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RECOMBINANT HUMAN INTERLEUKIN-1 RECEPTOR ANTAGONIST IN THE TREATMENT OF PATIENTS WITH SEPSIS SYNDROME - RESULTS FROM A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL

Autor: Fisher, Cj, Dhainaut, Jfa, Opal, Sm, Pribble, Jp, Balk, Ra, Slotman, Gj, Iberti, Tj, Rackow, Ec, Shapiro, Mj, Greenman, Rl, Reines, Hd, Shelly, Mp, Thompson, Bw, Labrecque, Jf, Catalano, Ma, Knaus, Wa, Sadoff, Jc, Astiz, M., Carpati, C., Bone, Rc, Freidman, B., Mure, Aj, Brathwaite, C., Shapiro, E., Melhorn, L., Taylor, R., Keegan, M., Obrien, J., Schein, R., Pena, M., Wasserlouf, M., Oropello, J., Benjamin, E., Delguidice, R., Emmanuel, G., Lie, T., Anderson, L., Marshall, J., Demajo, W., Rotstein, O., Foster, D., Abraham, E., Middleton, H., Perry, C., Levy, H., FRY, DE, Simpson, Sq, Crowell, Re, Neidhart, M., Stevens, D., Coffman, T., Narasimham, N., Merrick, Dk, Bergquist, W., Matzel, Ke, Huebler, M., Foulke, Ge, Albertson, Te, Walby, Wf, Allen, Rp, Baughman, R., Hasselgren, Po, Fink, Mp, Favorito, F., Thompson, Bt, Corbin, R., Shellhorse, Gy, Frazier, A., White, S., Garrard, C., Acourt, C., Storer, S., Gervich, Dh, Foshe, D., Brase, R., Bagdahn, A., Cooney, R., Smith, Js, Martin, Lf, Vincent, Jl, Friedman, G., Berlot, G., Fletcher, Jr, Williams, Md, Wright, Tf, Johnson, S., Feild, C., Wolf, K., Macintyre, N., Dubin, Hg, DURKIN, MR, Dubin, Pk, Staubach, Kh, Fein, Am, Schulman, Db, Niederman, Ms, Chalfin, Db, Vanleeuwen, Pam, Boermeester, Ma, Schneider, Aj, Bander, J., Imm, A., Bernard, G., Nelson, L., Stroud, M., Safcsak, K., Cerra, F., Rindal, J., Mann, H., Halpern, N., Silverstein, J., Alicea, M., Sibbald, Wj, Martin, Cm, Rutledge, Fs, Petti, K., Russell, Ja, Kruger, R., Drummond, A., Lange, P., Seifert, T., Durocher, A., Tenaillon, A., Boiteau, R., Lherm, T., Lowry, Sf, Coyle, Sm, Barie, Ps, Demaria, E., Snydman, Dr, Schwaitzberg, Sd, Nasraway, Sa, Grindlinger, J., Summer, W., Deboisblanc, B., Wahl, M., Alestig, K., Grossman, J., Maki, D., Paz, Hl, Weiner, M., Bihari, D., Campbell, D., Bleichner, G., Dahn, Ms, Lange, Mpa, Hall, J., Pohlman, A., Wenzel, Rp, Grosserode, M., Costigan, M., Mileski, W., Weigelt, J., Yeston, N., Irizarry, C., Ross, J., Robbins, J., Nightingale, P., Owen, K., Sandstedt, S., Berg, S., Simon, Gl, Seneff, Mg, Conry, Km, Zimmerman, Jl, Dellinger, Rp, Johnston, R., Allee, P., Grande, Po, Myhre, E., Dhainaut, Jf, Hamy, I., Mira, Jp, Harmon, J., White, J., Mckie, L., Silverman, H., Tuma, P., Bennett, D., Joanna Porter, Laurell, Mh, Jacobs, S., Ash, S., Stiles, Dm, Prior, Mj, Knatterud, G., Terrin, M., Kufera, J., Wilkens, P., Ra, K., Monroe, L., Sprung, C., Hamilton, Cm, Matthay, R., Mccabe, W., Tonascia, J., Wiedeman, H., Wittes, J., Campion, Gv, Croft, Cr, Lustick, R., Lookabaugh, J., Gordon, Gs, Noe, L., Bloedow, D., Smith, Cg, Brannon, D., Kush, R., Ng, D., Moore, E., Bazemore, K., Galvan, M., Wagner, D., Harrell, F., Stablein, D.

Publikováno v: ResearcherID
JAMA, 271(23), 1836-1843. American Medical Association

Objective.-To further define the safety and efficacy of recombinant human interleukin 1 receptor antagonist (rhlL-1ra) in the treatment of sepsis syndrome. Study Design.-Randomized, double-blind, placebo-controlled, multicenter, multinational clinica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::98064b5379a55772548e9a1f5c3df7aa
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1994NP95900027&KeyUID=WOS:A1994NP95900027

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