Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Primary human macrophages"'
Autor:
Sinem Gunalp, Derya Goksu Helvaci, Aysenur Oner, Ahmet Bursalı, Alessandra Conforte, Hüseyin Güner, Gökhan Karakülah, Eva Szegezdi, Duygu Sag
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundTNF-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can either induce cell death or activate survival pathways after binding to death receptors (DRs) DR4 or DR5. TRAIL is investigated as a therapeutic agent
Externí odkaz:
https://doaj.org/article/4de8f8e86e3642108304756b87a6437c
Autor:
Joana Wilton, Filipa Lopes de Mendonça, Isabel Pereira-Castro, Michael Tellier, Takayuki Nojima, Angela M. Costa, Jaime Freitas, Shona Murphy, Maria Jose Oliveira, Nicholas J. Proudfoot, Alexandra Moreira
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMacrophages are essential cells of the immune system that alter their inflammatory profile depending on their microenvironment. Alternative polyadenylation in the 3’UTR (3’UTR-APA) and intronic polyadenylation (IPA) are mechanisms tha
Externí odkaz:
https://doaj.org/article/03c0414266d441a4894af70fb55f5004
Autor:
Gül Kilinç, Kimberley V. Walburg, Kees L. M. C. Franken, Merel L. Valkenburg, Alexandra Aubry, Mariëlle C. Haks, Anno Saris, Tom H. M. Ottenhoff
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The Mycobacterium avium (Mav) complex accounts for more than 80% of all pulmonary diseases caused by non-tuberculous mycobacteria (NTM) infections, which have an alarming increase in prevalence and vary in different regions, currently reaching 0.3–
Externí odkaz:
https://doaj.org/article/da295c0ae99748708f62ed7e974666b5
Autor:
Cassandra L. R. van Doorn, Gina K. Schouten, Suzanne van Veen, Kimberley V. Walburg, Jeroen J. Esselink, Matthias T. Heemskerk, Frank Vrieling, Tom H. M. Ottenhoff
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Global increases in the prevalence of antimicrobial resistance highlight the urgent need for novel strategies to combat infectious diseases. Recent studies suggest that host metabolic pathways play a key role in host control of intracellular bacteria
Externí odkaz:
https://doaj.org/article/01155c0bee704eccac2e991f18f0b985
Autor:
Carina C. dos Santos, Kimberley V. Walburg, Suzanne van Veen, Louis G. Wilson, Carlos E. M. Trufen, Ivan P. Nascimento, Tom H. M. Ottenhoff, Luciana C. C. Leite, Mariëlle C. Haks
Publikováno v:
Vaccines, Vol 10, Iss 6, p 831 (2022)
Tuberculosis (TB) is one of the top 10 leading causes of death worldwide. The recombinant BCG strain expressing the genetically detoxified A subunit of the thermolabile toxin from Escherichia coli (LTAK63) adjuvant (rBCG-LTAK63) has previously been s
Externí odkaz:
https://doaj.org/article/3b4aebfc765a4714867b961abb674a36
Akademický článek
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Publikováno v:
Journal of Pain Research, Vol Volume 12, Pp 69-81 (2018)
Perla Abigail Alvarado-Vázquez,1 Rachel L Grosick,2 Carolina Moracho-Vilrriales,2 Eileen Ward,2 Tiffaney Threatt,2 Edgar Alfonso Romero-Sandoval3 1Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden; 2D
Externí odkaz:
https://doaj.org/article/2ae2bce66b65493499bddfe99b50d72b
Akademický článek
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Autor:
Doorn, C.L.R. van
Publikováno v:
None
In this thesis we describe our work regarding the identification of novel biomarkers, host targets and candidate pharmacological compounds for the development of therapies against various intracellular bacterial infections, focusing primarily on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::004493a00acef4ecf0b58fed5bbcbf9f
https://hdl.handle.net/1887/3486320
https://hdl.handle.net/1887/3486320
