Zobrazeno 1 - 10
of 3 240
pro vyhledávání: '"Primary Cilium"'
Autor:
Iveta Putnová, Barbora Moldovan Putnová, Pavel Hurník, Jan Štembírek, Marcela Buchtová, Petra Kolísková
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Squamous cell carcinoma (SCC) of the head and neck originates from the mucosal lining of the upper aerodigestive tract, including the lip, tongue, nasopharynx, oropharynx, larynx and hypopharynx. In this review, we summarise what is currently known a
Externí odkaz:
https://doaj.org/article/34020c2b57254742812945fbef839f1a
Autor:
Jia Tian, Julianne C. Mallinger, Ping Shi, Dahao Ling, Loic P. Deleyrolle, Min Lin, Habibeh Khoshbouei, Matthew R. Sarkisian
Publikováno v:
Translational Oncology, Vol 45, Iss , Pp 101956- (2024)
Tumor Treating Fields (TTFields) extend the survival of glioblastoma (GBM) patients by interfering with a broad range of tumor cellular processes. Among these, TTFields disrupt primary cilia stability on GBM cells. Here we asked if concomitant treatm
Externí odkaz:
https://doaj.org/article/57ef9904b530417fbe1d5d0a9438b3c5
Autor:
María Paz Hernández-Cáceres, Daniela Pinto-Nuñez, Patricia Rivera, Paulina Burgos, Francisco Díaz-Castro, Alfredo Criollo, Maria Jose Yañez, Eugenia Morselli
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 2, Pp 264-271 (2024)
The brain is, after the adipose tissue, the organ with the greatest amount of lipids and diversity in their composition in the human body. In neurons, lipids are involved in signaling pathways controlling autophagy, a lysosome-dependent catabolic pro
Externí odkaz:
https://doaj.org/article/e1663c66758146ab8112d833c18a8d55
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/31a3f509af3e4080af1c932f2717d821
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
The cilium, a pivotal organelle crucial for cell signaling and proper cell function, relies on meticulous macromolecular transport from the cytoplasm for its formation and maintenance. While the intraflagellar transport (IFT) pathway has traditionall
Externí odkaz:
https://doaj.org/article/3123d609d8a542908da595d800807866
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/b01236b97bd0401bab9efc29bce9e0ec
Autor:
Frontiers Production Office
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/1e387653e4794f19a3d78b44fea4d97d
Publikováno v:
Frontiers in Nephrology, Vol 3 (2024)
Ciliopathies are a group of rare genetic disorders caused by defects to the structure or function of the primary cilium. They often affect multiple organs, leading to brain malformations, congenital heart defects, and anomalies of the retina or skele
Externí odkaz:
https://doaj.org/article/59fa3abad73f40be8822e82583be5d8d
Autor:
Stefaan W. Verbruggen, Joanne Nolan, Michael P. Duffy, Oliver M.T. Pearce, Christopher R. Jacobs, Martin M. Knight
Publikováno v:
Advanced Science, Vol 11, Iss 2, Pp n/a-n/a (2024)
Abstract Bone metastases are a common cause of suffering in breast and prostate cancer patients, however, the interaction between bone cells and cancer cells is poorly understood. Using a series of co‐culture, conditioned media, human cancer sphero
Externí odkaz:
https://doaj.org/article/76aa04d7a7fa4f45a303ab43a8ff8637
Publikováno v:
eLife, Vol 12 (2023)
The Hedgehog (Hh) family of secreted proteins governs embryonic development and adult tissue homeostasis through the Gli family of transcription factors. Gli is thought to be activated at the tip of primary cilium, but the underlying mechanism has re
Externí odkaz:
https://doaj.org/article/3e88d51026194aef89a44b61da39ed62