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Synthesis, radiolabeling and first biological characterization of 18F-labeled xanthine derivatives for PET imaging of Eph receptors

Autor: Pretze, M., Neuber, C., Kinski, E., Belter, B., Köckerling, M., Caflisch, A., Steinbach, J., Pietzsch, J., Mamat, C.

Publikováno v: Organic & Biomolecular Chemistry 18(2020)16, 3104-3116

Eph receptor tyrosine kinases, particulary EphA2 and EphB4, represent promising candidates for molecular imaging due to their essential role in cancer progression and therapy resistance. Xanthine derivatives were identified to be potent Eph receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::87a4b1622f3f8df6cff2a5f46f18894c
https://www.hzdr.de/publications/Publ-30738-1

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18F-Labeling and Radiopharmacological Evaluation of Novel Purinedione Multi-Eph Inhibitors

Autor: Mamat, C., Pretze, M., Neuber, C., Mosch, B., Steinbach, J., Pietzsch, J.

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals 58(2015), S165
21st International Symposium on Radiopharmaceutical Sciences (ISRS), 26.-31.05.2015, Columbia/Missouri, USA

Objectives: The overexpression of various Eph receptors in tumors provokes the recent interest in highly affine inhibitors as attractive leads for the development of new targeted radioligands to image cancer [1]. Selective Ephtyrosine kinase inhibito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3cd27dda124f06e9b507f9a744d0e26d
https://www.hzdr.de/publications/Publ-22085-2

Charakterisierung der szintigraphischen Bildgebungseigenschaften von Pb-212 – Phantommessungen und erste klinische Aufnahmen

Autor: Kästner, D., Michler, E., Hartmann, H., Pretze, M., Freudenberg, R., Brogsitter, C., Schultz, M. K., Kotzerke, J.

Publikováno v: Nuklearmedizin. Nuclear medicine; March 2024, Vol. 63 Issue: 2