Zobrazeno 1 - 10
of 2 929
pro vyhledávání: '"Priller A"'
Autor:
Wieser, Alexander, Lachner, Johannes, Martschini, Martin, Zok, Dorian, Priller, Alfred, Steier, Peter, Golser, Robin
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Volume 538, May 2023, Pages 36-40
The detection of low abundances of $^{135}$Cs in environmental samples is of significant interest in different fields of environmental sciences, especially in combination with its shorter-lived sister isotope $^{137}$Cs. The method of Ion-Laser Inter
Externí odkaz:
http://arxiv.org/abs/2410.21079
The automated generation of diverse and complex training scenarios has been an important ingredient in many complex learning tasks. Especially in real-world application domains, such as autonomous driving, auto-curriculum generation is considered vit
Externí odkaz:
http://arxiv.org/abs/2403.17805
Autor:
Niklas Vockert, Judith Machts, Luca Kleineidam, Aditya Nemali, Enise I. Incesoy, Jose Bernal, Hartmut Schütze, Renat Yakupov, Oliver Peters, Daria Gref, Luisa Sophie Schneider, Lukas Preis, Josef Priller, Eike Jakob Spruth, Slawek Altenstein, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Ayda Rostamzadeh, Wenzel Glanz, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias H. Munk, Annika Spottke, Nina Roy, Michael T. Heneka, Frederic Brosseron, Michael Wagner, Steffen Wolfsgruber, Laura Dobisch, Peter Dechent, Stefan Hetzer, Klaus Scheffler, Peter Zeidman, Yaakov Stern, Björn H. Schott, Frank Jessen, Emrah Düzel, Anne Maass, Gabriel Ziegler, the DELCODE study group
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The cognitive reserve (CR) hypothesis posits that individuals can differ in how their brain function is disrupted by pathology associated with aging and neurodegeneration. Here, we test this hypothesis in the continuum from cognitively norma
Externí odkaz:
https://doaj.org/article/d47f0410fc5e498aa3d4d536cb833fd9
Autor:
Inga Menze, Jose Bernal, Pinar Kaya, Çağla Aki, Malte Pfister, Jonas Geisendörfer, Renat Yakupov, Roberto Duarte Coello, Maria d. C. Valdés-Hernández, Michael T. Heneka, Frederic Brosseron, Matthias C. Schmid, Wenzel Glanz, Enise I. Incesoy, Michaela Butryn, Ayda Rostamzadeh, Dix Meiberth, Oliver Peters, Lukas Preis, Dominik Lammerding, Daria Gref, Josef Priller, Eike J. Spruth, Slawek Altenstein, Andrea Lohse, Stefan Hetzer, Anja Schneider, Klaus Fliessbach, Okka Kimmich, Ina R. Vogt, Jens Wiltfang, Claudia Bartels, Björn H. Schott, Niels Hansen, Peter Dechent, Katharina Buerger, Daniel Janowitz, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias H. Munk, Carolin Sanzenbacher, Petra Hinderer, Klaus Scheffler, Annika Spottke, Nina Roy-Kluth, Falk Lüsebrink, Katja Neumann, Joanna Wardlaw, Frank Jessen, Stefanie Schreiber, Emrah Düzel, Gabriel Ziegler
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Perivascular space (PVS) enlargement in ageing and Alzheimer’s disease (AD) and the drivers of such a structural change in humans require longitudinal investigation. Elucidating the effects of demographic factors, hypertension,
Externí odkaz:
https://doaj.org/article/63eb7743209c40979f7c3e0fd2e5303c
Autor:
Jose Bernal, Inga Menze, Renat Yakupov, Oliver Peters, Julian Hellmann-Regen, Silka Dawn Freiesleben, Josef Priller, Eike Jakob Spruth, Slawek Altenstein, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Björn H. Schott, Frank Jessen, Ayda Rostamzadeh, Wenzel Glanz, Enise I. Incesoy, Katharina Buerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Christoph Laske, Sebastian Sodenkamp, Annika Spottke, Anna Esser, Falk Lüsebrink, Peter Dechent, Stefan Hetzer, Klaus Scheffler, Stefanie Schreiber, Emrah Düzel, Gabriel Ziegler
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background For over three decades, the concomitance of cortical neurodegeneration and white matter hyperintensities (WMH) has sparked discussions about their coupled temporal dynamics. Longitudinal studies supporting this hypothesis nonethel
Externí odkaz:
https://doaj.org/article/2fc8b02963e64d939d0391d39c8e28cb
Autor:
Sunniva M. K. Bøstrand, Luise A. Seeker, Nadine Bestard-Cuche, Nina-Lydia Kazakou, Sarah Jäkel, Boyd Kenkhuis, Neil C. Henderson, Susanne T. de Bot, Willeke M. C. van Roon-Mom, Josef Priller, Anna Williams
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease with a fatal outcome. There is accumulating evidence of a prominent role of glia in the pathology of HD, and we investigated this by conducting single nuclear RNA
Externí odkaz:
https://doaj.org/article/481020d6c0a242d9bbb0b2caef4a4421
Autor:
Martschini Martin, Lachner Johannes, Merchel Silke, Priller Alfred, Steier Peter, Wallner Anton, Wieser Alexander, Golser Robin
Publikováno v:
EPJ Web of Conferences, Vol 232, p 02003 (2020)
The long-lived radioisotope 182Hf (T1/2 = 8.9 Ma) is of high astrophysical interest as its potential abundance in environmental archives would provide insight into recent r-process nucleosynthesis in the vicinity of our solar system. Despite substant
Externí odkaz:
https://doaj.org/article/dd7f2db6cb64421587f1e95826c28cd8
Autor:
Pawel Lisowski, Selene Lickfett, Agnieszka Rybak-Wolf, Carmen Menacho, Stephanie Le, Tancredi Massimo Pentimalli, Sofia Notopoulou, Werner Dykstra, Daniel Oehler, Sandra López-Calcerrada, Barbara Mlody, Maximilian Otto, Haijia Wu, Yasmin Richter, Philipp Roth, Ruchika Anand, Linda A. M. Kulka, David Meierhofer, Petar Glazar, Ivano Legnini, Narasimha Swamy Telugu, Tobias Hahn, Nancy Neuendorf, Duncan C. Miller, Annett Böddrich, Amin Polzin, Ertan Mayatepek, Sebastian Diecke, Heidi Olzscha, Janine Kirstein, Cristina Ugalde, Spyros Petrakis, Sidney Cambridge, Nikolaus Rajewsky, Ralf Kühn, Erich E. Wanker, Josef Priller, Jakob J. Metzger, Alessandro Prigione
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-27 (2024)
Abstract Expansion of the glutamine tract (poly-Q) in the protein huntingtin (HTT) causes the neurodegenerative disorder Huntington’s disease (HD). Emerging evidence suggests that mutant HTT (mHTT) disrupts brain development. To gain mechanistic in
Externí odkaz:
https://doaj.org/article/340c015abcae4c679391b04ea77b6a41
Autor:
Spyridon Siafis, Hui Wu, Nobuyuki Nomura, Johannes Schneider-Thoma, Irene Bighelli, Carolin Lorenz, Joseph E. Dib, Prathap Tharyan, Leonie A. Calver, Geoffrey K. Isbister, Esther W. Y. Chan, Jonathan C. Knott, Celene Y. L. Yap, Célia Mantovani, Marc L. Martel, David Barbic, William G. Honer, Wulf-Peter Hansen, Gisele Huf, Jacob Alexander, Nirmal S. Raveendran, Evandro S. F. Coutinho, Josef Priller, Clive E. Adams, Georgia Salanti, Stefan Leucht
Publikováno v:
Systematic Reviews, Vol 13, Iss 1, Pp 1-11 (2024)
Abstract Background Severe psychomotor agitation and aggression often require immediate pharmacological intervention, but clear evidence-based recommendations for choosing among the multiple options are lacking. To address this gap, we plan a systema
Externí odkaz:
https://doaj.org/article/3b0d75a1b9c946069ec67702c27c2c95
Autor:
Laura de Boni, Amber Wallis, Aurelia Hays Watson, Alejandro Ruiz-Riquelme, Louise-Ann Leyland, Thomas Bourinaris, Naomi Hannaway, Ullrich Wüllner, Oliver Peters, Josef Priller, Björn H Falkenburger, Jens Wiltfang, Mathias Bähr, Inga Zerr, Katharina Bürger, Robert Perneczky, Stefan Teipel, Matthias Löhle, Wiebke Hermann, Björn-Hendrik Schott, Kathrin Brockmann, Annika Spottke, Katrin Haustein, Peter Breuer, Henry Houlden, Rimona S Weil, Tim Bartels
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 7, Pp 1657-1674 (2024)
Abstract Synucleinopathies such as Parkinson’s disease (PD) are defined by the accumulation and aggregation of the α-synuclein protein in neurons, glia and other tissues. We have previously shown that destabilization of α-synuclein tetramers is a
Externí odkaz:
https://doaj.org/article/236805c429ea4d8aa5198401625295ba