Zobrazeno 1 - 10
of 1 764
pro vyhledávání: '"Prigione, A"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Human induced pluripotent stem cells (iPSCs) have great potential in research, but pluripotency testing faces challenges due to non-standardized methods and ambiguous markers. Here, we use long-read nanopore transcriptome sequencing to disco
Externí odkaz:
https://doaj.org/article/e144b945c29e44ca871a16b9e9f95679
Autor:
Adelizzi Alessia, Giri Anastasia, Di Donfrancesco Alessia, Boito Simona, Prigione Alessandro, Bottani Emanuela, Bollati Valentina, Tiranti Valeria, Persico Nicola, Brunetti Dario
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-30 (2024)
Abstract During embryonic and neonatal development, mitochondria have essential effects on metabolic and energetic regulation, shaping cell fate decisions and leading to significant short- and long-term effects on embryonic and offspring health. Ther
Externí odkaz:
https://doaj.org/article/9737c06aedaa46ff8614d874cc9b1f75
Autor:
Pawel Lisowski, Selene Lickfett, Agnieszka Rybak-Wolf, Carmen Menacho, Stephanie Le, Tancredi Massimo Pentimalli, Sofia Notopoulou, Werner Dykstra, Daniel Oehler, Sandra López-Calcerrada, Barbara Mlody, Maximilian Otto, Haijia Wu, Yasmin Richter, Philipp Roth, Ruchika Anand, Linda A. M. Kulka, David Meierhofer, Petar Glazar, Ivano Legnini, Narasimha Swamy Telugu, Tobias Hahn, Nancy Neuendorf, Duncan C. Miller, Annett Böddrich, Amin Polzin, Ertan Mayatepek, Sebastian Diecke, Heidi Olzscha, Janine Kirstein, Cristina Ugalde, Spyros Petrakis, Sidney Cambridge, Nikolaus Rajewsky, Ralf Kühn, Erich E. Wanker, Josef Priller, Jakob J. Metzger, Alessandro Prigione
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-27 (2024)
Abstract Expansion of the glutamine tract (poly-Q) in the protein huntingtin (HTT) causes the neurodegenerative disorder Huntington’s disease (HD). Emerging evidence suggests that mutant HTT (mHTT) disrupts brain development. To gain mechanistic in
Externí odkaz:
https://doaj.org/article/340c015abcae4c679391b04ea77b6a41
Autor:
Kathleen Bastian-Pétrel, Jessica L. Rohmann, Sabine Oertelt-Prigione, Marco Piccininni, Katja Gayraud, Michelle Kelly-Irving, Nathalie Bajos
Publikováno v:
The Lancet Regional Health. Europe, Vol 45, Iss , Pp 101041- (2024)
Summary: Background: Sex and gender inequalities in ischemic heart diseases persist. Although ischemic heart disease is less common in women, they experience worse clinical outcomes and are less likely to receive guideline-recommended treatments. The
Externí odkaz:
https://doaj.org/article/8f7eece63ba448e593eafa38ee00c59b
Autor:
Laura Petersilie, Karl W. Kafitz, Louis A. Neu, Sonja Heiduschka, Stephanie Le, Alessandro Prigione, Christine R. Rose
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103212- (2024)
Summary: Three-dimensional brain organoids from human pluripotent stem cells are a powerful tool for studying human neural networks. Here, we present a protocol for generating cortical brain organoid slices (cBOS) derived from regionalized cortical o
Externí odkaz:
https://doaj.org/article/1b1c2c848704492f8b2e916be127daec
Autor:
Sabine Ludwig, Sabine Jenner, Ralph Berger, Sylvie Tappert, Christine Kurmeyer, Sabine Oertelt-Prigione, Mandy Petzold
Publikováno v:
BMC Medical Education, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Discrimination and sexual harassment are prevalent in higher education institutions and can affect students, faculty members and employees. Herein the aim was to assess the extent of discriminatory experiences and sexual harassmen
Externí odkaz:
https://doaj.org/article/4e434e49fca64c3587a1e31bcbf59ae7
Autor:
A. Poli, A. Zanellati, E. Piano, F. Biagioli, C. Coleine, G. Nicolosi, L. Selbmann, M. Isaia, V. Prigione, G. C. Varese
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Microbial diversity of caves is largely understudied and its possible applications are still unknown. Autochthonous fungi, in particular, may have the potential to biomineralize metals and may be used as promising agents for bioremediation o
Externí odkaz:
https://doaj.org/article/e1e6b9dc7caa4338aee1b31c5d0578f1
Autor:
Jochen Dobner, Thach Nguyen, Mario Gustavo Pavez-Giani, Lukas Cyganek, Felix Distelmaier, Jean Krutmann, Alessandro Prigione, Andrea Rossi
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101231- (2024)
Mitochondrial DNA (mtDNA) analysis is crucial for the diagnosis of mitochondrial disorders, forensic investigations, and basic research. Existing pipelines are complex, expensive, and require specialized personnel. In many cases, including the diagno
Externí odkaz:
https://doaj.org/article/d31d09eb2eb54ccb8689a2489ed1f56a
Autor:
Bastian-Pétrel, Kathleen, Rohmann, Jessica L., Oertelt-Prigione, Sabine, Piccininni, Marco, Gayraud, Katja, Kelly-Irving, Michelle, Bajos, Nathalie
Publikováno v:
In The Lancet Regional Health - Europe October 2024 45
Autor:
Dobner, Jochen, Nguyen, Thach, Pavez-Giani, Mario Gustavo, Cyganek, Lukas, Distelmaier, Felix, Krutmann, Jean, Prigione, Alessandro, Rossi, Andrea
Publikováno v:
In Molecular Therapy - Methods & Clinical Development 13 June 2024 32(2)