Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Priscilla A Furth"'
Autor:
Hyeon Hwa Kim, Hye Kyung Lee, Lothar Hennighausen, Priscilla A. Furth, Heungsup Sung, Jin Won Huh
Publikováno v:
Vaccine: X, Vol 20, Iss , Pp 100565- (2024)
The widespread administration of an additional dose of the SARS-CoV-2 vaccine has been promoted across adult populations, demonstrating a robust immune response against COVID-19. Longitudinal studies provide crucial data on the durability of immune r
Externí odkaz:
https://doaj.org/article/176f010e6b804221b7174459c8b0aafd
Autor:
Marina Carla Cabrera, Estifanos eTilahun, Rebecca eNakles, Edgar eDiaz-Cruz, Aline eCharabaty, Simeng eSuy, Patrick eJackson, Lisa eLey, Rebecca eSlack, Reena eJha, Sean P Collins, Nadim eHaddad, Bhaskar V.S. Kallakury, Timm eSchroeder, Michael J Pishvaian, Priscilla A Furth
Publikováno v:
Frontiers in Oncology, Vol 4 (2014)
Pancreatic ductal adenocarcinoma (PDAC) is characterized by an extensive fibrotic reaction or desmoplasia and complex involvement of the surrounding tumor microenvironment. Pancreatic stellate cells are a key mediator of the pancreatic matrix and the
Externí odkaz:
https://doaj.org/article/593e1d96623e4cb3991919e7eac5a61f
Autor:
Markus Hoffmann, Lina-Liv Willruth, Alexander Dietrich, Hye Kyung Lee, Ludwig Knabl, Nico Trummer, Jan Baumbach, Priscilla A. Furth, Lothar Hennighausen, Markus List
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Bulk RNA sequencing (RNA-seq) of blood is typically used for gene expression analysis in biomedical research but is still rarely used in clinical practice. In this study, we propose that RNA-seq should be considered a diagnostic tool, as it
Externí odkaz:
https://doaj.org/article/8467cfc803f64d2c807e7f55678a08f9
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109177- (2024)
Summary: The COVID-19 pandemic, driven by the SARS-CoV-2 virus and its variants, highlights the important role of understanding host-viral molecular interactions influencing infection outcomes. Alternative splicing post-infection can impact both host
Externí odkaz:
https://doaj.org/article/c3f4ce4a05f347ecbc34f2444deb112c
Autor:
Sahar J. Alothman, Keunsoo Kang, Xuefeng Liu, Ewa Krawczyk, Redha I. Azhar, Rong Hu, David Goerlitz, Bhaskar V. Kallakury, Priscilla A. Furth
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Biology and transcriptomes of non-cancerous human mammary epithelial cells at risk for breast cancer development were explored following primary isolation utilizing conditional reprogramming cell technology from mastectomy tissue ipsilateral
Externí odkaz:
https://doaj.org/article/cd859bc9623041dba2c5112bad9c5e9f
Autor:
Hye Kyung Lee, Ludwig Knabl, Manuel Wieser, Anna Mur, August Zabernigg, Jana Schumacher, Sebastian Kapferer, Norbert Kaiser, Priscilla A. Furth, Lothar Hennighausen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Fast-spreading variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) energize the COVID-19 pandemic. While viral infections elicit a conserved immune response, it is not known whether SARS-CoV-2 variants, which display enh
Externí odkaz:
https://doaj.org/article/336b46306a6a40c2a489ade98377420e
Autor:
Ludwig Knabl, Hye Kyung Lee, Manuel Wieser, Anna Mur, August Zabernigg, Simon Rauch, Matthias Bock, Jana Schumacher, Norbert Kaiser, Priscilla A. Furth, Lothar Hennighausen
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-10 (2022)
Knabl and Lee et al. use RNA sequencing to assess the impact of vaccination with BNT162b2 on the peripheral innate immune response of a small cohort of COVID-19 patients infected with the SARS-CoV-2 Beta variant. They show an increased JAK-STAT-media
Externí odkaz:
https://doaj.org/article/54e9c6af31fe4f418213e9106e27ea0b
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105369- (2022)
Summary: Omicron is currently the dominant SARS-CoV-2 variant and several sublineages have emerged. Questions remain about the impact of previous SARS-CoV-2 exposure on cross-variant immune responses elicited by the SARS-CoV-2 Omicron sublineage BA.2
Externí odkaz:
https://doaj.org/article/fa50563a8ea7401f96369b559f0fe623
Autor:
Danyal Daneshdoust, Mingjue Luo, Zaibo Li, Xiaokui Mo, Sahar Alothman, Bhaskar Kallakury, Richard Schlegel, Junran Zhang, Deliang Guo, Priscilla A. Furth, Xuefeng Liu, Jenny Li
Publikováno v:
Cells, Vol 12, Iss 19, p 2388 (2023)
Preclinical in vitro models play an important role in studying cancer cell biology and facilitating translational research, especially in the identification of drug targets and drug discovery studies. This is particularly relevant in breast cancer, w
Externí odkaz:
https://doaj.org/article/47684bde3c824ba0915d04da340bc0b9
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Although exercise is widely recommended for survivors of cancer, readily implementable approaches for evaluating exercise tolerance enabling exercise prescriptions at appropriate levels of cardiovascular exertion are not always available. We
Externí odkaz:
https://doaj.org/article/3860f1421a514de3b9853458832a7fc0