Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Prince Kumar Lat"'
Autor:
Sarah E. Arthur, Aixiang Jiang, Bruno M. Grande, Miguel Alcaide, Razvan Cojocaru, Christopher K. Rushton, Anja Mottok, Laura K. Hilton, Prince Kumar Lat, Eric Y. Zhao, Luka Culibrk, Daisuke Ennishi, Selin Jessa, Lauren Chong, Nicole Thomas, Prasath Pararajalingam, Barbara Meissner, Merrill Boyle, Jordan Davidson, Kevin R. Bushell, Daniel Lai, Pedro Farinha, Graham W. Slack, Gregg B. Morin, Sohrab Shah, Dipankar Sen, Steven J. M. Jones, Andrew J. Mungall, Randy D. Gascoyne, Timothy E. Audas, Peter Unrau, Marco A. Marra, Joseph M. Connors, Christian Steidl, David W. Scott, Ryan D. Morin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The driver mutations for the two main molecular subgroups of diffuse large B-cell lymphoma (DLBCL) are poorly defined. Here, an integrative genomics analysis identifies 3′ UTR NFKBIZ mutations within the activated B-cell DLBCL subgroup and small FC
Externí odkaz:
https://doaj.org/article/3f5730acbfb542c08d8c3ac5e60f9653
Autor:
Prince Kumar Lat, Dipankar Sen
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198418 (2018)
Massive expansion of a DNA hexanucleotide sequence repeat (C2G4) within the human C9orf72 gene has been linked to a number of neurodegenerative diseases. In sodium or potassium salt solutions, single-stranded d(C2G4)n DNAs fold to form G-quadruplexes
Externí odkaz:
https://doaj.org/article/8d7b7ad4216c4fa499aabaf6ae4b54f2
Publikováno v:
Angewandte Chemie International Edition. 60:8722-8727
We report a new DNA nanostructure, an extended 1-dimensional composite built for the first time out of structurally robust yet conveniently disassembled DNA triple helices, interspersed with short stretches of G-quadruplexes. These "TQ Hybrid" 1-dime
Publikováno v:
Nucleic Acids Research
To enable the optimal, biocompatible and non-destructive application of the highly useful copper (Cu+)-mediated alkyne-azide ‘click’ cycloaddition in water, we have isolated and characterized a 79-nucleotide DNA enzyme or DNAzyme, ‘CLICK-17’,
Autor:
Dev N Kumar, Dipankar Sen, Esther M. Verheyen, Prince Kumar Lat, Kenneth Kin Lam Wong, Kun Liu
Publikováno v:
Nucleic Acids Research
Guanine-rich, single-stranded DNAs and RNAs that fold to G-quadruplexes (GQs) are able to complex tightly with heme and display strongly enhanced peroxidase activity. Phenolic compounds are particularly good substrates for these oxidative DNAzymes an
Autor:
Jordan Davidson, Christopher Rushton, Graham W. Slack, David W. Scott, Daisuke Ennishi, Randy D. Gascoyne, Gregg B. Morin, Joseph M. Connors, Nicole Thomas, Luka Culibrk, Prasath Pararajalingam, Lauren Chong, Ryan D. Morin, Andrew J. Mungall, Steven J. M. Jones, Eric Y. Zhao, Sarah E. Arthur, Christian Steidl, Laura K. Hilton, Aixiang Jiang, Merrill Boyle, Dipankar Sen, Timothy E. Audas, Kevin Bushell, Anja Mottok, Miguel Alcaide, Bruno M. Grande, Barbara Meissner, Selin Jessa, Marco A. Marra, Peter J. Unrau, Pedro Farinha, Sohrab P. Shah, Daniel Lai, Prince Kumar Lat, Razvan Cojocaru
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Nature Communications
Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer originating from mature B-cells. Prognosis is strongly associated with molecular subgroup, although the driver mutations that distinguish the two main subgroups remain poorly defined. Thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02eeaac7c291321bd3340f900e0484be
http://summit.sfu.ca/item/18251
http://summit.sfu.ca/item/18251
Autor:
Selin Jessa, Marco A. Marra, David W. Scott, Christopher Rushton, Ryan D. Morin, Daniel Lai, Kevin Bushell, Jordan Davidson, Sarah E. Arthur, Andrew J. Mungall, Joseph M. Connors, Daisuke Ennishi, Prince Kumar Lat, Anja Mottok, Randy D. Gascoyne, Barbara Meissner, Sohrab P. Shah, Merrill Boyle, Dipankar Sen, Pedro Farinha, Lauren Chong, Prasath Pararajalingam, Steven J. M. Jones, Christian Steidl, Aixiang Jiang, Graham W. Slack, Miguel Alcaide, Bruno M. Grande
Publikováno v:
bioRxiv
Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer originating from mature B-cells. Many known driver mutations are over-represented in one of its two molecular subgroups, knowledge of which has aided in the development of therapeutics tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0f6b82e67eb1990a17066c1da77e57
https://doi.org/10.1101/225870
https://doi.org/10.1101/225870