Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Priscila Darakjian"'
Autor:
Justin Q. Anderson, Priscila Darakjian, Robert Hitzemann, Denesa R. Lockwood, Tamara J. Phillips, Angela R. Ozburn
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
The collaborative cross (CC) founder strains include five classical inbred laboratory strains [129S1/SvlmJ (S129), A/J (AJ), C57BL/6J (B6), NOD/ShiLtJ (NOD), and NZO/HILtJ (NZO)] and three wild-derived strains [CAST/EiJ (CAST), PWK/PhJ (PWK), and WSB
Externí odkaz:
https://doaj.org/article/78e62170347c4b1fb8ce0129ee185874
Autor:
Alexandre M. Colville, Ovidiu D. Iancu, Denesa R. Lockwood, Priscila Darakjian, Shannon K. McWeeney, Robert Searles, Christina Zheng, Robert Hitzemann
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
The high genetic complexity found in heterogeneous stock (HS-CC) mice, together with selective breeding, can be used to detect new pathways and mechanisms associated with ethanol preference and excessive ethanol consumption. We predicted that these p
Externí odkaz:
https://doaj.org/article/b180ed117aa142ceb89470e8d4e5a7e3
Autor:
Ovidiu D Iancu, Denesa Oberbeck, Priscila Darakjian, Sunita Kawane, Jason Erk, Shannon McWeeney, Robert Hitzemann
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58951 (2013)
We performed short-term bi-directional selective breeding for haloperidol-induced catalepsy, starting from three mouse populations of increasingly complex genetic structure: an F2 intercross, a heterogeneous stock (HS) formed by crossing four inbred
Externí odkaz:
https://doaj.org/article/9c27291aaa58414f944bbf61d8f8d3cc
Autor:
Ted G Laderas, Nicole A R Walter, Michael Mooney, Kristina Vartanian, Priscila Darakjian, Kari Buck, Christina A Harrington, John Belknap, Robert Hitzemann, Shannon K McWeeney
Publikováno v:
Frontiers in Neuroscience, Vol 5 (2011)
Background: With the advent of the GeneChip Exon Arrays, it is now possible to extract "exon-level" expression estimates, allowing for detection of alternative splicing events, one of the primary mechanisms of transcript diversity. In the context of
Externí odkaz:
https://doaj.org/article/f2daf5516ea44ba7b743b3dd17324118
Autor:
Daniel Bottomly, Nicole A R Walter, Jessica Ezzell Hunter, Priscila Darakjian, Sunita Kawane, Kari J Buck, Robert P Searles, Michael Mooney, Shannon K McWeeney, Robert Hitzemann
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17820 (2011)
C57BL/6J (B6) and DBA/2J (D2) are two of the most commonly used inbred mouse strains in neuroscience research. However, the only currently available mouse genome is based entirely on the B6 strain sequence. Subsequently, oligonucleotide microarray pr
Externí odkaz:
https://doaj.org/article/8d702ee811a94b6ca1ea0133f06ae691
Publikováno v:
GeroScience
Obesity, the cessation of ovarian steroids with menopause, and age are risk factors for mood disorders, dementia, and Alzheimer’s disease (AD). However, immediate hormone therapy (HT) after menopause may have beneficial effects in different brain r
Autor:
Kari J. Buck, Denesa R. Lockwood, Stephanie Edmunds, Robert Hitzemann, Priscila Darakjian, Karen Shepherdson, Laura B. Kozell
Publikováno v:
Alcoholism, Clinical and Experimental Research
Background Genetic factors significantly affect alcohol consumption and vulnerability to withdrawal. Furthermore, some genetic models showing predisposition to severe withdrawal are also predisposed to low ethanol (EtOH) consumption and vice versa, e
Effect of chronic ethanol consumption in rhesus macaques on the nucleus accumbens core transcriptome
Autor:
Karina G. Ray, Suzanne S. Fei, Priscila Darakjian, Denesa R. Lockwood, Christina Zheng, Nicole A.R. Walter, Rita Cervera-Juanes, Verginia Cuzon-Carlson, Robert Hitzemann, Donald F. Conrad, Robert P. Searles, Kathleen A. Grant
Publikováno v:
Addiction biology
The nucleus accumbens core (NAcc) has been repeatedly demonstrated to be a key component of the circuitry associated with excessive ethanol consumption. Previous studies have illustrated that in a nonhuman primate (NHP) model of chronic ethanol consu
Autor:
Robert Hitzemann, Christina Zheng, Megan K. Mulligan, Shannon K. McWeeney, Brien P. Riley, Robert P. Searles, Priscila Darakjian, Ovidiu D. Iancu, Sean P. Farris, Michael F. Miles, Robert W. Williams, Nicole A.R. Walter, R. Dayne Mayfield, Denesa Oberbeck, Kathleen A. Grant, Marcelo F. Lopez, James B. Daunais, Alexander Colville
Publikováno v:
Alcohol. 72:19-31
This review summarizes the proceedings of a symposium presented at the "Alcoholism and Stress: A Framework for Future Treatment Strategies" conference held in Volterra, Italy on May 9-12, 2017. Psychiatric diseases, including alcohol-use disorders (A
Autor:
Denesa R. Lockwood, Robert P. Searles, Robert Hitzemann, Tamara J. Phillips, Priscila Darakjian
Publikováno v:
Genomics
Of the more than 100 studies that have examined relationships between excessive ethanol consumption and the brain transcriptome, few rodent studies have examined chronic consumption. Heterogeneous stock collaborative cross mice freely consumed ethano