Výsledky vyhledávání - "Priscila G. Reis"

Akademický článek

Antileishmanial activity of fullerol and its liposomal formulation in experimental models of visceral leishmaniasis

Autor: Guilherme S. Ramos, Virgínia M.R. Vallejos, Marina S. Ladeira, Priscila G. Reis, Daniel M. Souza, Yuri A. Machado, Luiz O. Ladeira, Maurício B.V. Pinheiro, Maria N. Melo, Ricardo T. Fujiwara, Frédéric Frézard

Publikováno v: Biomedicine & Pharmacotherapy, Vol 134, Iss , Pp 111120- (2021)

Visceral leishmaniasis (VL) is a systemic parasitic disease that leads to high rates of morbidity and mortality in humans worldwide. There is a great need to develop new drugs and novel strategies to make chemotherapy for this disease more efficaciou

Externí odkaz: https://doaj.org/article/934ec4ddd6844fca882df840ada97b8d

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Akademický článek

Improved Antileishmanial Activity of Dppz through Complexation with Antimony(III) and Bismuth(III): Investigation of the Role of the Metal

Autor: Cynthia Demicheli, Frédéric Frézard, Maria N. Melo, Priscila G. Reis, Nivaldo L. Speziali, Nelson G. Fernandes, Rubens L. Monte-Neto, Edgar H. Lizarazo-Jaimes

Publikováno v: Molecules, Vol 17, Iss 11, Pp 12622-12635 (2012)

Two novel trivalent antimony(III) and bismuth(III) complexes with the nitrogen-donor heterocyclic ligand dipyrido[3,2-a:2',3'-c]phenazine (dppz) were synthesized and characterized as [Sb(dppz)Cl3]∙H2O∙CH3OH and [Bi(dppz)Cl3]. The crystal structur

Externí odkaz: https://doaj.org/article/03dd2065c539440e887df3ba76e60025

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Antileishmanial activity of fullerol and its liposomal formulation in experimental models of visceral leishmaniasis

Autor: Yuri Machado, Marina Ladeira, Maurício B.V. Pinheiro, Virgínia M.R. Vallejos, Priscila G. Reis, Frédéric Frézard, Ricardo Toshio Fujiwara, Guilherme Santos Ramos, Daniel Menezes Souza, Maria Norma Melo, Luiz Orlando Ladeira

Publikováno v: Biomedicine & Pharmacotherapy, Vol 134, Iss, Pp 111120-(2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38efc4e18aa6589c5b1d7a7adfae6b93
https://pubmed.ncbi.nlm.nih.gov/33341671

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Biophysical and Pharmacological Characterization of Energy-Dependent Efflux of Sb in Laboratory-Selected Resistant Strains of Leishmania (Viannia) Subgenus

Autor: Priscila G. Reis, Maria Norma Melo, Rubens L. Monte-Neto, Frédéric Frézard

Publikováno v: Frontiers in Cell and Developmental Biology

The growing resistance of leishmaniasis to first-line drugs like antimonials in some regions limits the control of this parasitic disease. The precise mechanisms involved in Leishmania antimony resistance are still subject to debate. The reduction of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5b82ee07c2342521fb1f7044066877
https://doi.org/10.3389/fcell.2017.00024

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Antimony transport mechanisms in resistant leishmania parasites

Autor: Priscila G. Reis, Rubens L. Monte-Neto, Frédéric Frézard

Publikováno v: Biophysical Reviews. 6:119-132

Antimonial compounds have been used for more than a century in the treatment of the parasitic disease leishmaniasis. Although pentavalent antimonials are still first-line drugs in several developing countries, this class of drugs is no longer recomme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e4592c58fa8ce53988d39a887e44f14
https://doi.org/10.1007/s12551-013-0134-y

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Hepatotoxicity of Pentavalent Antimonial Drug: Possible Role of Residual Sb(III) and Protective Effect of Ascorbic Acid

Autor: Pascal Salaün, Paula Peixoto Campos, Priscila G. Reis, Kelly Cristina Kato, Ana Rabello, Neila Márcia Silva-Barcellos, José Dias Corrêa-Junior, Cynthia Demicheli, Eliane de Morais-Teixeira, Frédéric Frézard

Publikováno v: Antimicrobial Agents and Chemotherapy. 58:481-488

Pentavalent antimonial drugs such as meglumine antimoniate (Glucantime [Glu; Sanofi-Aventis, São Paulo, Brazil]) produce severe side effects, including cardiotoxicity and hepatotoxicity, during the treatment of leishmaniasis. We evaluated the role o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64489ef1f5b4ec025a47535ed8383fe
https://doi.org/10.1128/aac.01499-13

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Synthesis and characterization of bismuth(III) and antimony(V) porphyrins: high antileishmanial activity against antimony-resistant parasite

Autor: Maria Norma Melo, Frédéric Frézard, Gilson DeFreitas-Silva, Ynara Marina Idemori, Cynthia Demicheli, Marcela Luísa Gomes, Priscila G. Reis

Publikováno v: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 20(5)

Two bismuth(III) porphyrins-5,10,15,20-tetrakis(phenyl)porphyrinatobismuth(III) nitrate, [Bi(III)(TPP)]NO3, and the unprecedent 5,10,15,20-tetrakis(4-carbomethoxyphenyl)porphyrinatobismuth(III) nitrate, [Bi(III)(T4CMPP)]NO3, and two unprecedented ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793cfbb04fffb1b2b1d14fdfae240103
https://pubmed.ncbi.nlm.nih.gov/25929728

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Complexes of different nitrogen donor heterocyclic ligands with SbCl3 and PhSbCl2 as potential antileishmanial agents against Sb(III)-sensitive and -resistant parasites

Autor: Frédéric Frézard, Priscila G. Reis, Edgar H. Lizarazo-Jaimes, Cynthia Demicheli, Filipe M. Bezerra, Rubens L. Monte-Neto, Bernardo L. Rodrigues, Maria Norma Melo

Publikováno v: Journal of inorganic biochemistry. 132

Novel trivalent antimony complexes with the nitrogen donor heterocyclic ligand 2,2′-bipyridine (bipy), 1,10-phenanthroline (phen) or dipyrido[3,2-d:2′,3′-f]quinoxaline (dpq) have been synthesized by the reaction with SbCl 3 or PhSbCl 2 . The cr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16146e8f99a5b11d3d4a0a6fdd2653f6
https://pubmed.ncbi.nlm.nih.gov/24412095

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Improved antileishmanial activity of Dppz through complexation with antimony(III) and bismuth(III): investigation of the role of the metal

Autor: Priscila G. Reis, Rubens L. Monte-Neto, Edgar H. Lizarazo-Jaimes, Maria Norma Melo, Nelson G. Fernandes, Cynthia Demicheli, Frédéric Frézard, Nivaldo L. Speziali

Publikováno v: Molecules
Molecules; Volume 17; Issue 11; Pages: 12622-12635
Molecules, Vol 17, Iss 11, Pp 12622-12635 (2012)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9118667aa21664a188070f5a3e0cfc19
https://pubmed.ncbi.nlm.nih.gov/23099618

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Reduced cardiovascular alterations of tartar emetic administered in long-circulating liposomes in rats

Autor: Priscila G. Reis, Frédéric Frézard, Neila Márcia Silva-Barcellos, Náira Rezende Maciel, Alessandra Teixeira Vidal, Andrea Grabe-Guimarães, Kelly Cristina Kato, Homero Nogueira Guimarães

Publikováno v: Repositório Institucional da UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP

Trivalent antimonial drugs, including tartar emetic (TA), are known to induce important cardiotoxicity observed by electrocardiographic abnormalities. Liposome encapsulation was found to reduce the overall acute toxicity of TA. The present work inves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a335142ac0d0cd2b16788c6820c5b4
https://pubmed.ncbi.nlm.nih.gov/20837118

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