Výsledky vyhledávání

Enzymic peroxidation of lipids and oxidative metabolism of chlorpromazine in brain microsomal fraction

Autor: I. A. Eluashvili, Prilipko Ll, V. E. Kagan

Publikováno v: Bulletin of Experimental Biology and Medicine. 86:1321-1324

Enzymic NADPH-dependent systems of lipid peroxidation and chlorpromazine metabolism were shown to be localized in rat and human brain microsomal fractions (BMF). Hydroxy-derivatives of chlorpromazine [7-hydroxychlorpromazine (7-OH)] formed as a resul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::47a25121fdcc9db6b5854b3309165aaf
https://doi.org/10.1007/bf00800447

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Nadph- and organic hydroperoxide-dependent oxidation of adrenalin into adrenochrome in liver and brain microsomes

Autor: Prilipko Ll, Valerian E. Kagan, I. A. Eluashvili, V. A. Pisarev, V. M. Savov

Publikováno v: Bulletin of Experimental Biology and Medicine. 90:1525-1528

It was shown that oxidation of adrenaline to adrenochrome in microsomal membranes of the brain and liver in the presence of NADP . H2 or NAD . H2 is mainly accounted for by the formation of a superoxide anion radical. The formation of adrenochrome fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b71f3fedb98cc927342036bfe49f0ec
https://doi.org/10.1007/bf00834084

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Lipid peroxidation and retinal injury in stress

Autor: S. K. Dobrina, Meerson Fz, I. Ya. Kuliev, Prilipko Ll, Anna A. Shvedova, Yu. P. Kozlov, Valerian E. Kagan

Publikováno v: Bulletin of Experimental Biology and Medicine. 93:408-411

Emotional-painful stress (EPS) regularly leads to generalized activation of lipid peroxidation (LPO), and this is expressed as accumulation of LPO products in various tissues: the brain, heart, muscles, etc. [5, 6]. Activation of LPO has been shown t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::314d8ecbc3925ff944234dbc017b8732
https://doi.org/10.1007/bf00830534

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Effect of chlorpromazine on enzymic oxidation of lipids

Autor: Bogdanova Ed, Prilipko Ll, V. E. Kagan, T. P. Pashinova, I. A. Eluashvili

Publikováno v: Bulletin of Experimental Biology and Medicine. 84:1302-1306

Chlorpromazine was found to inhibit enzymic NADPH-dependent peroxidation of lipids in rat liver microsomes. The inhibitory effect was shown to be due to: 1) the antioxidant action of hydroxy derivatives of chlorpromazine produced in the course of its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4153397c159fa7e40e6ae05534c71a6c
https://doi.org/10.1007/bf00805891

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Role of lipid peroxidation in serotonin receptor injury and onset of epileptiform seizures during hyperoxia

Autor: Valerian E. Kagan, V. M. Savov, Prilipko Ll, R. A. Kopaladze

Publikováno v: Bulletin of Experimental Biology and Medicine. 96:1664-1667

Epileptiform seizures are a characteristic manifestation of the toxic action of oxygen (hyperoxia) on the brain [9, 13]. An essential role in seizure formation can be played by damage to the serotoninergic system of the brain [7]. However, the concre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a33d51cff09609d53dde65fee253153
https://doi.org/10.1007/bf00834297

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Accumulation of gaseous lipid peroxidation products in the expired air in children during hyperbaric oxygenation

Autor: Prilipko Ll, Valerian E. Kagan, V. M. Savov, V. S. Shapot, A. I. Saltanov, O. N. Orlov, E. B. Uvarova

Publikováno v: Bulletin of Experimental Biology and Medicine. 96:1367-1369

logic Practice [in Russian], Leningrad (1976), pp. 17-23. 4. L.A. Sidorenko, in: Problems in the Diagnosis and Treatment of Nonspecific Lung Diseases [in Russian], Alma-Ata (1979), pp. 32-33. 5. L.A. Sidorenko and A. Ya. Afanas'ev, in: Respiratory In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d97b423bbe7386bccf83b900a6850ed3
https://doi.org/10.1007/bf00837913

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