Výsledky vyhledávání - "Prisca Mbikou"

Akademický článek

Acute Decompensated Heart Failure and the Kidney: Physiological, Histological and Transcriptomic Responses to Development and Recovery

Autor: Miriam T. Rademaker, Anna P. Pilbrow, Leigh J. Ellmers, Suetonia C. Palmer, Trent Davidson, Prisca Mbikou, Nicola J. A. Scott, Elizabeth Permina, Christopher J. Charles, Zoltán H. Endre, A. Mark Richards

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 18 (2021)

BACKGROUND Acute decompensated heart failure (ADHF) is associated with deterioration in renal function—an important risk factor for poor outcomes. Whether ADHF results in permanent kidney damage/dysfunction is unknown. METHODS AND RESULTS We invest

Externí odkaz: https://doaj.org/article/930d9cc955984a1a8054ae333227dfbe

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Acute Decompensated Heart Failure and the Kidney: Physiological, Histological and Transcriptomic Responses to Development and Recovery

Autor: Zoltan H. Endre, Christopher J. Charles, Prisca Mbikou, A. Mark Richards, Leigh J. Ellmers, Elizabeth Permina, Miriam T. Rademaker, Suetonia C. Palmer, Anna P. Pilbrow, Trent Davidson, Nicola J. A. Scott

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 18 (2021)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084077aba95f06402ae71d0132a991c8
https://doi.org/10.1161/jaha.121.021312

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Transcriptomic responses associated with kidney injury and repair in acute decompensated heart failure

Autor: Zoltan H. Endre, Miriam T. Rademaker, Leigh J. Ellmers, Suetonia C. Palmer, Nicola J. A. Scott, Arthur Mark Richards, T Davidson, Christopher J. Charles, Anna P. Pilbrow, Prisca Mbikou

Publikováno v: European Heart Journal. 41

Background The discovery of new markers for acute kidney injury (AKI) in acute decompensated heart failure (ADHF) has been hampered by an incomplete understanding of the pathological processes underlying AKI in ADHF. Purpose In a sheep model of ADHF,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7350030d3f88485697d1b4b05cb99619
https://doi.org/10.1093/ehjci/ehaa946.0875

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Cardiovascular effects of DWORF (dwarf open reading frame) peptide in normal and ischaemia/reperfused isolated rat hearts

Autor: Mark Richards, Chris J. Pemberton, Miriam T. Rademaker, Prisca Mbikou, Christopher J. Charles

Publikováno v: Peptides. 124:170192

The novel peptide dwarf open reading frame (DWORF), highly conserved across species and expressed almost exclusively in cardiac ventricular muscle, may play a role in cardiac physiology and pathophysiology. The effect of direct administration of DWOR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a6010ce4f17e491c8f324a90ca076f
https://doi.org/10.1016/j.peptides.2019.170192

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Effect of length oscillations on airway smooth muscle reactivity and cross-bridge cycling

Autor: Prisca Mbikou, Ahmed M. Al-Jumaily, Prachi R. Redey

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 303:L286-L294

Excessive airway narrowing due to airway smooth muscle (ASM) hyperconstriction is a major symptom in many respiratory diseases. In vitro imposition of length oscillations similar to those produced by tidal breathing on contracted ASM have shown to re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634cc4b7b8be6d863058032f4aa0dcf5
https://doi.org/10.1152/ajplung.00100.2012

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Theoretical and Experimental Investigation of Calcium-Contraction Coupling in Airway Smooth Muscle

Autor: Milan Brumen, Prisca Mbikou, Aleš Fajmut, Etienne Roux

Publikováno v: Cell Biochemistry and Biophysics. 46:233-252

We investigated theoretically and experimentally the Ca2+-contraction coupling in rat tracheal smooth muscle. [Ca2+]i, isometric contraction and myosin light chain (MLC) phosphorylation were measured in response to 1 mM carbachol. Theoretical modelin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc50fbdc2ad24ee1b7abacab95c89f9
https://doi.org/10.1385/cbb:46:3:233

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Combined Effect of Isoproterenol and Mechanical Oscillation on the Contractile Response of Mice Airway Smooth Muscle

Autor: Prisca Mbikou, Miguel Jo-Avila, Ahmed M. Al-Jumaily, Luis Sobrevia

Publikováno v: Volume 2: Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology.

An asthmatic attack is instigated by hyperconstriction of airway smooth muscle (ASM). This can be relieved with bronchodilator medication such as Isoproterenol (ISO). This paper hypothesizes that mechanical oscillations may improve drugs therapy when

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::404ae47d22808df6ca53dcc7a61dd30c
https://doi.org/10.1115/imece2011-63163

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Contribution of Rho kinase to the early phase of the calcium-contraction coupling in airway smooth muscle

Autor: Prisca, Mbikou, Ales, Fajmut, Milan, Brumen, Etienne, Roux

Publikováno v: Experimental physiology. 96(2)

We investigated theoretically and experimentally the role of Rho kinase (RhoK) in Ca(2+)-contraction coupling in rat airways. Isometric contraction was measured on tracheal, extrapulmonary and intrapulmonary bronchial rings. Intracellular [Ca(2+)] wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4299f188a2f86525ee892a25b1ed42fd
https://pubmed.ncbi.nlm.nih.gov/20870731

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