Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Primali V. Navaratne"'
Autor:
Ion Ghiviriga, Kavindri D. Ranasinghe, Primali V. Navaratne, Jenny L. Wilkerson, Jasmine S. Felix, Lance R. McMahon, Evgeniya Semenova, Adrian E. Roitberg, Alexander J. Grenning
Publikováno v:
ChemMedChem
Phytocannabinoids (and synthetic analogs thereof) are gaining significant attention as promising leads in modern medicine. Considering this, new directions for the design of phytocannabinoid-inspired molecules is of immediate interest. In this regard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1075bdb7cc691965086f9c59171e8fe4
https://doi.org/10.1002/cmdc.202000025
https://doi.org/10.1002/cmdc.202000025
Publikováno v:
Organic & Biomolecular Chemistry. 15:69-75
A simple platform for carbocycle synthesis by Knoevenagel adduct deconjugative alkylation/Heck reaction is described. Deconjugative alkylation of Knoevenagels adducts is two-fold synthetically enabling because C-C bond formation is (1) operationally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7955ff96620472b0dc8a0283bd6f09b3
https://doi.org/10.1039/c6ob02250b
https://doi.org/10.1039/c6ob02250b
Autor:
Adrian E. Roitberg, Lance R. McMahon, Evgeniya Semenova, Jenny L. Wilkerson, Ion Ghivirga, Kavindri D. Ranasinghe, Alex Grenning, Primali V. Navaratne
Phytocannabinoids, molecules isolated from cannabis, are gaining attention as promising leads in modern medicine, including pain management. Considering the urgent need for combating the opioid crisis, new directions for the design of cannabinoid-ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df4e8269d30a2259a09fca908290d2e6
https://doi.org/10.26434/chemrxiv.10251035.v1
https://doi.org/10.26434/chemrxiv.10251035.v1
Autor:
Primali V. Navaratne, Alexander J. Grenning, Kavindri D. Ranasinghe, Lance R. McMahon, Jenny L. Wilkerson, Evgeniya Semenova, Ion Ghiviriga, Jasmine S. Felix, Adrian E. Roitberg
Publikováno v:
ChemMedChem. 15:727-727
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d2952d0fc70a9860a8872c8eacc4fd3
https://doi.org/10.1002/cmdc.202000140
https://doi.org/10.1002/cmdc.202000140
Publikováno v:
Organic letters. 20(15)
A modular and practical route to versatile cyano-1,3-dienes by a sequence involving deconjugative alkylation and "Tsuji-Saegusa-Ito oxidation" is reported. In this letter, the versatility of the products is also explored, including a route to benzoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dea4ebe7575fb42bc4803ac422e8149
https://pubmed.ncbi.nlm.nih.gov/30009612
https://pubmed.ncbi.nlm.nih.gov/30009612
Publikováno v:
ChemInform. 47
Knoevenagel adducts derived from readily available acetoxyacetone and malonic acid derivatives served as trimethylenemethane surrogates for formal 1,3-difunctionalization through a sequence of selective γ-deprotonation/α-alkylation and palladium(0)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34fbd24a5359f8d21625d5d673715385
https://doi.org/10.1002/chin.201619048
https://doi.org/10.1002/chin.201619048
Publikováno v:
Angewandte Chemie (International ed. in English). 55(1)
Knoevenagel adducts derived from readily available acetoxyacetone and malonic acid derivatives served as trimethylenemethane surrogates for formal 1,3-difunctionalization through a sequence of selective γ-deprotonation/α-alkylation and palladium(0)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278d9771f44b79f4c7c29e40a25835c5
https://pubmed.ncbi.nlm.nih.gov/26490159
https://pubmed.ncbi.nlm.nih.gov/26490159