Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Priit Paluoja"'
Autor:
Alvin Meltsov, Merli Saare, Hindrek Teder, Priit Paluoja, Riikka K. Arffman, Terhi Piltonen, Piotr Laudanski, Mirosław Wielgoś, Luca Gianaroli, Mariann Koel, Maire Peters, Andres Salumets, Kaarel Krjutškov, Priit Palta
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Expressional profiling of the endometrium enables the personalised timing of the window of implantation (WOI). This study presents and evaluates a novel analytical pipeline based on a TAC-seq (Targeted Allele Counting by sequencing) method f
Externí odkaz:
https://doaj.org/article/5fb92c738fde4f878dd96a1928826e5a
Autor:
Sanna Vuoristo, Shruti Bhagat, Christel Hydén-Granskog, Masahito Yoshihara, Lisa Gawriyski, Eeva-Mari Jouhilahti, Vipin Ranga, Mahlet Tamirat, Mikko Huhtala, Ida Kirjanov, Sonja Nykänen, Kaarel Krjutškov, Anastassius Damdimopoulos, Jere Weltner, Kosuke Hashimoto, Gaëlle Recher, Sini Ezer, Priit Paluoja, Pauliina Paloviita, Yujiro Takegami, Ai Kanemaru, Karolina Lundin, Tomi T. Airenne, Timo Otonkoski, Juha S. Tapanainen, Hideya Kawaji, Yasuhiro Murakawa, Thomas R. Bürglin, Markku Varjosalo, Mark S. Johnson, Timo Tuuri, Shintaro Katayama, Juha Kere
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104137- (2022)
Summary: Double homeobox 4 (DUX4) is expressed at the early pre-implantation stage in human embryos. Here we show that induced human DUX4 expression substantially alters the chromatin accessibility of non-coding DNA and activates thousands of newly i
Externí odkaz:
https://doaj.org/article/e20d78e8cdab451083fb4b3f94c08b7f
Autor:
Priit Paluoja, Hindrek Teder, Amin Ardeshirdavani, Baran Bayindir, Joris Vermeesch, Andres Salumets, Kaarel Krjutškov, Priit Palta
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 12, p e1009684 (2021)
Non-invasive prenatal testing (NIPT) is a powerful screening method for fetal aneuploidy detection, relying on laboratory and computational analysis of cell-free DNA. Although several published computational NIPT analysis tools are available, no prio
Externí odkaz:
https://doaj.org/article/9502a8a197d9486dbd7940f103034e13
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0209139 (2019)
Non-invasive prenatal testing (NIPT) enables accurate detection of fetal chromosomal trisomies. The majority of publicly available computational methods for sequencing-based NIPT analyses rely on low-coverage whole-genome sequencing (WGS) data and ar
Externí odkaz:
https://doaj.org/article/9a60aa960dc94e5282ec6b0e36113246
Clinically pathogenic chromosomal microdeletions causing genetic disorders such as DiGeorge syndrome are rare genetic aberrations that can cause clinically relevant fetal and childhood developmental deficiencies. Clinical severity of such deficiencie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::064a295e91938bb703fec8dd332e897a
https://doi.org/10.1101/2022.09.20.22280152
https://doi.org/10.1101/2022.09.20.22280152
Autor:
Alvin Meltsov, Merli Saare, Hindrek Teder, Priit Paluoja, Riikka Arffman, Terhi Piltonen, Piotr Laudanski, Mirosław Wielgoś, Luca Gianaroli, Mariann Koel, Maire Peters, Andres Salumets, Priit Palta, Kaarel Krjutškov
STUDY QUESTIONHow accurately can a targeted gene expression sequencing assay estimate endometrial receptivity corresponding to the window of implantation?DESIGNEndometrial biopsies (n=175) from healthy fertile volunteers (n=66), polycystic ovarian sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bdd2f9014d2b3707383d8d87d10924b
https://doi.org/10.1101/2022.06.13.22276318
https://doi.org/10.1101/2022.06.13.22276318
Autor:
Konstantin Ridnõi, Andres Salumets, Kadri Rekker, Tiia Reimand, Priit Paluoja, Neeme Tõnisson, Eva-Liina Ustav, Lauris Kaplinski, Martin Sauk, Priit Palta, Joris Vermeesch, Hindrek Teder, Olga Žilina, Ants Kurg, Kaarel Krjutškov
Publikováno v:
Prenatal Diagnosis. 39:1262-1268
OBJECTIVE The study aimed to validate a whole-genome sequencing-based NIPT laboratory method and our recently developed NIPTmer aneuploidy detection software with the potential to integrate the pipeline into prenatal clinical care in Estonia. METHOD
Autor:
Timo Tuuri, Pauliina Paloviita, Juha S. Tapanainen, Kaarel Krjutškov, Urmo Võsa, Priit Paluoja, Sanna Vuoristo, Christel Hydén-Granskog, Dawit A. Yohannes, Juha Kere
Publikováno v:
Genome Res
Small noncoding RNAs (sRNAs) play important roles during the oocyte-to-embryo transition (OET), when the maternal phenotype is reprogrammed and the embryo genome is gradually activated. The transcriptional program driving early human development has
Autor:
Priit Paluoja, Anne Mari Roost, Ants Kurg, Nathalie Brison, Priit Palta, Kaarel Krjutškov, Lauris Kaplinski, Martin Sauk, Eva-Liina Ustav, Maire Peters, Hindrek Teder, Andres Salumets, Joris Vermeesch, Olga Žilina
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
Non-invasive prenatal testing (NIPT) is a recent and rapidly evolving method for detecting genetic lesions, such as aneuploidies, of a fetus. However, there is a need for faster and cheaper laboratory and analysis methods to make NIPT more widely acc
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0209139 (2019)
PLoS ONE
PLoS ONE
Non-invasive prenatal testing (NIPT) enables accurate detection of fetal chromosomal trisomies. The majority of publicly available computational methods for sequencing-based NIPT analyses rely on low-coverage whole-genome sequencing (WGS) data and ar