Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Priscila, Pereira Sena"'
Autor:
Priscila Pereira Sena, Jonasz Jeremiasz Weber, Sercan Bayezit, Rafael Saup, Rana Dilara Incebacak Eltemur, Xiaoling Li, Ana Velic, Jaqueline Jung, Boris Macek, Huu Phuc Nguyen, Olaf Riess, Thorsten Schmidt
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Lysine residues are one of the main sites for posttranslational modifications of proteins, and lysine ubiquitination of the Machado-Joseph disease protein ataxin-3 is implicated in its cellular function and polyglutamine expansion-dependent toxicity.
Externí odkaz:
https://doaj.org/article/ab398446675b41ffa6299a6e3522a89b
Autor:
Anna S. Sowa, Taissia G. Popova, Tina Harmuth, Jonasz J. Weber, Priscila Pereira Sena, Jana Schmidt, Jeannette Hübener-Schmid, Thorsten Schmidt
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-10 (2021)
Abstract Spinocerebellar ataxia type 3 (SCA3) is a rare neurodegenerative disorder resulting from an aberrant expansion of a polyglutamine stretch in the ataxin-3 protein and subsequent neuronal death. The underlying intracellular signaling pathways
Externí odkaz:
https://doaj.org/article/dd3a817d8b094125ab52f24cb6be995d
Autor:
Jonasz Jeremiasz Weber, Stefanie Cari Anger, Priscila Pereira Sena, Rana Dilara Incebacak Eltemur, Chrisovalantou Huridou, Florian Fath, Caspar Gross, Nicolas Casadei, Olaf Riess, Huu Phuc Nguyen
Publikováno v:
A: Pathogenic mechanisms.
Autor:
Jonasz Jeremiasz Weber, Stefanie Cari Anger, Priscila Pereira Sena, Rana Dilara Incebacak Eltemur, Chrisovalantou Huridou, Florian Fath, Caspar Gross, Nicolas Casadei, Olaf Riess, Huu Phuc Nguyen
Publikováno v:
Cellular and Molecular Life Sciences. 79
Spinocerebellar ataxia type 17 (SCA17) is a neurodegenerative disease caused by a polyglutamine-encoding trinucleotide repeat expansion in the gene of transcription factor TATA box-binding protein (TBP). While its underlying pathomechanism is elusive
Autor:
Vanessa Mendonça, Priscila Pereira Sena, Anna Claudia Evangelista dos Santos, Cibele Rodrigues Bonvicino, Patricia Ashton-Prolla, Sidnei Epelman, Sima Esther Ferman, Pablo Lapunzina, Julián Nevado, Nathalia Grigorovski, Clarissa Mattosinho, Hector Seuànez, Fernando Regla Vargas
Publikováno v:
Experimental eye research. 224
Retinoblastoma is a rare childhood tumor caused by the inactivation of both copies of the RB1 gene. Early diagnosis and identification of heritable RB1 mutation carriers can improve the disease outcome and management via genetic counseling. We used t
Autor:
Mahkameh Abeditashi, Katherine J. Robinson, Jacob Helm, Thorsten Schmidt, Olaf Riess, Jonasz J. Weber, Zinah Wassouf, Stefan Hauser, Ludger Schöls, Jana Schmidt, Maxinne Watchon, Angela S. Laird, Priscila Pereira Sena, Jeannette Hübener-Schmid
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 118(47), e2025810118 (2021). doi:10.1073/pnas.2025810118
Aberrant O-GlcNAcylation, a protein posttranslational modification defined by the O-linked attachment of the monosaccharide N-acetylglucosamine (O-GlcNAc), has been implicated in neurodegenerative diseases. However, although many neuronal proteins ar
Autor:
Priscila, Pereira Sena, Jonasz J, Weber, Maxinne, Watchon, Katherine J, Robinson, Zinah, Wassouf, Stefan, Hauser, Jacob, Helm, Mahkameh, Abeditashi, Jana, Schmidt, Jeannette, Hübener-Schmid, Ludger, Schöls, Angela S, Laird, Olaf, Riess, Thorsten, Schmidt
Publikováno v:
Proc Natl Acad Sci U S A
Aberrant O-GlcNAcylation, a protein posttranslational modification defined by the O-linked attachment of the monosaccharide N-acetylglucosamine (O-GlcNAc), has been implicated in neurodegenerative diseases. However, although many neuronal proteins ar