Zobrazeno 1 - 10
of 910
pro vyhledávání: '"Primary transcript"'
Publikováno v:
RNA. 27:1140-1147
Human metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a nuclear long noncoding RNA (lncRNA) that is highly overexpressed in many cancer tissues and plays important roles in tumor progression and metastasis. The MALAT1 primary trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c54856f33387dc2ee32549809e57f90
https://doi.org/10.1261/rna.078810.121
https://doi.org/10.1261/rna.078810.121
Publikováno v:
Journal of Integrative Agriculture, Vol 12, Iss 9, Pp 1522-1529 (2013)
The importance of microRNA (miRNA) at the post-transcriptional regulation level has recently been recognized in both animals and plants. In recent years, many studies focused on miRNA target identification and functional analysis. However, little is
Externí odkaz:
https://doaj.org/article/f6ae3f339af34170993482b703cba5fc
Publikováno v:
Plant Cell, Tissue and Organ Culture (PCTOC). 144:345-357
Lpu-miR171 participates in lily somatic embryogenesis by regulating SCARECROW-LIKE 6 transcription factors. However, the regulatory mechanism of lpu-miR171 remains unclear. In this study, we identified the primary transcript of lpu-miR171a and analyz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22046954787ab8c0b2f100c0245039fc
https://doi.org/10.1007/s11240-020-01957-5
https://doi.org/10.1007/s11240-020-01957-5
Autor:
Jeesoo Kim, S. Chan Baek, Suman Wang, V. Narry Kim, Jihye Yang, Siyuan Shen, Fudong Li, Yunyu Shi, Jong-Seo Kim, Kijun Kim, S. Chul Kwon, Harim Jang
Publikováno v:
Nucleic Acids Research
The microprocessor complex cleaves the primary transcript of microRNA (pri-miRNA) to initiate miRNA maturation. Microprocessor is known to consist of RNase III DROSHA and dsRNA-binding DGCR8. Here, we identify Enhancer of Rudimentary Homolog (ERH) as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f5c5fcde36d0a1eaed902ff3fa9d74
https://doi.org/10.1093/nar/gkaa827
https://doi.org/10.1093/nar/gkaa827
Autor:
Anna Teresiak, Katarzyna Lamperska, Magda Kopczyńska, Renata Bliźniak, Tomasz Kolenda, Joanna Sobocińska, Kacper Guglas
Publikováno v:
Rep Pract Oncol Radiother
miR-18a is a member of primary transcript called miR-17-92a (C13orf25 or MIR17HG) which also contains five other miRNAs: miR-17, miR-19a, miR-20a, miR-19b and miR-92a. This cluster as a whole shows specific characteristics, where miR-18a seems to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83911ed4d272b63e3bacd5de21c347d
https://doi.org/10.1016/j.rpor.2020.07.006
https://doi.org/10.1016/j.rpor.2020.07.006
Autor:
Ronald Swanstrom, Trinity Zang, Daniel R. Kuritzkes, Athe M. N. Tsibris, Phillip J. Tomezsko, Anthony T. Papenfuss, Ann Emery, Matthew D. Edwards, Tammy C. T. Lan, Paromita Gupta, Harish Swaminathan, Paul D. Bieniasz, Sitara Persad, Lachlan McIntosh, Vincent Corbin, Silvi Rouskin, Margalit Glasgow
Publikováno v:
Nature
Human immunodeficiency virus 1 (HIV-1) is a retrovirus with a ten-kilobase single-stranded RNA genome. HIV-1 must express all of its gene products from a single primary transcript, which undergoes alternative splicing to produce diverse protein produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada02574b201f96085c349314b09362f
http://europepmc.org/articles/PMC7310298
http://europepmc.org/articles/PMC7310298
Autor:
Jessica L. Childs-Disney, Hafeez S. Haniff, Haruo Aikawa, Xiaohui Liu, Alexander Adibekian, Anton Shuster, Matthew D. Disney
Publikováno v:
J Am Chem Soc
Many RNAs are processed into biologically active transcripts, the aberrant expression of which can contribute to disease phenotypes. For example, the primary microRNA-17-92 (pri-miR-17-92) cluster contains six microRNAs (miRNAs) that collectively act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773fa4116811378942589b11b1c18ee8
https://doi.org/10.1021/jacs.9b13159
https://doi.org/10.1021/jacs.9b13159
Autor:
Lin Jinrong, Xinke Xu, Zhao Lingfeng, Hongyao Yuan, Jin Bilian, Chen Cheng, Wei Chen, Junping Pan, Junliang Li, Fangcheng Li, Li Yang
Publikováno v:
Journal of Cellular Physiology. 235:7344-7355
Glioblastoma (GBM) is the most malignant primary brain tumor in adults. Due to its invasive nature, it cannot be thoroughly eliminated. WD repeat domain 12 (WDR12) processes the 32S precursor rRNA but cannot affect the synthesis of the 45S/47S primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745d9d0cc6b5ebab4b0db51e910eb5b5
https://doi.org/10.1002/jcp.29635
https://doi.org/10.1002/jcp.29635
Publikováno v:
Curr Genet
In Saccharomyces cerevisiae, the mitoribosomal RNA of the minor subunit,15S rRNA, is transcribed as a bicistronic transcript along with tRNA(W). 5’ and 3’ sequences flanking the mature transcript must be removed by cleavage at the respective junc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f31ea36022e8047268e9f593e3708f
https://doi.org/10.1007/s00294-020-01064-0
https://doi.org/10.1007/s00294-020-01064-0
Autor:
Xu Liu, Rui Cheng, Chuan Zhou, Mengyun Wang, Yingmei Wang, Yong Zhang, Xiaoman Zheng, Fusheng Quan, Jun Liu
Publikováno v:
Biology of Reproduction. 102:999-1010
Alternative splicing (AS) of mRNA precursors allows the synthesis of multiple mRNAs from a single primary transcript, significantly expanding the information content and regulatory possibilities of higher eukaryotic genomes. During mammalian developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82ca826e37f7dc0c892e0b054beb669
https://doi.org/10.1093/biolre/ioaa004
https://doi.org/10.1093/biolre/ioaa004