vol 10, Iss 11, Pp 1828-1835 (2015)
Organisms with targeted genomic modifications are efficiently produced by gene editing in embryos using CRISPR/Cas9 RNA-guided DNA endonuclease. Here, to facilitate germline editing in rats, we used CRISPR/Cas9 to catalyze targeted genomic mutations
Externí odkaz:
https://doaj.org/article/3636e9614fd349e99ff5d4fa5d2528d2
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 10, Pp 2142-2148 (2008)
Low-dose aspirin therapy has become a standard in the treatment of cardiovascular diseases. Aspirin has been shown to inhibit atherosclerosis in mouse models. To determine the mechanisms by which aspirin might inhibit atherosclerosis, we incubated HE
Externí odkaz:
https://doaj.org/article/705cebddafdd4c4e9c63235839d57def
Autor:
Akansha M. Shah, Lei Guo, Maria Gabriella Morales, Priscilla Jaichander, Kenian Chen, Huocong Huang, Karla Cano Hernandez, Lin Xu, Rhonda Bassel-Duby, Eric N. Olson, Ning Liu
Publikováno v:
Cancer Research. 83:4750-4750
Rhabdomyosarcoma (RMS) is a common soft tissue sarcoma in children that resembles the developing skeletal muscle. Unlike normal muscle cells, RMS cells fail to differentiate despite expression of the myogenic determination protein MYOD. The TWIST2 tr
Autor:
Akansha Shah, Lei Guo, Priscilla Jaichander, Kenian Chen, Karla Cano Hernandez, Lin Xu, Rhonda Bassel-Duby, Eric Olson, Ning Liu
Publikováno v:
Cancer Research. 82:6193-6193
Rhabdomyosarcoma (RMS) is an aggressive pediatric soft tissue sarcoma of myoblast origin. RMS tumors are unable to terminally differentiate into syncytial muscle despite elevated expression of the muscle master regulators, MyoD and Myf5. Fusion-posit
Autor:
Rhonda Bassel-Duby, Dileep Karri, Efrain Sanchez-Ortiz, Ning Liu, Eric N. Olson, Stephen Li, Priscilla Jaichander
Publikováno v:
Dev Cell
We previously identified a unique population of interstitial muscle progenitors, marked by expression of the Twist2 transcription factor, which fuses specifically to type IIb/x fast-twitch myofibers. Tw2+ progenitors are distinct from satellite cells
Autor:
Rhonda Bassel-Duby, Yichi Zhang, Spencer D. Barnes, Stephen Li, Eric N. Olson, Yanbin Zheng, Stephen X. Skapek, Lin Xu, Kenian Chen, Ning Liu, Mohammed Hassan, Venkat S. Malladi, Priscilla Jaichander
Publikováno v:
Genesdevelopment. 33(11-12)
Rhabdomyosarcoma (RMS) is an aggressive pediatric cancer composed of myoblast-like cells. Recently, we discovered a unique muscle progenitor marked by the expression of the Twist2 transcription factor. Genomic analyses of 258 RMS patient tumors uncov
Autor:
Jaideep Chaudhary, John M. Shelton, Gerardo A. Medrano, Xian Jin Xie, Erik J. Plautz, F. Kent Hamra, Ashutosh Pudasaini, Frauke Ackermann, Manvendra K. Singh, Craig C. Garner, James A. Richardson, Priscilla Jaichander, Levi B. Good, Heather M. Powell, Zsuzsanna Izsvák, Christine Braun, Zoltán Ivics, Karen M. Chapman
Successful sexual reproduction involves complex, genetically encoded interplay between animal physiology and behavior. The rat provides a highly fecund mammalian model for studying how the brain impacts reproduction. Here, we report a forward genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b427b18937b90eecb4ce658c09ff3ab6
https://doi.org/10.1101/405985
https://doi.org/10.1101/405985
Autor:
Venkat S. Malladi, Eric N. Olson, Miao Cui, Yi Li Min, Rhonda Bassel-Duby, Svetlana Bezprozvannaya, Zhaoning Wang, Efrain Sanchez-Ortiz, Ning Liu, Priscilla Jaichander
Twist transcription factors function as ancestral regulators of mesodermal cell fates in organisms ranging from Drosophila to mammals. Through lineage tracing of Twist2 (Tw2)-expressing cells with tamoxifen-inducible Tw2-CreERT2 and tdTomato (tdTO) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd7f00b1322762804b9a4b5726ef2fe
https://europepmc.org/articles/PMC6130356/
https://europepmc.org/articles/PMC6130356/
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 10, Pp 2142-2148 (2008)
Low-dose aspirin therapy has become a standard in the treatment of cardiovascular diseases. Aspirin has been shown to inhibit atherosclerosis in mouse models. To determine the mechanisms by which aspirin might inhibit atherosclerosis, we incubated HE
Autor:
Karen M. Chapman, Timothy E. Richardson, F. Kent Hamra, Heather M. Powell, Jaideep Chaudhary, Priscilla Jaichander, Shadaan Abid
Publikováno v:
Biology of Reproduction. 90
In mammalian testes, ‘‘A-single’’ spermatogonia function as stem cells that sustain sperm production for fertilizing eggs. Yet, it is not understood how cellular niches regulate the developmental fate of A-single spermatogonia. Here, immunola