Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Priscilla D. Negraes"'
Autor:
Wei Wu, Hang Yao, Priscilla D. Negraes, Juan Wang, Cleber A. Trujillo, Janaina S. de Souza, Alysson R. Muotri, Gabriel G. Haddad
Publikováno v:
Neurobiology of Disease, Vol 174, Iss , Pp 105882- (2022)
Early epilepsy is a prominent feature in patients with CDKL5-deficiency disorder (CDD). The underlying mechanism for excessive excitability in CDD is largely unknown. The brain organoid model has been recently developed to resemble many critical feat
Externí odkaz:
https://doaj.org/article/8d08b672563647ba9ad54e12609b20dd
Autor:
Hang Yao, Wei Wu, Ines Cerf, Helen W. Zhao, Juan Wang, Priscilla D. Negraes, Alysson R. Muotri, Gabriel G. Haddad
Publikováno v:
Stem Cell Research, Vol 49, Iss , Pp 102065- (2020)
Prenatal opioids exposure can lead to both neonatal abstinence syndrome in newborns and neurological deficits later in life. Although opioids have been well studied in general, the cellular and molecular mechanisms by which opioids affect human fetal
Externí odkaz:
https://doaj.org/article/a82fb868c6ac4292b5c7b256e02446f7
Autor:
Wei Wu, Hang Yao, Ila Dwivedi, Priscilla D. Negraes, Helen W. Zhao, Juan Wang, Cleber A. Trujillo, Alysson R. Muotri, Gabriel G. Haddad
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Accumulating evidence has suggested that prenatal exposure to methadone causes multiple adverse effects on human brain development. Methadone not only suppresses fetal neurobehavior and alters neural maturation, but also leads to long-term neurologic
Externí odkaz:
https://doaj.org/article/3a3c6875220a4ca4889b7a2443c0092e
Publikováno v:
Cell Transplantation, Vol 24 (2015)
The kallikrein-kinin system (KKS) is an endogenous pathway involved in many biological processes. Although primarily related to blood pressure control and inflammation, its activation goes beyond these effects. Neurogenesis and neuroprotection might
Externí odkaz:
https://doaj.org/article/4eeaf60f34aa40a4bcf6b772c5358e4b
Autor:
Jason W. Adams, Priscilla D. Negraes, Justin Truong, Timothy Tran, Ryan A. Szeto, Bruno S. Guerra, Roberto H. Herai, Carmen Teodorof-Diedrich, Stephen A. Spector, Miguel Del Campo, Kenneth L. Jones, Alysson R. Muotri, Cleber A. Trujillo
Publikováno v:
Molecular psychiatry, vol 28, iss 4
Prenatal alcohol exposure is the foremost preventable etiology of intellectual disability and leads to a collection of diagnoses known as Fetal Alcohol Spectrum Disorders (FASD). Alcohol (EtOH) impacts diverse neural cell types and activity, but the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdcf37e74144bcc2580b458a0fb9612e
https://escholarship.org/uc/item/6sr863r5
https://escholarship.org/uc/item/6sr863r5
Publikováno v:
Semin Cell Dev Biol
Gene expression comprises a diverse array of enzymes, proteins, non-coding transcripts, and cellular structures to guide the transfer of genetic information to its various final products. In the brain, the coordination among genes, or lack thereof, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eff226bfd73b8bf89c77bffca1507d8
https://doi.org/10.1016/j.semcdb.2020.09.004
https://doi.org/10.1016/j.semcdb.2020.09.004
Autor:
Alysson R. Muotri, Jonathan D. Lautz, Nicholas Liang, Ryan Szeto, John R. Yates, Roberto H. Herai, Gabriel G. Haddad, Wei Wu, Timothy Tran, Salvador Martinez de Bartolome, Nam-Kyung Yu, Cleber A. Trujillo, Jolene K. Diedrich, Priscilla D. Negraes, Justin Truong, Ellius Kwok, Daniel B. McClatchy, Stephen E. P. Smith, Hang Yao
Publikováno v:
Molecular Psychiatry
Molecular psychiatry, vol 26, iss 11
Molecular psychiatry, vol 26, iss 11
Early-onset epileptic encephalopathies are severe disorders often associated with specific genetic mutations. In this context, the CDKL5 deficiency disorder (CDD) is a neurodevelopmental condition characterized by early-onset seizures, intellectual d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228e85f28c4d5078acf2826c14abfa58
http://europepmc.org/articles/PMC8531162
http://europepmc.org/articles/PMC8531162
Autor:
Jason W, Adams, Priscilla D, Negraes, Justin, Truong, Timothy, Tran, Ryan A, Szeto, Bruno S, Guerra, Roberto H, Herai, Carmen, Teodorof-Diedrich, Stephen A, Spector, Miguel, Del Campo, Kenneth L, Jones, Alysson R, Muotri, Cleber A, Trujillo
Publikováno v:
Molecular psychiatry.
Prenatal alcohol exposure is the foremost preventable etiology of intellectual disability and leads to a collection of diagnoses known as Fetal Alcohol Spectrum Disorders (FASD). Alcohol (EtOH) impacts diverse neural cell types and activity, but the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a134a2678331c719fba21e2f43d058df
https://pubmed.ncbi.nlm.nih.gov/36385168
https://pubmed.ncbi.nlm.nih.gov/36385168
Autor:
Jonathan D. Lautz, Sebastian Preissl, Roberto H. Herai, Emily C. Wheeler, Ryan A. Szeto, Maximillian G. Marin, Richard E. Green, Mariana Sacrini Ayres Ferraz, Priscilla D. Negraes, Beth Shapiro, Christopher Vollmers, Cleber A. Trujillo, Angela N. Brooks, Katerina Semendeferi, Isaac A. Chaim, Edward S. Rice, Allen Wang, Alexandre Hiroaki Kihara, Justin Buchanan, Stephen E. P. Smith, Alik Huseynov, Nathan K. Schaefer, Fernando S. Borges, Assael A. Madrigal, Ashley Byrne, Gene W. Yeo, Alysson R. Muotri
Publikováno v:
Science
Science (New York, N.Y.), vol 371, iss 6530
Science (New York, N.Y.), vol 371, iss 6530
INTRODUCTION: Current views of human evolution, as supported by the fossil record, indicate that many hominin lineage branches arose, but only one survived to the present. Neanderthals and Denisovans, two of these extinct lineages, are our closest ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01306014f12efe117692ba788d2f694e
https://europepmc.org/articles/PMC8006534/
https://europepmc.org/articles/PMC8006534/
Autor:
Juan Wang, Hang Yao, Ines Cerf, Alysson R. Muotri, Helen Zhao, Wei Wu, Priscilla D. Negraes, Gabriel G. Haddad
Publikováno v:
Stem Cell Research, Vol 49, Iss, Pp 102065-(2020)
Prenatal opioids exposure can lead to both neonatal abstinence syndrome in newborns and neurological deficits later in life. Although opioids have been well studied in general, the cellular and molecular mechanisms by which opioids affect human fetal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e62b404e88674cdb64af97f5ead8877
http://www.sciencedirect.com/science/article/pii/S1873506120303664
http://www.sciencedirect.com/science/article/pii/S1873506120303664