Zobrazeno 1 - 10
of 261
pro vyhledávání: '"Prion protein (PrP)"'
Publikováno v:
Advanced Science, Vol 11, Iss 38, Pp n/a-n/a (2024)
Abstract Endometriosis, a chronic inflammatory disease, significantly impairs the quality of life of women in their reproductive years; however, its pathogenesis remains poorly understood. The accumulation of retrograde menstruation and recurrent ble
Externí odkaz:
https://doaj.org/article/a8de1040935f47d48354f1a5ae485283
Autor:
Patricia Soto, Davis T. Thalhuber, Frank Luceri, Jamie Janos, Mason R. Borgman, Noah M. Greenwood, Sofia Acosta, Hunter Stoffel
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2024)
The Prion protein is the molecular hallmark of the incurable prion diseases affecting mammals, including humans. The protein-only hypothesis states that the misfolding, accumulation, and deposition of the Prion protein play a critical role in toxicit
Externí odkaz:
https://doaj.org/article/ecd404949b99405b86c0e805d6c1e5a4
Akademický článek
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Autor:
Ignazio Cali, Laura Cracco, Dario Saracino, Rossana Occhipinti, Cinzia Coppola, Brian Stephen Appleby, Gianfranco Puoti
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
The insertion of additional 168 base pair containing seven octapeptide repeats in the prion protein (PrP) gene region spanning residues 51–91 is associated with inherited prion disease. In 2008, we reported the clinical features of a novel de novo
Externí odkaz:
https://doaj.org/article/be3cf2568b694a1bbe5248cfdbf84111
Autor:
Santra Brenna, Hermann C. Altmeppen, Behnam Mohammadi, Björn Rissiek, Florence Schlink, Peter Ludewig, Christoph Krisp, Hartmut Schlüter, Antonio Virgilio Failla, Carola Schneider, Markus Glatzel, Berta Puig, Tim Magnus
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Extracellular vesicles (EVs) are important means of intercellular communication and a potent tool for regenerative therapy. In ischaemic stroke, transient blockage of a brain artery leads to a lack of glucose and oxygen in the affected brain tissue,
Externí odkaz:
https://doaj.org/article/8b3f873bf1d34191be2c0a2b5d004183
Autor:
Shannon L. Risacher, Martin R. Farlow, Daniel R. Bateman, Francine Epperson, Eileen F. Tallman, Rose Richardson, Jill R. Murrell, Frederick W. Unverzagt, Liana G. Apostolova, Jose M. Bonnin, Bernardino Ghetti, Andrew J. Saykin
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-17 (2018)
Abstract This study aimed to determine the pattern of [18F]flortaucipir uptake in individuals affected by Gerstmann-Sträussler-Scheinker disease (GSS) associated with the PRNP F198S mutation. The aims were to: 1) determine the pattern of [18F]florta
Externí odkaz:
https://doaj.org/article/5c0a7d3492ac45e8976cd091f820b920
Akademický článek
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Akademický článek
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Autor:
Yoshiki Takamatsu, Makoto Hashimoto, Ryoko Wada, Gilbert Ho, Eliezer Masliah, Takato Takenouchi, Masaaki Waragai, Shuei Sugama
Publikováno v:
Prion
Creutzfeldt-Jackob disease (CJD), the most common human prion disorder, is frequently accompanied by ageing-associated neurodegenerative conditions, such as Alzheimer’s disease and Parkinson’s disease. Although cross-seeding of amyloidogenic prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f89b6cb6a988ba8783a81822e275202
https://doi.org/10.1080/19336896.2020.1761514
https://doi.org/10.1080/19336896.2020.1761514
Publikováno v:
Annals of Indian Academy of Neurology, Vol 12, Iss 1, Pp 48-51 (2009)
Prion diseases are rare, progressive and fatal neurodegenerative diseases characterized by long incubation period and short clinical course. We present a rare case of Heidenhain variant of Creutzfeldt-Jakob disease, occurring in a 55-year-old lady pr
Externí odkaz:
https://doaj.org/article/747d5855b4b74fdf92ce6665a2181159