Identifying general reaction conditions by bandit optimization.

Autor: Wang JY; Department of Chemistry, Princeton University, Princeton, NJ, USA.; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA., Stevens JM; Chemical Process Development, Bristol Myers Squibb, Summit, NJ, USA., Kariofillis SK; Department of Chemistry, Princeton University, Princeton, NJ, USA.; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA.; Department of Chemistry, Columbia University, New York, NY, USA., Tom MJ; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA., Golden DL; Chemical Process Development, Bristol Myers Squibb, Summit, NJ, USA., Li J; Chemical Process Development, Bristol Myers Squibb, New Brunswick, NJ, USA., Tabora JE; Chemical Process Development, Bristol Myers Squibb, New Brunswick, NJ, USA., Parasram M; Department of Chemistry, Princeton University, Princeton, NJ, USA.; Department of Chemistry, New York University, New York, NY, USA., Shields BJ; Department of Chemistry, Princeton University, Princeton, NJ, USA.; Molecular Structure and Design, Bristol Myers Squibb, Cambridge, MA, USA., Primer DN; Chemical Process Development, Bristol Myers Squibb, Summit, NJ, USA.; Loxo Oncology at Lilly, Louisville, CO, USA., Hao B; Janssen Research and Development, Spring House, PA, USA., Del Valle D; Chemical Process Development, Bristol Myers Squibb, New Brunswick, NJ, USA., DiSomma S; Chemical Process Development, Bristol Myers Squibb, New Brunswick, NJ, USA., Furman A; Chemical Process Development, Bristol Myers Squibb, New Brunswick, NJ, USA., Zipp GG; Discovery Synthesis, Bristol Myers Squibb, Princeton, NJ, USA., Melnikov S; Spectrix Analytical Services, North Haven, CT, USA., Paulson J; Chemical Process Development, Bristol Myers Squibb, New Brunswick, NJ, USA., Doyle AG; Department of Chemistry, Princeton University, Princeton, NJ, USA. agdoyle@chem.ucla.edu.; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA. agdoyle@chem.ucla.edu.

Publikováno v: Nature [Nature] 2024 Feb; Vol. 626 (8001), pp. 1025-1033. Date of Electronic Publication: 2024 Feb 28.

Enabling the Cross-Coupling of Tertiary Organoboron Nucleophiles through Radical-Mediated Alkyl Transfer.

Autor: Primer DN; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania , Philadelphia, Pennsylvania 19104-6323, United States., Molander GA; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania , Philadelphia, Pennsylvania 19104-6323, United States.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2017 Jul 26; Vol. 139 (29), pp. 9847-9850. Date of Electronic Publication: 2017 Jul 18.

Preparation of visible-light-activated metal complexes and their use in photoredox/nickel dual catalysis.

Autor: Kelly CB; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Patel NR; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Primer DN; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Jouffroy M; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Tellis JC; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Molander GA; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Publikováno v: Nature protocols [Nat Protoc] 2017 Mar; Vol. 12 (3), pp. 472-492. Date of Electronic Publication: 2017 Feb 02.

Base-Free Photoredox/Nickel Dual-Catalytic Cross-Coupling of Ammonium Alkylsilicates.

Autor: Jouffroy M; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania , Philadelphia, Pennsylvania 19104-6323, United States., Primer DN; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania , Philadelphia, Pennsylvania 19104-6323, United States., Molander GA; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania , Philadelphia, Pennsylvania 19104-6323, United States.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2016 Jan 20; Vol. 138 (2), pp. 475-8. Date of Electronic Publication: 2015 Dec 24.

Photoredox Cross-Coupling: Ir/Ni Dual Catalysis for the Synthesis of Benzylic Ethers.

Autor: Karakaya I; ‡Department of Chemistry, Faculty of Sciences and Letters, Osmaniye Korkut Ata University, 80000 Osmaniye, Turkey., Primer DN; †Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States., Molander GA; †Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States.

Publikováno v: Organic letters [Org Lett] 2015 Jul 02; Vol. 17 (13), pp. 3294-7. Date of Electronic Publication: 2015 Jun 16.