Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Priscila Longhin, Bosquesi"'
Autor:
Leonardo Fleury Orlandini, Maria Vitória do Nascimento Antonio, Claiver Renato Espreafico Jr, Priscila Longhin Bosquesi, Omero Benedito Poli-Neto, Jurandyr Moreira de Andrade, Francisco José Cândido dos Reis, Daniel Guimarães Tiezzi
Publikováno v:
JCO Global Oncology, Vol , Iss 7, Pp 81-88 (2021)
PURPOSEBreast cancer screening is not recommended for young women (< 40 years old); therefore, those diagnosed are more likely to have advanced and metastatic disease, reducing treatment outcomes. This study aimed to investigate breast cancer epidemi
Externí odkaz:
https://doaj.org/article/0e4add5a7e594de18d1ac3a5a9b839b6
Autor:
Carlos Henrique Lima Imperador, Cauê Benito Scarim, Priscila Longhin Bosquesi, Juliana Romano Lopes, Augusto Cardinalli Neto, Jeanine Giarolla, Elizabeth Igne Ferreira, Jean Leandro dos Santos, Chung Man Chin
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 609 (2022)
Chagas disease (CD) is a neglected protozoan infection caused by Trypanosoma cruzi, which affects about 7 million people worldwide. There are two available drugs in therapeutics, however, they lack effectiveness for the chronic stage—characterized
Externí odkaz:
https://doaj.org/article/3e2a2c2f77d947ffabb67d94d7d02cf7
Autor:
Leandro Augusto Rosseto, Maria Elisa Lopes Pires, Aylime Castanho Bolognesi Melchior, Priscila Longhin Bosquesi, Aline Renata Pavan, Sisi Marcondes, Man Chin Chung, Jean Leandro dos Santos
Publikováno v:
Molecules, Vol 20, Iss 10, Pp 18185-18200 (2015)
Thrombosis is the main outcome of many cardiovascular diseases. Current treatments to prevent thrombotic events involve the long-term use of antiplatelet drugs. However, this therapy has several limitations, thereby justifying the development of new
Externí odkaz:
https://doaj.org/article/a2db657dc6bb4d2f83d64b2875ca34d9
Autor:
Isabela Campeti, Cuoghi, Mariana Furlani, da Silva Soares, Gustavo Motta Cabello, Dos Santos, Francisco José Candido, Dos-Reis, Omero Benedicto, Poli-Neto, Jurandyr Moreira, de Andrade, Priscila Longhin, Bosquesi, Leonardo Fleury, Orlandini, Daniel Guimarães, Tiezzi
Publikováno v:
Journal of Global Health. 12
Mammographic screening has been used to reduce breast cancer mortality worldwide and remains the main modality for the early detection of this disease. Women from low- and middle-income countries still lack access to periodic mammograms and efficient
Autor:
Rafael Consolin Chelucci, Luiz Antônio Dutra, Maria Elisa Lopes Pires, Thais Regina Ferreira de Melo, Priscila Longhin Bosquesi, Man Chin Chung, Jean Leandro dos Santos
Publikováno v:
Molecules, Vol 19, Iss 2, Pp 2089-2099 (2014)
Nonsteroidal anti-inflammatory drugs (NSAIDs) 1–5 containing an N-acyl hydrazone subunit were prepared and their antiplatelet and antithrombotic activities assessed in vitro and in vivo. Compounds 1–5 inhibited the platelet aggregation induced by
Externí odkaz:
https://doaj.org/article/e94f9980cf8b4224ad5a42ffb4507e84
Autor:
Mayna Brito Fukushima, Bruna Galdorfini Chiari, Priscila Longhin Bosquesi, Chung Man Chin, Vera Lucia Borges Isaac
Publikováno v:
ULAKES JOURNAL OF MEDICINE. 2
Métodos de modificação molecular, especialmente a latenciação, têm se apresentado promissores na obtenção de fármacos mais eficientes no que diz respeito à farmacocinética. O desenvolvimento de pró-fármacos permite aumentar a atividade d
Autor:
Paulo Renato Yamasaki, Ednir Oliveira Vizioli, Jean Leandro dos Santos, Priscila Longhin Bosquesi, Pedro Malatesta, Man Chin Chung
Publikováno v:
Pharmaceuticals, Vol 5, Iss 10, Pp 1128-1146 (2012)
Amino acids are well known to be an important class of compounds for the maintenance of body homeostasis and their deficit, even for the polar neuroactive aminoacids, can be controlled by supplementation. However, for the amino acid taurine (2-aminoe
Externí odkaz:
https://doaj.org/article/986393efe011458cba833922faeda7d0
Autor:
Jean Leandro dos Santos, Man Chin Chung, Ednir Oliveira Vizioli, Priscila Longhin Bosquesi, Thais Regina Ferreira Melo
Publikováno v:
Pharmaceuticals, Vol 4, Iss 11, Pp 1450-1474 (2011)
The design of new drugs with better physiochemical properties, adequate absorption, distribution, metabolism, and excretion, effective pharmacologic potency and lacking toxicity remains is a challenge. Inflammation is the initial trigger of several d
Externí odkaz:
https://doaj.org/article/fc25e607f1b840f0b91704722282a9f8
Autor:
Man Chin Chung, Lídia Moreira Lima, Jean Leandro dos Santos, Eliana Aparecida Varanda, Priscila Longhin Bosquesi
Publikováno v:
Molecules, Vol 16, Iss 4, Pp 2982-2989 (2011)
The compounds 1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl nitrate (C1), (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl nitrate (C2), 3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzyl nitrate (C3), 4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-hydroxy-
Externí odkaz:
https://doaj.org/article/9b8c6d16678d4cffb289edfbcb6e9cd2
Autor:
Man Chin Chung, Elizabeth Igne Ferreira, Jean Leandro Santos, Jeanine Giarolla, Daniela Gonçales Rando, Adélia Emília Almeida, Priscila Longhin Bosquesi, Renato Farina Menegon, Lorena Blau
Publikováno v:
Molecules, Vol 13, Iss 3, Pp 616-677 (2008)
Recently, World Health Organization (WHO) and Medicins San Frontieres (MSF) proposed a classification of diseases as global, neglected and extremely neglected. Global diseases, such as cancer, cardiovascular and mental (CNS) diseases represent the ta
Externí odkaz:
https://doaj.org/article/636b91f683504073bca22e1c5ff53396