Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Prexy Shah"'
Autor:
Thomas J. Cremer, Estelle Cormet-Boyaka, Daren L. Knoell, Mikhail A. Gavrilin, Anasuya Sarkar, Susheela Tridandapani, Devyn D. Gillette, Jonathan P. Butchar, Beth Y. Besecker, Mark D. Wewers, Prexy Shah
Publikováno v:
Journal of Biological Chemistry. 288:3691-3695
Burkholderia cenocepacia, the causative agent of cepacia syndrome, primarily affects cystic fibrosis patients, often leading to death. In the lung, epithelial cells serve as the initial barrier to airway infections, yet their responses to B. cenocepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::432f3c8b2dc5969f5a873c16a12ccd89
https://doi.org/10.1074/jbc.c112.430298
https://doi.org/10.1074/jbc.c112.430298
Autor:
David Huehl Ravneberg, Mark D. Wewers, Thomas J. Cremer, Prexy Shah, Larry S. Schlesinger, Susheela Tridandapani, Kavin Fatehchand, Devyn D. Gillette, Heather M. Curry, Mikhail A. Gavrilin, Jonathan P. Butchar
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 4 (2014)
Frontiers in Cellular and Infection Microbiology, Vol 4 (2014)
Background: Human monocyte inflammatory responses differ between virulent and attenuated Francisella infection. Results: A mixed infection model showed that the virulent F. tularensis Schu S4 can attenuate inflammatory cytokine responses to the less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76fb76c3f6e6f9f9b79d26b11472ac77
https://doi.org/10.3389/fcimb.2014.00045
https://doi.org/10.3389/fcimb.2014.00045
Autor:
Jonathan P. Butchar, Steven E. Justiniano, Kavin Fatehchand, Saranya Elavazhagan, Erin Hertlein, Xiaokui Mo, Natarajan Muthusamy, Payal Mehta, Timothy D. Eubank, Susheela Tridandapani, John C. Byrd, Prexy Shah, Julie M. Roda, Clay B. Marsh, Carolyn Cheney
Publikováno v:
The Journal of biological chemistry. 288(37)
Monocytes/macrophages are potent mediators of antitumor antibody therapy, where they engage target cells via Fcγ receptors (FcγR). Binding of these cells to opsonized tumor targets elicits cytokine production, phagocytosis, and antibody-mediated ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda66eb20dfb70859be594c713c639b7
https://pubmed.ncbi.nlm.nih.gov/23902770
https://pubmed.ncbi.nlm.nih.gov/23902770
Autor:
Kavin Fatehchand, Susheela Tridandapani, David Jarjoura, Steven E. Justiniano, Hemal Patel, Prexy Shah, Xiaokui Mo, Huiqing Fang, Jonathan P. Butchar
Fcγ receptor (FcγR) clustering on monocytes/macrophages results in phagocytosis and inflammatory cytokine production, which serve to eliminate antibody-opsonized targets and activate neighboring immune cells. Toll-like receptor 2 (TLR2), which reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f07fd369ace71c5fc48b508ad70f4a5e
https://europepmc.org/articles/PMC3636918/
https://europepmc.org/articles/PMC3636918/
Autor:
Clay B. Marsh, Kara Batte, Jon Wisler, Melissa G. Piper, Michael E. Paulaitis, Timothy D. Eubank, Susheela Tridandapani, Kitty Agarwal, Leni Moldovan, Yijie Wang, Noura Ismail, Duaa Dakhlallah, Prexy Shah
Microvesicles are small membrane-bound particles comprised of exosomes and various-sized extracellular vesicles. These are released by several cell types. Microvesicles have a variety of cellular functions from communication to mediating growth and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae134a01e4b91ca62fcea3357ae29a61
https://europepmc.org/articles/PMC3567345/
https://europepmc.org/articles/PMC3567345/
Autor:
Devyn D. Gillette, Murugesan V. S. Rajaram, Estelle Cormet-Boyaka, Prexy Shah, Rachel L. Marsh, Kavin Fatehchand, Susheela Tridandapani, Thomas J. Cremer, Hemal Patel, Thirumala-Devi Kanneganti, Larry S. Schlesinger, Jonathan P. Butchar, Beth Y. Besecker
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 2 (2012)
Frontiers in Cellular and Infection Microbiology, Vol 2 (2012)
MiR-155 regulates numerous aspects of innate and adaptive immune function. This miR is induced in response to toll-like receptor ligands, cytokines, and microbial infection. We have previously shown that miR-155 is induced in monocytes/macrophages in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae39b932562b5ca152cbb671ed016d47
http://europepmc.org/articles/PMC3417573
http://europepmc.org/articles/PMC3417573
Autor:
Estelle Cormet-Boyaka, Jonathan P. Butchar, Prexy Shah, Thomas J. Cremer, Susheela Tridandapani, Miguel A. Valvano
The environmental bacterium Burkholderia cenocepacia causes opportunistic lung infections in immunocompromised individuals, particularly in patients with cystic fibrosis. Infections in these patients are associated with exacerbated inflammation leadi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85dd148ba700f7118764e76223bcbd4b
https://europepmc.org/articles/PMC3131456/
https://europepmc.org/articles/PMC3131456/
Publikováno v:
Cancer Research. 74:4530-4530
Chronic lymphocytic leukemia (CLL) is a B-cell malignancy influenced by oncogenic mutations and the factors of the microenvironment such as BCR signaling that promote B-cell survival and proliferation. BCR signaling cascade activates multiple downstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69588bd1f325d17188625cd60ddd2b42
https://doi.org/10.1158/1538-7445.am2014-4530
https://doi.org/10.1158/1538-7445.am2014-4530
Autor:
Saranya Elavazhagan, Prexy Shah, Kavin Fatehchand, Hemal Patel, Carolyn Cheney, Natarajan Muthusamy, John Vasilakos, Maura-Ann Matthews, Gregory Dietsch, Robert Hershberg, John Byrd, Susheela Tridandapani, Jonathan Butchar
Publikováno v:
The Journal of Immunology. 192:203.40-203.40
Monoclonal antibody therapy has been used to treat cancer since 1997, but there is a continued need to improve its effectiveness. We have previously shown that the TLR7/8 dual agonist R-848 could modulate monocyte FcγR expression and function, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f09fbc241f6bac3a79e576eee49c86e
https://doi.org/10.4049/jimmunol.192.supp.203.40
https://doi.org/10.4049/jimmunol.192.supp.203.40
Autor:
Devyn Gillette, Prexy Shah, Thomas Cremer, Mikhail Gavrilin, Beth Besecker, Anasuya Sarkar, Daren Knoell, Estelle Cormet-Boyaka, Mark Wewers, Jonathan Butchar, Susheela Tridandapani
Publikováno v:
The Journal of Immunology. 190:56.15-56.15
Burkholderia cenocepacia is the causative agent of the fatal lung disease, Cepacia syndrome. Epithelial cells are the first cells challenged in airway infections, yet, their pro-inflammatory response to B. cenocepacia remains under investigated. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6ad3e61616ee79abf7248ae84390980
https://doi.org/10.4049/jimmunol.190.supp.56.15
https://doi.org/10.4049/jimmunol.190.supp.56.15